Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis

por MINA, JOHN G. M., DENNY, P. W.
Publicado 2018

Assessment of Toxoplasma gondii lytic cycle and the impact of a gene deletion using 3D label-free optical diffraction holotomography

por Koutsogiannis, Zisis, Mina, John G. M., Suman, Rakesh, Denny, Paul William
Publicado 2023

ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain

por Cabukusta, Birol, Kol, Matthijs, Kneller, Laura, Hilderink, Angelika, Bickert, Andreas, Mina, John G. M., Korneev, Sergei, Holthuis, Joost C. M.
Publicado 2017

Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania

por Trinconi, Cristiana T., Miguel, Danilo C., Silber, Ariel M., Brown, Christopher, Mina, John G.M., Denny, Paul W., Heise, Norton, Uliana, Silvia R.B.
Publicado 2018

Illuminating Host-Parasite Interaction at the Cellular and Subcellular Levels with Infrared Microspectroscopy

por Elsheikha, Hany M., Al-Sandaqchi, Alaa T., Harun, Mohammad S. R., Winterton, Francesca, Altharawi, Ali, Elsaied, Nashwa A., Stevenson, Carl W., MacNaughtan, William, Mina, John G. M., Denny, Paul W., Cinque, Gianfelice, Chan, Ka Lung Andrew
Publicado 2022

Ceramides bind VDAC2 to trigger mitochondrial apoptosis

por Dadsena, Shashank, Bockelmann, Svenja, Mina, John G. M., Hassan, Dina G., Korneev, Sergei, Razzera, Guilherme, Jahn, Helene, Niekamp, Patrick, Müller, Dagmar, Schneider, Markus, Tafesse, Fikadu G., Marrink, Siewert J., Melo, Manuel N., Holthuis, Joost C. M.
Publicado 2019

Antileishmanial Chemotherapy through Clemastine Fumarate Mediated Inhibition of the Leishmania Inositol Phosphorylceramide Synthase

por Mina, John G. M., Charlton, Rebecca L., Alpizar-Sosa, Edubiel, Escrivani, Douglas O., Brown, Christopher, Alqaisi, Amjed, Borsodi, Maria Paula G., Figueiredo, Claudia P., de Lima, Emanuelle V., Dickie, Emily A., Wei, Wenbin, Coutinho-Silva, Robson, Merritt, Andy, Smith, Terry K., Barrett, Michael P., Rossi-Bergmann, Bartira, Denny, Paul W., Steel, Patrick G.
Publicado 2020