Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers

por Wang, Shijie, Liu, Zhiyong, Ye, Tao, Mabrouk, Omar S., Maltbie, Tyler, Aasly, Jan, West, Andrew B.
Publicado 2017

Quantitative Measurements of LRRK2 in Human Cerebrospinal Fluid Demonstrates Increased Levels in G2019S Patients

por Mabrouk, Omar S., Chen, Siwei, Edwards, Amanda L., Yang, Minhua, Hirst, Warren D., Graham, Danielle L.
Publicado 2020

Pharmacological and Behavioral Characterization of D-473, an Orally Active Triple Reuptake Inhibitor Targeting Dopamine, Serotonin and Norepinephrine Transporters

por Dutta, Aloke K., Santra, Soumava, Sharma, Horrick, Voshavar, Chandrashekhar, Xu, Liping, Mabrouk, Omar, Antonio, Tamara, Reith, Maarten E. A.
Publicado 2014

Mesolimbic Dopamine Signals the Value of Work

por Hamid, Arif A., Pettibone, Jeffrey R., Mabrouk, Omar S., Hetrick, Vaughn L., Schmidt, Robert, Vander Weele, Caitlin M., Kennedy, Robert T., Aragona, Brandon J., Berke, Joshua D.
Publicado 2015

The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson’s Disease

por Rideout, Hardy J., Chartier-Harlin, Marie-Christine, Fell, Matthew J., Hirst, Warren D., Huntwork-Rodriguez, Sarah, Leyns, Cheryl E. G., Mabrouk, Omar S., Taymans, Jean-Marc
Publicado 2020

In vivo detection of optically-evoked opioid peptide release

por Al-Hasani, Ream, Wong, Jenny-Marie T, Mabrouk, Omar S, McCall, Jordan G, Schmitz, Gavin P, Porter-Stransky, Kirsten A, Aragona, Brandon J, Kennedy, Robert T, Bruchas, Michael R
Publicado 2018

Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons

por Pappas, Samuel S, Darr, Katherine, Holley, Sandra M, Cepeda, Carlos, Mabrouk, Omar S, Wong, Jenny-Marie T, LeWitt, Tessa M, Paudel, Reema, Houlden, Henry, Kennedy, Robert T, Levine, Michael S, Dauer, William T
Publicado 2015

The Delta-Specific Opioid Glycopeptide BBI-11008: CNS Penetration and Behavioral Analysis in a Preclinical Model of Levodopa-Induced Dyskinesia

por Bartlett, Mitchell J., Mabrouk, Omar S., Szabò, Lajos, Flores, Andrew J., Parent, Kate L., Bidlack, Jean M., Heien, Michael L., Kennedy, Robert T., Polt, Robin, Sherman, Scott J., Falk, Torsten
Publicado 2020

Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice

por Longo, Francesco, Mercatelli, Daniela, Novello, Salvatore, Arcuri, Ludovico, Brugnoli, Alberto, Vincenzi, Fabrizio, Russo, Isabella, Berti, Giulia, Mabrouk, Omar S., Kennedy, Robert T., Shimshek, Derya R., Varani, Katia, Bubacco, Luigi, Greggio, Elisa, Morari, Michele
Publicado 2017

Glucocerebrosidase Activity is not Associated with Parkinson's Disease Risk or Severity

por Omer, Nurit, Giladi, Nir, Gurevich, Tanya, Bar‐Shira, Anat, Gana‐Weisz, Mali, Glinka, Tal, Goldstein, Orly, Kestenbaum, Meir, Cedarbaum, Jesse M., Mabrouk, Omar S., Fraser, Kyle B., Shirvan, Julia C., Orr‐Urtreger, Avi, Mirelman, Anat, Thaler, Avner
Publicado 2021