Optimized Protocol for Isolation of Small Extracellular Vesicles from Human and Murine Lymphoid Tissues

por Bordas, Marie, Genard, Géraldine, Ohl, Sibylle, Nessling, Michelle, Richter, Karsten, Roider, Tobias, Dietrich, Sascha, Maaß, Kendra K., Seiffert, Martina
Publicado 2020

Evaluation of Storage Tubes for Combined Analysis of Circulating Nucleic Acids in Liquid Biopsies

por Ward Gahlawat, Aoife, Lenhardt, Judith, Witte, Tania, Keitel, Denise, Kaufhold, Anna, Maass, Kendra K, Pajtler, Kristian W, Sohn, Christof, Schott, Sarah
Publicado 2019

EPEN-44. EXTRACELLULAR VESICLES OF SUPRATENTORIAL EPENDYMOMA RELA MEDIATE INTERACTIONS WITH CELLS OF THE TUMOR MICROENVIRONMENT

por Maass, Kendra K, Roosen, Mieke, Benzel, Julia, Wedig, Tatjana, Statz, Britta, Mueller, Torsten, Kalxdorf, Mathias, Krijgsveld, Jeroen, Pfister, Stefan M, Pajtler, Kristian W
Publicado 2020

EPEN-28. Oncogenic dependency of pediatric ependymomas on extracellular vesicle pathways

por Maass, Kendra K, Roosen, Mieke M, Mueller, Torsten, Senfter, Daniel, Benzel, Julia, Wedig, Tatjana, Kalxsdorf, Mathias, Krijgsveld, Jeroen, Pfister, Stefan M, Pajtler, Kristian W
Publicado 2022

From Sampling to Sequencing: A Liquid Biopsy Pre-Analytic Workflow to Maximize Multi-Layer Genomic Information from a Single Tube

por Maass, Kendra K., Schad, Paulina S., Finster, Agnes M. E., Puranachot, Pitithat, Rosing, Fabian, Wedig, Tatjana, Schwarz, Nathalie, Stumpf, Natalie, Pfister, Stefan M., Pajtler, Kristian W.
Publicado 2021

EPEN-12. COMPARING CELLULAR HIERARCHIES AND SPATIAL ARCHITECTURE ACROSS MOLECULAR SUBGROUPS OF SUPRATENTORIAL EPENDYMOMAS

por Jeong, Daeun, Maass, Kendra K, Ghasemi, David R, Englinger, Bernhard, Jiang, Li, Nascimento, Andrezza, Hack, Olivia A, Shaw, McKenzie L, Pfister, Stefan M, Kool, Marcel, Gojo, Johannes, Pajtler *, Kristian W, Filbin *, Mariella G
Publicado 2023

MBRS-68. SINGLE NUCLEUS RNA-SEQUENCING DECIPHERS INTRATUMORAL HETEROGENEITY IN MEDULLOBLASTOMA WITH EXTENSIVE NODULARITY (MBEN)

por Ghasemi, David N, Okonechnikov, Konstantin, Malm, Jan-Philipp, Lappalainen, Kati, Bauer, Katharina, Liberio, Michelle S, Giese, Laura, Maass, Kendra K, Kool, Marcel, Jones, David T W, von Deimling, Andreas, Pfister, Stefan M, Korshunov, Andrey, Pajtler, Kristian W
Publicado 2020

MODL-04. Drug screening in Disorders with Abnormal DNA Damage Response/Repair (DADDR) andin vivo validation

por Kolodziejczak, Anna, Selt, Florian, Peterziel, Heike, Jamaladdin, Nora, Mack, Norman, Maass, Kendra, Kool, Marcel, Herold-Mende, Christel, El Damaty, Ahmed, Oehme, Ina, Jones, David T W, Witt, Olaf, Pajtler, Kristian W, Kratz, Christian, Pfister, Stefan M, Milde, Till
Publicado 2022

PTPRD and CNTNAP2 as markers of tumor aggressiveness in oligodendrogliomas

por Rautajoki, Kirsi J., Jaatinen, Serafiina, Tiihonen, Aliisa M., Annala, Matti, Vuorinen, Elisa M., Kivinen, Anni, Rauhala, Minna J., Maass, Kendra K., Pajtler, Kristian W., Yli-Harja, Olli, Helén, Pauli, Haapasalo, Joonas, Haapasalo, Hannu, Zhang, Wei, Nykter, Matti
Publicado 2022

EPEN-03. ZFTA/C11ORF95 FUSIONS DRIVE SUPRATENTORIAL EPENDYMOMA VIA SHARED ONCOGENIC MECHANISMS

por Zheng, Tuyu, Ghasemi, David R, Okonechnikov, Konstantin, Korshunov, Andrey, Maaß, Kendra K, Sill, Martin, Gojo, Johannes, Schüller, Ulrich, Milde, Till, Mack, Stephen C, Gilbertson, Richard J, von Deimling, Andreas, Jones, David T W, Kool, Marcel, Pfister, Stefan M, Sahm, Felix, Kawauchi, Daisuke, Pajtler, Kristian W
Publicado 2021

EPEN-23. Interaction of epigenetic regulation and telomerase re-activation in high-risk ependymoma

por Jaunecker, Carola N, Kirchhofer, Dominik, Madlener, Sibylle, Laemmerer, Anna, Gabler, Lisa, Pirker, Christine, Piontek, Martin, Maaß, Kendra, Okonechnikov, Konstanitin, Englinger, Bernhard, Jiang, Li, Mayr, Lisa, Senfter, Daniel, Spiegl-Kreinecker, Sabine, Stepien, Natalia, Dorfer, Christian, Filbin, Mariella, Kool, Marcel, Gojo, Johannes, Berger, Walter, Loetsch-Gojo, Daniela
Publicado 2022

Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting

por Rautajoki, Kirsi J., Jaatinen, Serafiina, Hartewig, Anja, Tiihonen, Aliisa M., Annala, Matti, Salonen, Iida, Valkonen, Masi, Simola, Vili, Vuorinen, Elisa M., Kivinen, Anni, Rauhala, Minna J., Nurminen, Riikka, Maass, Kendra K., Lahtela, Sirpa-Liisa, Jukkola, Arja, Yli-Harja, Olli, Helén, Pauli, Pajtler, Kristian W., Ruusuvuori, Pekka, Haapasalo, Joonas, Zhang, Wei, Haapasalo, Hannu, Nykter, Matti
Publicado 2023

EPEN-18. CROSS-SPECIES GENOMICS IDENTIFIES GLI2 AS AN ONCOGENE OF C11orf95 FUSION-POSITIVE SUPRATENTORIAL EPENDYMOMA

por Zheng, Tuyu, Ghasemi, David R, Okonechnikov, Konstantin, Korshunov, Andrey, Sill, Martin, Hübner, Jens-Martin, Maaß, Kendra K, Snuderl, Matija, Gojo, Johannes, Schüller, Ulrich, Gerber, Nicolas U, Hernáiz-Driever, Pablo, Milde, Till, Sturm, Dominik, Chapman, Rebecca, Grundy, Richard G, von Deimling, Andreas, Jones, David T W, Kool, Marcel, Pfister, Stefan M, Sahm, Felix, Kawauchi, Daisuke, Pajtler, Kristian W
Publicado 2020

MEDB-74. Serial assessment of measurable residual disease in medulloblastoma liquid biopsies

por Northcott, Paul, Smith, Kyle, Kumar, Rahul, Paul, Leena, Bihannic, Laure, Lin, Tong, Maass, Kendra, Pajtler, Kristian, Chintagumpala, Murali, Su, Jack, Bouffet, Eric, Fisher, Michael, Gururangan, Sridharan, Cohn, Richard, Hassall, Tim, Hansford, Jordan, Klimo, Paul, Boop, Frederick, Stewart, Clinton, Harreld, Julie, Merchant, Thomas, Tatevossian, Ruth, Neale, Geoffrey, Lear, Matthew, Klco, Jeffery, Orr, Brent, Ellison, David, Gilbertson, Richard, Onar-Thomas, Arzu, Gajjar, Amar, Robinson, Giles
Publicado 2022

MYCN amplification drives an aggressive form of spinal ependymoma

por Ghasemi, David R., Sill, Martin, Okonechnikov, Konstantin, Korshunov, Andrey, Yip, Stephen, Schutz, Peter W., Scheie, David, Kruse, Anders, Harter, Patrick N., Kastelan, Marina, Wagner, Marlies, Hartmann, Christian, Benzel, Julia, Maass, Kendra K., Khasraw, Mustafa, Sträter, Ronald, Thomas, Christian, Paulus, Werner, Kratz, Christian P., Witt, Hendrik, Kawauchi, Daisuke, Herold-Mende, Christel, Sahm, Felix, Brandner, Sebastian, Kool, Marcel, Jones, David T. W., von Deimling, Andreas, Pfister, Stefan M., Reuss, David E., Pajtler, Kristian W.
Publicado 2019

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis

por Pajtler, Kristian W., Wei, Yiju, Okonechnikov, Konstantin, Silva, Patricia B. G., Vouri, Mikaella, Zhang, Lei, Brabetz, Sebastian, Sieber, Laura, Gulley, Melissa, Mauermann, Monika, Wedig, Tatjana, Mack, Norman, Imamura Kawasawa, Yuka, Sharma, Tanvi, Zuckermann, Marc, Andreiuolo, Felipe, Holland, Eric, Maass, Kendra, Körkel-Qu, Huiqin, Liu, Hai-Kun, Sahm, Felix, Capper, David, Bunt, Jens, Richards, Linda J., Jones, David T. W., Korshunov, Andrey, Chavez, Lukas, Lichter, Peter, Hoshino, Mikio, Pfister, Stefan M., Kool, Marcel, Li, Wei, Kawauchi, Daisuke
Publicado 2019

Targeting fibroblast growth factor receptors to combat aggressive ependymoma

por Lötsch, Daniela, Kirchhofer, Dominik, Englinger, Bernhard, Jiang, Li, Okonechnikov, Konstantin, Senfter, Daniel, Laemmerer, Anna, Gabler, Lisa, Pirker, Christine, Donson, Andrew M., Bannauer, Peter, Korbel, Pia, Jaunecker, Carola N., Hübner, Jens-Martin, Mayr, Lisa, Madlener, Sibylle, Schmook, Maria T., Ricken, Gerda, Maaß, Kendra, Grusch, Michael, Holzmann, Klaus, Grasl-Kraupp, Bettina, Spiegl-Kreinecker, Sabine, Hsu, Jennifer, Dorfer, Christian, Rössler, Karl, Azizi, Amedeo A., Foreman, Nicholas K., Peyrl, Andreas, Haberler, Christine, Czech, Thomas, Slavc, Irene, Filbin, Mariella G., Pajtler, Kristian W., Kool, Marcel, Berger, Walter, Gojo, Johannes
Publicado 2021

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

por Sievers, Philipp, Henneken, Sophie C., Blume, Christina, Sill, Martin, Schrimpf, Daniel, Stichel, Damian, Okonechnikov, Konstantin, Reuss, David E., Benzel, Julia, Maaß, Kendra K., Kool, Marcel, Sturm, Dominik, Zheng, Tuyu, Ghasemi, David R., Kohlhof-Meinecke, Patricia, Cruz, Ofelia, Suñol, Mariona, Lavarino, Cinzia, Ruf, Viktoria, Boldt, Henning B., Pagès, Mélanie, Pouget, Celso, Schweizer, Leonille, Kranendonk, Mariëtte E. G., Akhtar, Noreen, Bunkowski, Stephanie, Stadelmann , Christine, Schüller, Ulrich, Mueller, Wolf C., Dohmen, Hildegard, Acker, Till, Harter, Patrick N., Mawrin, Christian, Beschorner, Rudi, Brandner, Sebastian, Snuderl, Matija, Abdullaev, Zied, Aldape, Kenneth, Gilbert, Mark R., Armstrong, Terri S., Ellison, David W., Capper, David, Ichimura, Koichi, Reifenberger, Guido, Grundy, Richard G., Jabado, Nada, Krskova, Lenka, Zapotocky, Michal, Vicha, Ales, Varlet, Pascale, Wesseling, Pieter, Rutkowski, Stefan, Korshunov, Andrey, Wick, Wolfgang, Pfister, Stefan M., Jones, David T. W., von Deimling, Andreas, Pajtler, Kristian W., Sahm, Felix
Publicado 2021