The role of LIN28B in tumor progression and metastasis in solid tumor entities

por GEWALT, TABEA, NOH, KA-WON, MEDER, LYDIA
Publicado 2023

SQSTM1/p62 promotes miR-198 loading into extracellular vesicles and its autophagy-related secretion

por Yu, Xiaojie, Eischeid-Scholz, Hannah, Meder, Lydia, Kondylis, Vangelis, Büttner, Reinhard, Odenthal, Margarete
Publicado 2022

EGFR Inhibition Strongly Modulates the Tumour Immune Microenvironment in EGFR-Driven Non-Small-Cell Lung Cancer

por Selenz, Carolin, Compes, Anik, Nill, Marieke, Borchmann, Sven, Odenthal, Margarete, Florin, Alexandra, Brägelmann, Johannes, Büttner, Reinhard, Meder, Lydia, Ullrich, Roland T.
Publicado 2022

Trophoblast Cell Surface Antigen 2 (TROP2) as a Predictive Bio-Marker for the Therapeutic Efficacy of Sacituzumab Govitecan in Adenocarcinoma of the Esophagus

por Hoppe, Sascha, Meder, Lydia, Gebauer, Florian, Ullrich, Roland T., Zander, Thomas, Hillmer, Axel M., Buettner, Reinhard, Plum, Patrick, Puppe, Julian, Malter, Wolfram, Quaas, Alexander
Publicado 2022

Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo

por Mittenbühler, Melanie J., Saedler, Katarzyna, Nolte, Hendrik, Kern, Lara, Zhou, Jun, Qian, Shu-Bing, Meder, Lydia, Ullrich, Roland T., Brüning, Jens C., Wunderlich, F. Thomas
Publicado 2020

Loss of the Keratin Cytoskeleton Is Not Sufficient to Induce Epithelial Mesenchymal Transition in a Novel KRAS Driven Sporadic Lung Cancer Mouse Model

por König, Katharina, Meder, Lydia, Kröger, Cornelia, Diehl, Linda, Florin, Alexandra, Rommerscheidt-Fuss, Ursula, Kahl, Philip, Wardelmann, Eva, Magin, Thomas M., Buettner, Reinhard, Heukamp, Lukas C.
Publicado 2013

Notch1 Deficiency Induces Tumor Cell Accumulation Inside the Bronchiolar Lumen and Increases TAZ Expression in an Autochthonous Kras (LSL-G12V) Driven Lung Cancer Mouse Model

por Meder, Lydia, Florin, Alexandra, Ozretić, Luka, Nill, Marieke, Koker, Mirjam, Meemboor, Sonja, Radtke, Freddy, Diehl, Linda, Ullrich, Roland T., Odenthal, Margarete, Büttner, Reinhard, Heukamp, Lukas C.
Publicado 2021

Preclinical studies reveal that LSD1 inhibition results in tumor growth arrest in lung adenocarcinoma independently of driver mutations

por Macheleidt, Iris F., Dalvi, Priya S., Lim, So‐Young, Meemboor, Sonja, Meder, Lydia, Käsgen, Olivia, Müller, Marion, Kleemann, Karolin, Wang, Lingyu, Nürnberg, Peter, Rüsseler, Vanessa, Schäfer, Stephan C., Mahabir, Esther, Büttner, Reinhard, Odenthal, Margarete
Publicado 2018

Pericentromeric Satellite III transcripts induce etoposide resistance

por Kanne, Julian, Hussong, Michelle, Isensee, Jörg, Muñoz-López, Álvaro, Wolffgramm, Jan, Heß, Felix, Grimm, Christina, Bessonov, Sergey, Meder, Lydia, Wang, Jie, Reinhardt, H. Christian, Odenthal, Margarete, Hucho, Tim, Büttner, Reinhard, Summerer, Daniel, Schweiger, Michal R.
Publicado 2021

NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas

por Meder, Lydia, König, Katharina, Ozretić, Luka, Schultheis, Anne M., Ueckeroth, Frank, Ade, Carsten P., Albus, Kerstin, Boehm, Diana, Rommerscheidt‐Fuss, Ursula, Florin, Alexandra, Buhl, Theresa, Hartmann, Wolfgang, Wolf, Jürgen, Merkelbach‐Bruse, Sabine, Eilers, Martin, Perner, Sven, Heukamp, Lukas C., Buettner, Reinhard
Publicado 2015

Tripartite antigen-agnostic combination immunotherapy cures established poorly immunogenic tumors

por Borchmann, Sven, Selenz, Carolin, Lohmann, Mia, Ludwig, Hanna, Gassa, Asmae, Brägelmann, Johannes, Lohneis, Philipp, Meder, Lydia, Mattlener, Julia, Breid, Sara, Nill, Marieke, Fassunke, Jana, Wisdom, Amy J., Compes, Anik, Gathof, Birgit, Alakus, Hakan, Kirsch, David, Hekmat, Khosro, Büttner, Reinhard, Reinhardt, H. Christian, Hallek, Michael, Ullrich, Roland T.
Publicado 2022

Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer

por Malchers, Florian, Nogova, Lucia, van Attekum, Martijn H.A., Maas, Lukas, Brägelmann, Johannes, Bartenhagen, Christoph, Girard, Luc, Bosco, Graziella, Dahmen, Ilona, Michels, Sebastian, Weeden, Clare E., Scheel, Andreas H., Meder, Lydia, Golfmann, Kristina, Schuldt, Philipp, Siemanowski, Janna, Rehker, Jan, Merkelbach-Bruse, Sabine, Menon, Roopika, Gautschi, Oliver, Heuckmann, Johannes M., Brambilla, Elisabeth, Asselin-Labat, Marie-Liesse, Persigehl, Thorsten, Minna, John D., Walczak, Henning, Ullrich, Roland T., Fischer, Matthias, Reinhardt, Hans Christian, Wolf, Jürgen, Büttner, Reinhard, Peifer, Martin, George, Julie, Thomas, Roman K.
Publicado 2023

MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I

por Brägelmann, Johannes, Lorenz, Carina, Borchmann, Sven, Nishii, Kazuya, Wegner, Julia, Meder, Lydia, Ostendorp, Jenny, Ast, David F., Heimsoeth, Alena, Nakasuka, Takamasa, Hirabae, Atsuko, Okawa, Sachi, Dammert, Marcel A., Plenker, Dennis, Klein, Sebastian, Lohneis, Philipp, Gu, Jianing, Godfrey, Laura K., Forster, Jan, Trajkovic-Arsic, Marija, Zillinger, Thomas, Haarmann, Mareike, Quaas, Alexander, Lennartz, Stefanie, Schmiel, Marcel, D’Rozario, Joshua, Thomas, Emily S., Li, Henry, Schmitt, Clemens A., George, Julie, Thomas, Roman K., von Karstedt, Silvia, Hartmann, Gunther, Büttner, Reinhard, Ullrich, Roland T., Siveke, Jens T., Ohashi, Kadoaki, Schlee, Martin, Sos, Martin L.
Publicado 2021