Gene expression signatures of human cell and tissue longevity

por Seim, Inge, Ma, Siming, Gladyshev, Vadim N
Publicado 2016

Study on the Relationship between Unexplained Recurrent Abortion and HLA-DQ Gene Polymorphism

por Tang, Jie, Zhu, Jichao, Shu, Longwen, Huang, Xiaohong, Ma, Siming
Publicado 2022

Defining molecular basis for longevity traits in natural yeast isolates

por Kaya, Alaattin, Ma, Siming, Wasko, Brian, Lee, Mitchell, Kaeberlein, Matt, Gladyshev, Vadim N
Publicado 2015

Cooperative DNA binding mediated by KicGAS/ORF52 oligomerization allows inhibition of DNA-induced phase separation and activation of cGAS

por Bhowmik, Debipreeta, Du, Mingjian, Tian, Yuan, Ma, Siming, Wu, Jianjun, Chen, Zhijian, Yin, Qian, Zhu, Fanxiu
Publicado 2021

Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation

por Avanesov, Andrei S, Ma, Siming, Pierce, Kerry A, Yim, Sun Hee, Lee, Byung Cheon, Clish, Clary B, Gladyshev, Vadim N
Publicado 2014

Molecular Footprints of Aquatic Adaptation Including Bone Mass Changes in Cetaceans

por Zhou, Xuming, Sun, Di, Guang, Xuanmin, Ma, Siming, Fang, Xiaodong, Mariotti, Marco, Nielsen, Rasmus, Gladyshev, Vadim N, Yang, Guang
Publicado 2018

Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity

por Ma, Siming, Avanesov, Andrei S., Porter, Emily, Lee, Byung Cheon, Mariotti, Marco, Zemskaya, Nadezhda, Guigo, Roderic, Moskalev, Alexey A., Gladyshev, Vadim N.
Publicado 2018

Molecular signatures of aneuploidy-driven adaptive evolution

por Kaya, Alaattin, Mariotti, Marco, Tyshkovskiy, Alexander, Zhou, Xuming, Hulke, Michelle L., Ma, Siming, Gerashchenko, Maxim V., Koren, Amnon, Gladyshev, Vadim N.
Publicado 2020

Genetic perturbation of mitochondrial function reveals functional role for specific mitonuclear genes, metabolites, and pathways that regulate lifespan

por Phua, Cheryl Zi Jin, Zhao, Xiaqing, Turcios-Hernandez, Lesly, McKernan, Morrigan, Abyadeh, Morteza, Ma, Siming, Promislow, Daniel, Kaeberlein, Matt, Kaya, Alaattin
Publicado 2023

The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal

por Seim, Inge, Ma, Siming, Zhou, Xuming, Gerashchenko, Maxim V., Lee, Sang-Goo, Suydam, Robert, George, John C., Bickham, John W., Gladyshev, Vadim N.
Publicado 2014

Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino acid status

por Lee, Byung Cheon, Kaya, Alaattin, Ma, Siming, Kim, Gwansu, Gerashchenko, Maxim V., Yim, Sun Hee, Hu, Zhen, Harshman, Lawrence G., Gladyshev, Vadim N.
Publicado 2014

Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity

por Ma, Siming, Upneja, Akhil, Galecki, Andrzej, Tsai, Yi-Miau, Burant, Charles F, Raskind, Sasha, Zhang, Quanwei, Zhang, Zhengdong D, Seluanov, Andrei, Gorbunova, Vera, Clish, Clary B, Miller, Richard A, Gladyshev, Vadim N
Publicado 2016

Single-cell analysis reveals clonally expanded tumor-associated CD57(+) CD8 T cells are enriched in the periphery of patients with metastatic urothelial cancer responding to PD-L1...

por Fehlings, Michael, Kim, Leesun, Guan, Xiangnan, Yuen, Kobe, Tafazzol, Alireza, Sanjabi, Shomyseh, Zill, Oliver A, Rishipathak, Deepali, Wallace, Andrew, Nardin, Alessandra, Ma, Siming, Milojkovic, Ana, Newell, Evan W, Mariathasan, Sanjeev, Yadav, Mahesh
Publicado 2022

Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast

por Kaya, Alaattin, Phua, Cheryl Zi Jin, Lee, Mitchell, Wang, Lu, Tyshkovskiy, Alexander, Ma, Siming, Barre, Benjamin, Liu, Weiqiang, Harrison, Benjamin R, Zhao, Xiaqing, Zhou, Xuming, Wasko, Brian M, Bammler, Theo K, Promislow, Daniel EL, Kaeberlein, Matt, Gladyshev, Vadim N
Publicado 2021

A chromosome‐level genome of Antechinus flavipes provides a reference for an Australian marsupial genus with male death after mating

por Tian, Ran, Han, Kai, Geng, Yuepan, Yang, Chen, Shi, Chengcheng, Thomas, Patrick B., Pearce, Coral, Moffatt, Kate, Ma, Siming, Xu, Shixia, Yang, Guang, Zhou, Xuming, Gladyshev, Vadim N., Liu, Xin, Fisher, Diana O., Chopin, Lisa K., Leiner, Natália O., Baker, Andrew M., Fan, Guangyi, Seim, Inge
Publicado 2021

Genome analysis reveals insights into physiology and longevity of the Brandt’s bat Myotis brandtii

por Seim, Inge, Fang, Xiaodong, Xiong, Zhiqiang, Lobanov, Alexey V., Huang, Zhiyong, Ma, Siming, Feng, Yue, Turanov, Anton A., Zhu, Yabing, Lenz, Tobias L., Gerashchenko, Maxim V., Fan, Dingding, Hee Yim, Sun, Yao, Xiaoming, Jordan, Daniel, Xiong, Yingqi, Ma, Yong, Lyapunov, Andrey N., Chen, Guanxing, Kulakova, Oksana I., Sun, Yudong, Lee, Sang-Goo, Bronson, Roderick T., Moskalev, Alexey A., Sunyaev, Shamil R., Zhang, Guojie, Krogh, Anders, Wang, Jun, Gladyshev, Vadim N.
Publicado 2013

Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma

por Nguyen, Phuong H. D., Ma, Siming, Phua, Cheryl Z. J., Kaya, Neslihan A., Lai, Hannah L. H., Lim, Chun Jye, Lim, Jia Qi, Wasser, Martin, Lai, Liyun, Tam, Wai Leong, Lim, Tony K. H., Wan, Wei Keat, Loh, Tracy, Leow, Wei Qiang, Pang, Yin Huei, Chan, Chung Yip, Lee, Ser Yee, Cheow, Peng Chung, Toh, Han Chong, Ginhoux, Florent, Iyer, Shridhar, Kow, Alfred W. C., Young Dan, Yock, Chung, Alexander, Goh, Brian K. P., Albani, Salvatore, Chow, Pierce K. H., Zhai, Weiwei, Chew, Valerie
Publicado 2021

Author Correction: Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma

por Nguyen, Phuong H. D., Ma, Siming, Phua, Cheryl Z. J., Kaya, Neslihan A., Lai, Hannah L. H., Lim, Chun Jye, Lim, Jia Qi, Wasser, Martin, Lai, Liyun, Tam, Wai Leong, Lim, Tony K. H., Wan, Wei Keat, Loh, Tracy, Leow, Wei Qiang, Pang, Yin Huei, Chan, Chung Yip, Lee, Ser Yee, Cheow, Peng Chung, Toh, Han Chong, Ginhoux, Florent, Iyer, Shridhar, Kow, Alfred W. C., Young Dan, Yock, Chung, Alexander, Bonney, Glen K., Goh, Brian K. P., Albani, Salvatore, Chow, Pierce K. H., Zhai, Weiwei, Chew, Valerie
Publicado 2021

Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer

por Loo, Ser Yue, Toh, Li Ping, Xie, William Haowei, Pathak, Elina, Tan, Wilson, Ma, Siming, Lee, May Yin, Shatishwaran, S., Yeo, Joanna Zhen Zhen, Yuan, Ju, Ho, Yin Ying, Peh, Esther Kai Lay, Muniandy, Magendran, Torta, Federico, Chan, Jack, Tan, Tira J., Sim, Yirong, Tan, Veronique, Tan, Benita, Madhukumar, Preetha, Yong, Wei Sean, Ong, Kong Wee, Wong, Chow Yin, Tan, Puay Hoon, Yap, Yoon Sim, Deng, Lih-Wen, Dent, Rebecca, Foo, Roger, Wenk, Markus R., Lee, Soo Chin, Ho, Ying Swan, Lim, Elaine Hsuen, Tam, Wai Leong
Publicado 2021

Trajectory of immune evasion and cancer progression in hepatocellular carcinoma

por Nguyen, Phuong H. D., Wasser, Martin, Tan, Chong Teik, Lim, Chun Jye, Lai, Hannah L. H., Seow, Justine Jia Wen, DasGupta, Ramanuj, Phua, Cheryl Z. J., Ma, Siming, Yang, Jicheng, Suthen, Sheena D/O, Tam, Wai Leong, Lim, Tony K. H., Yeong, Joe, Leow, Wei Qiang, Pang, Yin Huei, Soon, Gwyneth, Loh, Tracy Jiezhen, Wan, Wei Keat, Chan, Chung Yip, Cheow, Peng Chung, Toh, Han Chong, Kow, Alfred, Dan, Yock Young, Kam, Juinn Huar, Iyer, Shridhar, Madhavan, Krishnakumar, Chung, Alexander, Bonney, Glenn K., Goh, Brian K. P., Fu, Naiyang, Yu, Victor C., Zhai, Weiwei, Albani, Salvatore, Chow, Pierce K. H., Chew, Valerie
Publicado 2022