Regulation of Cell Proliferation and Differentiation by PPARβ/δ

por Müller, Rolf, Rieck, Markus, Müller-Brüsselbach, Sabine
Publicado 2008

A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis

por Müller, Rolf, Kömhoff, Martin, Peters, Jeffrey M., Müller-Brüsselbach, Sabine
Publicado 2008

Reverse crosstalk of TGFβ and PPARβ/δ signaling identified by transcriptional profiling

por Stockert, Josefine, Adhikary, Till, Kaddatz, Kerstin, Finkernagel, Florian, Meissner, Wolfgang, Müller-Brüsselbach, Sabine, Müller, Rolf
Publicado 2011

Regulation of TAK1/TAB1-Mediated IL-1β Signaling by Cytoplasmic PPARβ/δ

por Stockert, Josefine, Wolf, Alexander, Kaddatz, Kerstin, Schnitzer, Evelyn, Finkernagel, Florian, Meissner, Wolfgang, Müller-Brüsselbach, Sabine, Kracht, Michael, Müller, Rolf
Publicado 2013

A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory sec...

por Rohnalter, Verena, Roth, Katrin, Finkernagel, Florian, Adhikary, Till, Obert, Julia, Dorzweiler, Kristina, Bensberg, Maike, Müller-Brüsselbach, Sabine, Müller, Rolf
Publicado 2015

Genomewide Analyses Define Different Modes of Transcriptional Regulation by Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ)

por Adhikary, Till, Kaddatz, Kerstin, Finkernagel, Florian, Schönbauer, Anne, Meissner, Wolfgang, Scharfe, Maren, Jarek, Michael, Blöcker, Helmut, Müller-Brüsselbach, Sabine, Müller, Rolf
Publicado 2011

Interferon signaling in ascites-associated macrophages is linked to a favorable clinical outcome in a subgroup of ovarian carcinoma patients

por Adhikary, Till, Wortmann, Annika, Finkernagel, Florian, Lieber, Sonja, Nist, Andrea, Stiewe, Thorsten, Wagner, Uwe, Müller-Brüsselbach, Sabine, Reinartz, Silke, Müller, Rolf
Publicado 2017

Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse

por Reinartz, Silke, Schumann, Tim, Finkernagel, Florian, Wortmann, Annika, Jansen, Julia M, Meissner, Wolfgang, Krause, Michael, Schwörer, Anne-Marie, Wagner, Uwe, Müller-Brüsselbach, Sabine, Müller, Rolf
Publicado 2014

The multicellular signalling network of ovarian cancer metastases

por Sommerfeld, Leah, Finkernagel, Florian, Jansen, Julia M., Wagner, Uwe, Nist, Andrea, Stiewe, Thorsten, Müller‐Brüsselbach, Sabine, Sokol, Anna M., Graumann, Johannes, Reinartz, Silke, Müller, Rolf
Publicado 2021

The lysophosphatidic acid-regulated signal transduction network in ovarian cancer cells and its role in actomyosin dynamics, cell migration and entosis

por Ojasalu, Kaire, Lieber, Sonja, Sokol, Anna M., Nist, Andrea, Stiewe, Thorsten, Bullwinkel, Imke, Finkernagel, Florian, Reinartz, Silke, Müller-Brüsselbach, Sabine, Grosse, Robert, Graumann, Johannes, Müller, Rolf
Publicado 2023

Basal cell adhesion molecule promotes metastasis‐associated processes in ovarian cancer

por Sivakumar, Suresh, Lieber, Sonja, Librizzi, Damiano, Keber, Corinna, Sommerfeld, Leah, Finkernagel, Florian, Roth, Katrin, Reinartz, Silke, Bartsch, Jörg W., Graumann, Johannes, Müller‐Brüsselbach, Sabine, Müller, Rolf
Publicado 2023

Chromatin Binding of c-REL and p65 Is Not Limiting for Macrophage IL12B Transcription During Immediate Suppression by Ovarian Carcinoma Ascites

por Unger, Annika, Finkernagel, Florian, Hoffmann, Nathalie, Neuhaus, Felix, Joos, Barbara, Nist, Andrea, Stiewe, Thorsten, Visekruna, Alexander, Wagner, Uwe, Reinartz, Silke, Müller-Brüsselbach, Sabine, Müller, Rolf, Adhikary, Till
Publicado 2018

Prostacyclin Released by Cancer-Associated Fibroblasts Promotes Immunosuppressive and Pro-Metastatic Macrophage Polarization in the Ovarian Cancer Microenvironment

por Sommerfeld, Leah, Knuth, Isabel, Finkernagel, Florian, Pesek, Jelena, Nockher, Wolfgang A., Jansen, Julia M., Wagner, Uwe, Nist, Andrea, Stiewe, Thorsten, Müller-Brüsselbach, Sabine, Müller, Rolf, Reinartz, Silke
Publicado 2022

The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization

por Finkernagel, Florian, Reinartz, Silke, Lieber, Sonja, Adhikary, Till, Wortmann, Annika, Hoffmann, Nathalie, Bieringer, Tim, Nist, Andrea, Stiewe, Thorsten, Jansen, Julia M., Wagner, Uwe, Müller-Brüsselbach, Sabine, Müller, Rolf
Publicado 2016

A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome

por Reinartz, Silke, Finkernagel, Florian, Adhikary, Till, Rohnalter, Verena, Schumann, Tim, Schober, Yvonne, Nockher, W. Andreas, Nist, Andrea, Stiewe, Thorsten, Jansen, Julia M., Wagner, Uwe, Müller-Brüsselbach, Sabine, Müller, Rolf
Publicado 2016

The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state

por Adhikary, Till, Wortmann, Annika, Schumann, Tim, Finkernagel, Florian, Lieber, Sonja, Roth, Katrin, Toth, Philipp M., Diederich, Wibke E., Nist, Andrea, Stiewe, Thorsten, Kleinesudeik, Lara, Reinartz, Silke, Müller-Brüsselbach, Sabine, Müller, Rolf
Publicado 2015

Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures

por Hammoud, Mohamad K., Dietze, Raimund, Pesek, Jelena, Finkernagel, Florian, Unger, Annika, Bieringer, Tim, Nist, Andrea, Stiewe, Thorsten, Bhagwat, Aditya M., Nockher, Wolfgang Andreas, Reinartz, Silke, Müller‐Brüsselbach, Sabine, Graumann, Johannes, Müller, Rolf
Publicado 2022

Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion

por Adhikary, T, Brandt, D T, Kaddatz, K, Stockert, J, Naruhn, S, Meissner, W, Finkernagel, F, Obert, J, Lieber, S, Scharfe, M, Jarek, M, Toth, P M, Scheer, F, Diederich, W E, Reinartz, S, Grosse, R, Müller-Brüsselbach, S, Müller, R
Publicado 2013

Upregulation of mesothelial genes in ovarian carcinoma cells is associated with an unfavorable clinical outcome and the promotion of cancer cell adhesion

por Ojasalu, Kaire, Brehm, Corinna, Hartung, Kristin, Nischak, Maximilian, Finkernagel, Florian, Rexin, Peter, Nist, Andrea, Pavlakis, Evangelos, Stiewe, Thorsten, Jansen, Julia M., Wagner, Uwe, Gattenlöhner, Stefan, Bräuninger, Andreas, Müller‐Brüsselbach, Sabine, Reinartz, Silke, Müller, Rolf
Publicado 2020

Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment

por Schumann, Tim, Adhikary, Till, Wortmann, Annika, Finkernagel, Florian, Lieber, Sonja, Schnitzer, Evelyn, Legrand, Nathalie, Schober, Yvonne, Nockher, W. Andreas, Toth, Philipp M., Diederich, Wibke E., Nist, Andrea, Stiewe, Thorsten, Wagner, Uwe, Reinartz, Silke, Müller-Brüsselbach, Sabine, Müller, Rolf
Publicado 2015