Revolutionizing male fertility factor research in mice by using the genome editing tool CRISPR/Cas9

por Abbasi, Ferheen, Miyata, Haruhiko, Ikawa, Masahito
Publicado 2017

Factors controlling sperm migration through the oviduct revealed by gene-modified mouse models

por Fujihara, Yoshitaka, Miyata, Haruhiko, Ikawa, Masahito
Publicado 2018

Analysis of the sperm flagellar axoneme using gene-modified mice

por Miyata, Haruhiko, Morohoshi, Akane, Ikawa, Masahito
Publicado 2020

Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis

por SHIMADA, Keisuke, KATO, Hirotaka, MIYATA, Haruhiko, IKAWA, Masahito
Publicado 2019

The motor domain of testis-enriched kinesin KIF9 is essential for its localization in the mouse flagellum

por Miyata, Haruhiko, Oyama, Yuki, Kaneda, Yuki, Ikawa, Masahito
Publicado 2021

CRISPR/CAS9-mediated amino acid substitution reveals phosphorylation residues of RSPH6A are not essential for male fertility in mice

por Miyata, Haruhiko, Abbasi, Ferheen, Visconti, Pablo E, Ikawa, Masahito
Publicado 2020

Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA

por Mashiko, Daisuke, Fujihara, Yoshitaka, Satouh, Yuhkoh, Miyata, Haruhiko, Isotani, Ayako, Ikawa, Masahito
Publicado 2013

FAM71F1 binds to RAB2A and RAB2B and is essential for acrosome formation and male fertility in mice

por Morohoshi, Akane, Miyata, Haruhiko, Oyama, Yuki, Oura, Seiya, Noda, Taichi, Ikawa, Masahito
Publicado 2021

TULP2 deletion mice exhibit abnormal outer dense fiber structure and male infertility

por Oyama, Yuki, Miyata, Haruhiko, Shimada, Keisuke, Larasati, Tamara, Fujihara, Yoshitaka, Ikawa, Masahito
Publicado 2022

The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution

por Sobajima, Tomoaki, Yoshimura, Shin-ichiro, Maeda, Tomomi, Miyata, Haruhiko, Miyoshi, Eiji, Harada, Akihiro
Publicado 2018

IRGC1, a testis-enriched immunity related GTPase, is important for fibrous sheath integrity and sperm motility in mice

por Kaneda, Yuki, Miyata, Haruhiko, Shimada, Keisuke, Oyama, Yuki, Iida-Norita, Rie, Ikawa, Masahito
Publicado 2022

Testis-enriched ferlin, FER1L5, is required for Ca(2+)-activated acrosome reaction and male fertility

por Morohoshi, Akane, Miyata, Haruhiko, Tokuhiro, Keizo, Iida-Norita, Rie, Noda, Taichi, Fujihara, Yoshitaka, Ikawa, Masahito
Publicado 2023

FBXO24 ensures male fertility by preventing abnormal accumulation of membraneless granules in sperm flagella

por Kaneda, Yuki, Miyata, Haruhiko, Xu, Zoulan, Shimada, Keisuke, Kamoshita, Maki, Nakagawa, Tatsuya, Emori, Chihiro, Ikawa, Masahito
Publicado 2023

Chimeric analysis with newly established EGFP/DsRed2-tagged ES cells identify HYDIN as essential for spermiogenesis in mice

por Oura, Seiya, Miyata, Haruhiko, Noda, Taichi, Shimada, Keisuke, Matsumura, Takafumi, Morohoshi, Akane, Isotani, Ayako, Ikawa, Masahito
Publicado 2018

Testis‐enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa

por Miyata, Haruhiko, Shimada, Keisuke, Morohoshi, Akane, Oura, Seiya, Matsumura, Takafumi, Xu, Zoulan, Oyama, Yuki, Ikawa, Masahito
Publicado 2020

Mouse t-complex protein 11 is important for progressive motility in sperm

por Castaneda, Julio M, Miyata, Haruhiko, Archambeault, Denise R, Satouh, Yuhkoh, Yu, Zhifeng, Ikawa, Masahito, Matzuk, Martin M
Publicado 2020

ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility

por Shimada, Keisuke, Park, Soojin, Miyata, Haruhiko, Yu, Zhifeng, Morohoshi, Akane, Oura, Seiya, Matzuk, Martin M., Ikawa, Masahito
Publicado 2021

A CUG-initiated CATSPERθ functions in the CatSper channel assembly and serves as a checkpoint for flagellar trafficking

por Huang, Xiaofang, Miyata, Haruhiko, Wang, Huafeng, Mori, Giulia, Iida-Norita, Rie, Ikawa, Masahito, Percudani, Riccardo, Chung, Jean-Ju
Publicado 2023

The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors

por Nakai, Akiko, Fujimoto, Jun, Miyata, Haruhiko, Stumm, Ralf, Narazaki, Masashi, Schulz, Stefan, Baba, Yoshihiro, Kumanogoh, Atsushi, Suzuki, Kazuhiro
Publicado 2019

Nexin-Dynein regulatory complex component DRC7 but not FBXL13 is required for sperm flagellum formation and male fertility in mice

por Morohoshi, Akane, Miyata, Haruhiko, Shimada, Keisuke, Nozawa, Kaori, Matsumura, Takafumi, Yanase, Ryuji, Shiba, Kogiku, Inaba, Kazuo, Ikawa, Masahito
Publicado 2020