Concomitant use of tamoxifen and endoxifen in postmenopausal early breast cancer: prediction of plasma levels by physiologically-based pharmacokinetic modeling

por Dickschen, Kristin, Eissing, Thomas, Mürdter, Thomas, Schwab, Matthias, Willmann, Stefan, Hempel, Georg
Publicado 2014

Physiologically Based Pharmacokinetic Modeling to Describe the CYP2D6 Activity Score-Dependent Metabolism of Paroxetine, Atomoxetine and Risperidone

por Rüdesheim, Simeon, Selzer, Dominik, Mürdter, Thomas, Igel, Svitlana, Kerb, Reinhold, Schwab, Matthias, Lehr, Thorsten
Publicado 2022

Diclofenac does not interact with codeine metabolism in vivo: A study in healthy volunteers

por Ammon, Susanne, Marx, Claudia, Behrens, Christoph, Hofmann, Ute, Mürdter, Thomas, Griese, Ernst-Ulrich, Mikus, Gerd
Publicado 2002

Protocol for establishing a coculture with fibroblasts and colorectal cancer organoids

por Wallisch, Svenja, Neef, Sylvia Karin, Denzinger, Lukas, Mönch, Dina, Koch, Jana, Marzi, Julia, Mürdter, Thomas, Janssen, Nicole
Publicado 2023

Raman Imaging and Fluorescence Lifetime Imaging Microscopy for Diagnosis of Cancer State and Metabolic Monitoring

por Becker, Lucas, Janssen, Nicole, Layland, Shannon L., Mürdter, Thomas E., Nies, Anne T., Schenke-Layland, Katja, Marzi, Julia
Publicado 2021

Dasatinib reverses Cancer-associated Fibroblasts (CAFs) from primary Lung Carcinomas to a Phenotype comparable to that of normal Fibroblasts

por Haubeiss, Silke, Schmid, Jens O, Mürdter, Thomas E, Sonnenberg, Maike, Friedel, Godehard, van der Kuip, Heiko, Aulitzky, Walter E
Publicado 2010

Monitoring the initial pulmonary absorption of two different beclomethasone dipropionate aerosols employing a human lung reperfusion model

por Freiwald, Matthias, Valotis, Anagnostis, Kirschbaum, Andreas, McClellan, Monika, Mürdter, Thomas, Fritz, Peter, Friedel, Godehard, Thomas, Michael, Högger, Petra
Publicado 2005

Pharmacologic Targeting of MMP2/9 Decreases Peritoneal Metastasis Formation of Colorectal Cancer in a Human Ex Vivo Peritoneum Culture Model

por Koch, Jana, Mönch, Dina, Maaß, Annika, Mangold, Alina, Gužvić, Miodrag, Mürdter, Thomas, Leibold, Tobias, Dahlke, Marc-H., Renner, Philipp
Publicado 2022

Intraperitoneal Chemotherapy of Peritoneal Carcinomatosis Using Pressurized Aerosol as an Alternative to Liquid Solution: First Evidence for Efficacy

por Solass, Wiebke, Kerb, Reinhold, Mürdter, Thomas, Giger-Pabst, Urs, Strumberg, Dirk, Tempfer, Clemens, Zieren, Jürgen, Schwab, Matthias, Reymond, Marc André
Publicado 2013

Clinical Trial: CYP2D6 Related Dose Escalation of Tamoxifen in Breast Cancer Patients With Iranian Ethnic Background Resulted in Increased Concentrations of Tamoxifen and Its Metab...

por Khalaj, Zahra, Baratieh, Zohreh, Nikpour, Parvaneh, Schwab, Matthias, Schaeffeler, Elke, Mokarian, Fariborz, Khanahmad, Hossein, Salehi, Rasoul, Mürdter, Thomas E., Salehi, Mansoor
Publicado 2019

Highly variable response to cytotoxic chemotherapy in carcinoma-associated fibroblasts (CAFs) from lung and breast

por Sonnenberg, Maike, van der Kuip, Heiko, Haubeiß, Silke, Fritz, Peter, Schroth, Werner, Friedel, Godehard, Simon, Wolfgang, Mürdter, Thomas E, Aulitzky, Walter E
Publicado 2008

The formation of estrogen-like tamoxifen metabolites and their influence on enzyme activity and gene expression of ADME genes

por Johänning, Janina, Kröner, Patrick, Thomas, Maria, Zanger, Ulrich M., Nörenberg, Astrid, Eichelbaum, Michel, Schwab, Matthias, Brauch, Hiltrud, Schroth, Werner, Mürdter, Thomas E.
Publicado 2017

Metabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS

por Neef, Sylvia K., Janssen, Nicole, Winter, Stefan, Wallisch, Svenja K., Hofmann, Ute, Dahlke, Marc H., Schwab, Matthias, Mürdter, Thomas E., Haag, Mathias
Publicado 2020

Short term culture of breast cancer tissues to study the activity of the anticancer drug taxol in an intact tumor environment

por van der Kuip, Heiko, Mürdter, Thomas E, Sonnenberg, Maike, McClellan, Monika, Gutzeit, Susanne, Gerteis, Andreas, Simon, Wolfgang, Fritz, Peter, Aulitzky, Walter E
Publicado 2006

Simulation-Based Assessment of the Impact of Non-Adherence on Endoxifen Target Attainment in Different Tamoxifen Dosing Strategies

por Mueller-Schoell, Anna, Klopp-Schulze, Lena, Michelet, Robin, van Dyk, Madelé, Mürdter, Thomas E., Schwab, Matthias, Joerger, Markus, Huisinga, Wilhelm, Mikus, Gerd, Kloft, Charlotte
Publicado 2021

Computational Treatment Simulations to Assess the Need for Personalized Tamoxifen Dosing in Breast Cancer Patients of Different Biogeographical Groups

por Mueller-Schoell, Anna, Michelet, Robin, Klopp-Schulze, Lena, van Dyk, Madelé, Mürdter, Thomas E., Schwab, Matthias, Joerger, Markus, Huisinga, Wilhelm, Mikus, Gerd, Kloft, Charlotte
Publicado 2021

Prediction of Drug–Drug–Gene Interaction Scenarios of (E)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic Modeling

por Kovar, Christina, Kovar, Lukas, Rüdesheim, Simeon, Selzer, Dominik, Ganchev, Boian, Kröner, Patrick, Igel, Svitlana, Kerb, Reinhold, Schaeffeler, Elke, Mürdter, Thomas E., Schwab, Matthias, Lehr, Thorsten
Publicado 2022

A human ex vivo coculture model to investigate peritoneal metastasis and innovative treatment options

por Mönch, Dina, Koch, Jana, Maaß, Annika, Janssen, Nicole, Mürdter, Thomas, Renner, Philipp, Fallier-Becker, Petra, Solaß, Wiebke, Schwab, Matthias, Dahlke, Marc-H., Schlitt, Hans J., Leibold, Tobias
Publicado 2021

Improved Prediction of Endoxifen Metabolism by CYP2D6 Genotype in Breast Cancer Patients Treated with Tamoxifen

por Schroth, Werner, Winter, Stefan, Mürdter, Thomas, Schaeffeler, Elke, Eccles, Diana, Eccles, Bryony, Chowbay, Balram, Khor, Chiea C., Tfayli, Arafat, Zgheib, Nathalie K., Eichelbaum, Michel, Schwab, Matthias, Brauch, Hiltrud
Publicado 2017

Oncogenic Ras triggers hyperproliferation and impairs polarized colonic morphogenesis by autocrine ErbB3 signaling

por Möller, Yvonne, Morkel, Markus, Schmid, Jens, Beyes, Sven, Hendrick, Janina, Strotbek, Michaela, Riemer, Pamela, Schmid, Simone, Schmitt, Lisa C., Kontermann, Roland, Mürdter, Thomas, Schwab, Matthias, Sers, Christine, Olayioye, Monilola A.
Publicado 2016