Chemical genomics: what will it take and who gets to play?

por MacBeath, Gavin
Publicado 2001

A System-Wide Investigation of the Dynamics of Wnt Signaling Reveals Novel Phases of Transcriptional Regulation

por Gujral, Taranjit S., MacBeath, Gavin
Publicado 2010

High- and Low-Affinity Epidermal Growth Factor Receptor-Ligand Interactions Activate Distinct Signaling Pathways

por Krall, Jordan A., Beyer, Elsa M., MacBeath, Gavin
Publicado 2011

An integrated approach to prognosis using protein microarrays and nonparametric methods

por Knickerbocker, Tanya, Chen, Jiunn R, Thadhani, Ravi, MacBeath, Gavin
Publicado 2007

A multiscale statistical mechanical framework integrates biophysical and genomic data to assemble cancer networks

por AlQuraishi, Mohammed, Koytiger, Grigoriy, Jenney, Anne, MacBeath, Gavin, Sorger, Peter K.
Publicado 2014

Phase 1 dose escalation study of seribantumab (MM-121), an anti-HER3 monoclonal antibody, in patients with advanced solid tumors

por Denlinger, Crystal S., Keedy, Vicki L., Moyo, Victor, MacBeath, Gavin, Shapiro, Geoffrey I.
Publicado 2021

Estimation of immune cell content in tumour tissue using single-cell RNA-seq data

por Schelker, Max, Feau, Sonia, Du, Jinyan, Ranu, Nav, Klipp, Edda, MacBeath, Gavin, Schoeberl, Birgit, Raue, Andreas
Publicado 2017

Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1

por Mehlitz, Adrian, Banhart, Sebastian, Mäurer, André P., Kaushansky, Alexis, Gordus, Andrew G., Zielecki, Julia, MacBeath, Gavin, Meyer, Thomas F.
Publicado 2010

Tyrosine-Phosphorylated Caveolin-1 Blocks Bacterial Uptake by Inducing Vav2-RhoA-Mediated Cytoskeletal Rearrangements

por Boettcher, Jan Peter, Kirchner, Marieluise, Churin, Yuri, Kaushansky, Alexis, Pompaiah, Malvika, Thorn, Hans, Brinkmann, Volker, MacBeath, Gavin, Meyer, Thomas F.
Publicado 2010

Linear combinations of docking affinities explain quantitative differences in RTK signaling

por Gordus, Andrew, Krall, Jordan A, Beyer, Elsa M, Kaushansky, Alexis, Wolf-Yadlin, Alejandro, Sevecka, Mark, Chang, Bryan H, Rush, John, MacBeath, Gavin
Publicado 2009

Predicting ligand-dependent tumors from multi-dimensional signaling features

por Hass, Helge, Masson, Kristina, Wohlgemuth, Sibylle, Paragas, Violette, Allen, John E., Sevecka, Mark, Pace, Emily, Timmer, Jens, Stelling, Joerg, MacBeath, Gavin, Schoeberl, Birgit, Raue, Andreas
Publicado 2017

Unbiased Screens Show CD8(+) T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein

por Ferretti, Andrew P., Kula, Tomasz, Wang, Yifan, Nguyen, Dalena M.V., Weinheimer, Adam, Dunlap, Garrett S., Xu, Qikai, Nabilsi, Nancy, Perullo, Candace R., Cristofaro, Alexander W., Whitton, Holly J., Virbasius, Amy, Olivier, Kenneth J., Buckner, Lyndsey R., Alistar, Angela T., Whitman, Eric D., Bertino, Sarah A., Chattopadhyay, Shrikanta, MacBeath, Gavin
Publicado 2020

Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121)

por Schoeberl, Birgit, Kudla, Art, Masson, Kristina, Kalra, Ashish, Curley, Michael, Finn, Gregory, Pace, Emily, Harms, Brian, Kim, Jaeyeon, Kearns, Jeff, Fulgham, Aaron, Burenkova, Olga, Grantcharova, Viara, Yarar, Defne, Paragas, Violette, Fitzgerald, Jonathan, Wainszelbaum, Marisa, West, Kip, Mathews, Sara, Nering, Rachel, Adiwijaya, Bambang, Garcia, Gabriela, Kubasek, Bill, Moyo, Victor, Czibere, Akos, Nielsen, Ulrik B, MacBeath, Gavin
Publicado 2017