Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors

por Dernovšek, Jaka, Zajec, Živa, Durcik, Martina, Mašič, Lucija Peterlin, Gobec, Martina, Zidar, Nace, Tomašič, Tihomir
Publicado 2021

Efficient Synthesis of Hydroxy-Substituted 2-Aminobenzo[d]thiazole-6-carboxylic Acid Derivatives as New Building Blocks in Drug Discovery

por Durcik, Martina, Toplak, Žan, Zidar, Nace, Ilaš, Janez, Zega, Anamarija, Kikelj, Danijel, Mašič, Lucija Peterlin, Tomašič, Tihomir
Publicado 2020

Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation

por Durcik, Martina, Skok, Žiga, Ilaš, Janez, Zidar, Nace, Zega, Anamarija, Szili, Petra Éva, Draskovits, Gábor, Révész, Tamás, Kikelj, Danijel, Nyerges, Akos, Pál, Csaba, Mašič, Lucija Peterlin, Tomašič, Tihomir
Publicado 2020

3D Pharmacophore-Based Discovery of Novel K(V)10.1 Inhibitors with Antiproliferative Activity

por Toplak, Žan, Hendrickx, Louise Antonia, Gubič, Špela, Možina, Štefan, Žegura, Bojana, Štern, Alja, Novak, Matjaž, Shi, Xiaoyi, Peigneur, Steve, Tytgat, Jan, Tomašič, Tihomir, Pardo, Luis A., Mašič, Lucija Peterlin
Publicado 2021

Design of New Potent and Selective Thiophene-Based K(V)1.3 Inhibitors and Their Potential for Anticancer Activity

por Gubič, Špela, Hendrickx, Louise Antonia, Shi, Xiaoyi, Toplak, Žan, Možina, Štefan, Theemsche, Kenny M. Van, Pinheiro-Junior, Ernesto Lopes, Peigneur, Steve, Labro, Alain J., Pardo, Luis A., Tytgat, Jan, Tomašič, Tihomir, Mašič, Lucija Peterlin
Publicado 2022

Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

por Skok, Žiga, Barančoková, Michaela, Benek, Ondřej, Cruz, Cristina Durante, Tammela, Päivi, Tomašič, Tihomir, Zidar, Nace, Mašič, Lucija Peterlin, Zega, Anamarija, Stevenson, Clare E. M., Mundy, Julia E. A., Lawson, David M., Maxwell, Anthony, Kikelj, Danijel, Ilaš, Janez
Publicado 2020

Practical Synthesis and Application of Halogen-Doped Pyrrole Building Blocks

por Cotman, Andrej Emanuel, Guérin, Thomas, Kovačević, Ivana, Benedetto Tiz, Davide, Durcik, Martina, Fulgheri, Federica, Možina, Štefan, Secci, Daniela, Sterle, Maša, Ilaš, Janez, Zega, Anamarija, Zidar, Nace, Mašič, Lucija Peterlin, Tomašič, Tihomir, Leroux, Frédéric R., Hanquet, Gilles, Kikelj, Danijel
Publicado 2021

Exploring the 5-Substituted 2-Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE Pathogens

por Sterle, Maša, Durcik, Martina, Stevenson, Clare E. M., Henderson, Sara R., Szili, Petra Eva, Czikkely, Marton, Lawson, David M., Maxwell, Anthony, Cahard, Dominique, Kikelj, Danijel, Zidar, Nace, Pal, Csaba, Mašič, Lucija Peterlin, Ilaš, Janez, Tomašič, Tihomir, Cotman, Andrej Emanuel, Zega, Anamarija
Publicado 2023

Rational design of balanced dual-targeting antibiotics with limited resistance

por Nyerges, Akos, Tomašič, Tihomir, Durcik, Martina, Revesz, Tamas, Szili, Petra, Draskovits, Gabor, Bogar, Ferenc, Skok, Žiga, Zidar, Nace, Ilaš, Janez, Zega, Anamarija, Kikelj, Danijel, Daruka, Lejla, Kintses, Balint, Vasarhelyi, Balint, Foldesi, Imre, Kata, Diána, Welin, Martin, Kimbung, Raymond, Focht, Dorota, Mašič, Lucija Peterlin, Pal, Csaba
Publicado 2020

Structure-Function Studies of Sponge-Derived Compounds on the Cardiac Ca(V)3.1 Channel

por Depuydt, Anne-Sophie, Patel, Piyush A., Toplak, Žan, Bhat, Chinmaya, Voráčová, Manuela, Eteläinen, Irene, Vitulano, Fiammetta, Bruun, Tanja, Lempinen, Antti, Hribernik, Nives, Mäki-Lohiluoma, Eero, Hendrickx, Louise, Pinheiro-Junior, Ernesto Lopes, Tomašič, Tihomir, Mašič, Lucija Peterlin, Yli-Kauhaluoma, Jari, Kiuru, Paula, Tytgat, Jan, Peigneur, Steve
Publicado 2023

Garbage in, garbage out: how reliable training data improved a virtual screening approach against SARS-CoV-2 MPro

por Ruatta, Santiago M., Prada Gori, Denis N., Fló Díaz, Martín, Lorenzelli, Franca, Perelmuter, Karen, Alberca, Lucas N., Bellera, Carolina L., Medeiros, Andrea, López, Gloria V., Ingold, Mariana, Porcal, Williams, Dibello, Estefanía, Ihnatenko, Irina, Kunick, Conrad, Incerti, Marcelo, Luzardo, Martín, Colobbio, Maximiliano, Ramos, Juan Carlos, Manta, Eduardo, Minini, Lucía, Lavaggi, María Laura, Hernández, Paola, Šarlauskas, Jonas, Huerta García, César Sebastian, Castillo, Rafael, Hernández-Campos, Alicia, Ribaudo, Giovanni, Zagotto, Giuseppe, Carlucci, Renzo, Medrán, Noelia S., Labadie, Guillermo R., Martinez-Amezaga, Maitena, Delpiccolo, Carina M. L., Mata, Ernesto G., Scarone, Laura, Posada, Laura, Serra, Gloria, Calogeropoulou, Theodora, Prousis, Kyriakos, Detsi, Anastasia, Cabrera, Mauricio, Alvarez, Guzmán, Aicardo, Adrián, Araújo, Verena, Chavarría, Cecilia, Mašič, Lucija Peterlin, Gantner, Melisa E., Llanos, Manuel A., Rodríguez, Santiago, Gavernet, Luciana, Park, Soonju, Heo, Jinyeong, Lee, Honggun, Paul Park, Kyu-Ho, Bollati-Fogolín, Mariela, Pritsch, Otto, Shum, David, Talevi, Alan, Comini, Marcelo A.
Publicado 2023