Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis

por Hou, Jue, Ju, Jie, Zhang, Zili, Zhao, Cong, Li, Zhanhui, Zheng, Jiyue, Sheng, Tian, Zhang, Hongjian, Hu, Linkun, Yu, Xiaoliang, Zhang, Wei, Li, Yangxin, Wu, Meng, Ma, Haikuo, Zhang, Xiaohu, He, Sudan
Publicado 2019

Discovery of a Potent RIPK3 Inhibitor for the Amelioration of Necroptosis-Associated Inflammatory Injury

por Xia, Kaijiang, Zhu, Fang, Yang, Chengkui, Wu, Shuwei, Lin, Yu, Ma, Haikuo, Yu, Xiaoliang, Zhao, Cong, Ji, Yuting, Ge, Wenxiang, Wang, Jingrui, Du, Yayun, Zhang, Wei, Yang, Tao, Zhang, Xiaohu, He, Sudan
Publicado 2020

A novel RIPK1 inhibitor reduces GVHD in mice via a nonimmunosuppressive mechanism that restores intestinal homeostasis

por Yu, Xiaoliang, Ma, Haikuo, Li, Bohan, Ji, Yuting, Du, Yayun, Liu, Siying, Li, Zhanhui, Hao, Yongjin, Tian, Sheng, Zhao, Cong, Du, Qian, Jin, Zhongqin, Zhu, Xueming, Tian, Yuanyuan, Chen, Xin, Sun, Xue, Yang, Chengkui, Zhu, Fang, Ju, Jie, Zheng, Yunjing, Zhang, Wei, Wang, Jingrui, Yang, Tao, Wang, Xinhui, Li, Jingjing, Xu, Xiangping, Du, Shujing, Lu, Haohao, Ma, Feng, Zhang, Haibing, Zhang, Yi, Zhang, Xiaohu, Hu, Shaoyan, He, Sudan
Publicado 2023