A novel telomerase substrate precursor rapidly induces telomere dysfunction in telomerase positive cancer cells but not telomerase silent normal cells

por Mender, Ilgen, Gryaznov, Sergei, Shay, Jerry W.
Publicado 2015

Imetelstat (a telomerase antagonist) exerts off-target effects on the cytoskeleton

por MENDER, ILGEN, SENTURK, SERIF, OZGUNES, NURIMAN, AKCALI, K. CAN, KLETSAS, DIMITRIS, GRYAZNOV, SERGEI, CAN, ALP, SHAY, JERRY W., DIKMEN, Z. GUNNUR
Publicado 2013

A method for measuring the distribution of the shortest telomeres in cells and tissues

por Lai, Tsung-Po, Zhang, Ning, Noh, Jungsik, Mender, Ilgen, Tedone, Enzo, Huang, Ejun, Wright, Woodring E., Danuser, Gaudenz, Shay, Jerry W.
Publicado 2017

Regulation of the Human Telomerase Gene TERT by Telomere Position Effect—Over Long Distances (TPE-OLD): Implications for Aging and Cancer

por Kim, Wanil, Ludlow, Andrew T., Min, Jaewon, Robin, Jerome D., Stadler, Guido, Mender, Ilgen, Lai, Tsung-Po, Zhang, Ning, Wright, Woodring E., Shay, Jerry W.
Publicado 2016

Exploiting TERT dependency as a therapeutic strategy for NRAS-mutant melanoma

por Reyes-Uribe, Patricia, Adrianzen-Ruesta, Maria Paz, Deng, Zhong, Echevarria-Vargas, Ileabett, Mender, Ilgen, Saheb, Steven, Liu, Qin, Altieri, Dario C., Murphy, Maureen E., Shay, Jerry W., Lieberman, Paul M., Villanueva, Jessie
Publicado 2018

NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer

por Ludlow, Andrew T., Wong, Mandy Sze, Robin, Jerome D., Batten, Kimberly, Yuan, Laura, Lai, Tsung-Po, Dahlson, Nicole, Zhang, Lu, Mender, Ilgen, Tedone, Enzo, Sayed, Mohammed E., Wright, Woodring E., Shay, Jerry W.
Publicado 2018

Activating an Adaptive Immune Response with a Telomerase-Mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma

por Mender, Ilgen, Siteni, Silvia, Barron, Summer, Flusche, Ann Marie, Kubota, Naoto, Yu, Chunhua, Cornelius, Crystal, Tedone, Enzo, Maziveyi, Mazvita, Grichuk, Anthony, Venkateswaran, Niranjan, Conacci-Sorrell, Maralice, Hoshida, Yujin, Kang, Rui, Tang, Daolin, Gryaznov, Sergei, Shay, Jerry W.
Publicado 2023

Telomerase-Mediated Strategy for Overcoming Non–Small Cell Lung Cancer Targeted Therapy and Chemotherapy Resistance

por Mender, Ilgen, LaRanger, Ryan, Luitel, Krishna, Peyton, Michael, Girard, Luc, Lai, Tsung-Po, Batten, Kimberly, Cornelius, Crystal, Dalvi, Maithili P., Ramirez, Michael, Du, Wenting, Wu, Lani F., Altschuler, Steven J., Brekken, Rolf, Martinez, Elisabeth D., Minna, John D., Wright, Woodring E., Shay, Jerry W.
Publicado 2018