Searching for stem cells in the adult pancreas: A futile effort?

por Minami, Kohtaro
Publicado 2013

GATA transcription factors: New key regulators in pancreas organogenesis

por Minami, Kohtaro
Publicado 2013

Current status of regeneration of pancreatic β‐cells

por Minami, Kohtaro, Seino, Susumu
Publicado 2013

Pancreatic β-cell signaling: toward better understanding of diabetes and its treatment

por SEINO, Susumu, SHIBASAKI, Tadao, MINAMI, Kohtaro
Publicado 2010

Tracing phenotypic reversibility of pancreatic β‐cells in vitro

por Minami, Kohtaro, Miyawaki, Kazumasa, Hara, Manami, Yamada, Shuichi, Seino, Susumu
Publicado 2010

Liraglutide Improves Pancreatic Beta Cell Mass and Function in Alloxan-Induced Diabetic Mice

por Tamura, Kanako, Minami, Kohtaro, Kudo, Maya, Iemoto, Keisuke, Takahashi, Harumi, Seino, Susumu
Publicado 2015

Drug delivery for neuronopathic lysosomal storage diseases: evolving roles of the blood brain barrier and cerebrospinal fluid

por Sato, Yuji, Minami, Kohtaro, Hirato, Toru, Tanizawa, Kazunori, Sonoda, Hiroyuki, Schmidt, Mathias
Publicado 2022

Establishment of new clonal pancreatic β‐cell lines (MIN6‐K) useful for study of incretin/cyclic adenosine monophosphate signaling

por Iwasaki, Masahiro, Minami, Kohtaro, Shibasaki, Tadao, Miki, Takashi, Miyazaki, Jun‐ichi, Seino, Susumu
Publicado 2010

Nonclinical safety evaluation of pabinafusp alfa, an anti-human transferrin receptor antibody and iduronate-2-sulfatase fusion protein, for the treatment of neuronopathic mucopolys...

por Yamamoto, Ryuji, Yoden, Eiji, Tanaka, Noboru, Kinoshita, Masafumi, Imakiire, Atsushi, Hirato, Tohru, Minami, Kohtaro
Publicado 2021

Dose-dependent effects of a brain-penetrating iduronate-2-sulfatase on neurobehavioral impairments in mucopolysaccharidosis II mice

por Morimoto, Hideto, Morioka, Hiroki, Imakiire, Atsushi, Yamamoto, Ryuji, Hirato, Tohru, Sonoda, Hiroyuki, Minami, Kohtaro
Publicado 2022

In vitro generation of insulin‐secreting cells from human pancreatic exocrine cells

por Minami, Kohtaro, Doi, Ryuichiro, Kawaguchi, Yoshiya, Nukaya, Daiki, Hagiwara, Yoshiaki, Noguchi, Hirofumi, Matsumoto, Shinichi, Seino, Susumu
Publicado 2011

Pathogenic Roles of Heparan Sulfate and Its Use as a Biomarker in Mucopolysaccharidoses

por Minami, Kohtaro, Morimoto, Hideto, Morioka, Hiroki, Imakiire, Atsushi, Kinoshita, Masafumi, Yamamoto, Ryuji, Hirato, Tohru, Sonoda, Hiroyuki
Publicado 2022

Essential roles of aspartate aminotransferase 1 and vesicular glutamate transporters in β-cell glutamate signaling for incretin-induced insulin secretion

por Murao, Naoya, Yokoi, Norihide, Honda, Kohei, Han, Guirong, Hayami, Tomohide, Gheni, Ghupurjan, Takahashi, Harumi, Minami, Kohtaro, Seino, Susumu
Publicado 2017

Treatment of Neuronopathic Mucopolysaccharidoses with Blood–Brain Barrier-Crossing Enzymes: Clinical Application of Receptor-Mediated Transcytosis

por Sonoda, Hiroyuki, Takahashi, Kenichi, Minami, Kohtaro, Hirato, Toru, Yamamoto, Tatsuyoshi, So, Sairei, Tanizawa, Kazunori, Schmidt, Mathias, Sato, Yuji
Publicado 2022

Iduronate-2-Sulfatase with Anti-human Transferrin Receptor Antibody for Neuropathic Mucopolysaccharidosis II: A Phase 1/2 Trial

por Okuyama, Torayuki, Eto, Yoshikatsu, Sakai, Norio, Minami, Kohtaro, Yamamoto, Tatsuyoshi, Sonoda, Hiroyuki, Yamaoka, Mariko, Tachibana, Katsuhiko, Hirato, Tohru, Sato, Yuji
Publicado 2019

A Novel Diphenylthiosemicarbazide Is a Potential Insulin Secretagogue for Anti-Diabetic Agent

por Sugawara, Kenji, Honda, Kohei, Reien, Yoshie, Yokoi, Norihide, Seki, Chihiro, Takahashi, Harumi, Minami, Kohtaro, Mori, Ichiro, Matsumoto, Akio, Nakaya, Haruaki, Seino, Susumu
Publicado 2016

Meal sequence and glucose excursion, gastric emptying and incretin secretion in type 2 diabetes: a randomised, controlled crossover, exploratory trial

por Kuwata, Hitoshi, Iwasaki, Masahiro, Shimizu, Shinobu, Minami, Kohtaro, Maeda, Haruyo, Seino, Susumu, Nakada, Koji, Nosaka, Chihiro, Murotani, Kenta, Kurose, Takeshi, Seino, Yutaka, Yabe, Daisuke
Publicado 2015

Clearance of heparan sulfate in the brain prevents neurodegeneration and neurocognitive impairment in MPS II mice

por Morimoto, Hideto, Kida, Sachiho, Yoden, Eiji, Kinoshita, Masafumi, Tanaka, Noboru, Yamamoto, Ryuji, Koshimura, Yuri, Takagi, Haruna, Takahashi, Kenichi, Hirato, Tohru, Minami, Kohtaro, Sonoda, Hiroyuki
Publicado 2021

A Blood-Brain-Barrier-Penetrating Anti-human Transferrin Receptor Antibody Fusion Protein for Neuronopathic Mucopolysaccharidosis II

por Sonoda, Hiroyuki, Morimoto, Hideto, Yoden, Eiji, Koshimura, Yuri, Kinoshita, Masafumi, Golovina, Galina, Takagi, Haruna, Yamamoto, Ryuji, Minami, Kohtaro, Mizoguchi, Akira, Tachibana, Katsuhiko, Hirato, Tohru, Takahashi, Kenichi
Publicado 2018

Transferrin Receptor-Targeted Iduronate-2-sulfatase Penetrates the Blood-Retinal Barrier and Improves Retinopathy in Mucopolysaccharidosis II Mice

por Imakiire, Atsushi, Morimoto, Hideto, Suzuki, Hidehiko, Masuda, Tomomi, Yoden, Eiji, Inoue, Asuka, Morioka, Hiroki, Konaka, Takashi, Mori, Ayaka, Shirasaka, Ryoji, Kato, Ryo, Hirato, Tohru, Sonoda, Hiroyuki, Minami, Kohtaro
Publicado 2023