Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host Disease

por Hippen, Keli L., Loschi, Michael, Nicholls, Jemma, MacDonald, Kelli P. A., Blazar, Bruce R.
Publicado 2018

Selectivity matters: selective ROCK2 inhibitor ameliorates established liver fibrosis via targeting inflammation, fibrosis, and metabolism

por Zanin-Zhorov, Alexandra, Chen, Wei, Moretti, Julien, Nyuydzefe, Melanie S., Zhorov, Iris, Munshi, Rashmi, Ghosh, Malavika, Serdjebi, Cindy, MacDonald, Kelli, Blazar, Bruce R., Palmer, Melissa, Waksal, Samuel D.
Publicado 2023

VCAM-1 and VLA-4 Modulate Dendritic Cell IL-12p40 Production in Experimental Visceral Leishmaniasis

por Stanley, Amanda C., Dalton, Jane E., Rossotti, Susanna H., MacDonald, Kelli P., Zhou, Yonghong, Rivera, Fabian, Schroder, Wayne A., Maroof, Asher, Hill, Geoff R., Kaye, Paul M., Engwerda, Christian R.
Publicado 2008

Donor bone marrow–derived macrophage MHC II drives neuroinflammation and altered behavior during chronic GVHD in mice

por Adams, Rachael C., Carter-Cusack, Dylan, Shaikh, Samreen N., Llanes, Genesis T., Johnston, Rebecca L., Quaife-Ryan, Gregory, Boyle, Glen, Koufariotis, Lambros T., Möller, Andreas, Blazar, Bruce R., Vukovic, Jana, MacDonald, Kelli P. A.
Publicado 2022

The liver contains distinct interconnected networks of CX3CR1 (+) macrophages, XCR1 (+) type 1 and CD301a (+) type 2 conventional dendritic cells embedded within portal tracts

por English, Kieran, Tan, Sioh Yang, Kwan, Rain, Holz, Lauren E, Sierro, Frederic, McGuffog, Claire, Kaisho, Tsuneyasu, Heath, William R, MacDonald, Kelli PA, McCaughan, Geoffrey W, Bowen, David G, Bertolino, Patrick
Publicado 2022

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

por Irvine, Katharine M., Clouston, Andrew D., Gadd, Victoria L., Miller, Gregory C., Wong, Weng-Yew, Melino, Michelle, Maradana, Muralidhara Rao, MacDonald, Kelli, Lang, Richard A., Sweet, Matthew J., Blumenthal, Antje, Powell, Elizabeth E.
Publicado 2015

Chronic GvHD NIH Consensus Project Biology Task Force: evolving path to personalized treatment of chronic GvHD

por Buxbaum, Nataliya P., Socié, Gerard, Hill, Geoffrey R., MacDonald, Kelli P. A., Tkachev, Victor, Teshima, Takanori, Lee, Stephanie J., Ritz, Jerome, Sarantopoulos, Stefanie, Luznik, Leo, Zeng, Defu, Paczesny, Sophie, Martin, Paul J., Pavletic, Steven Z., Schultz, Kirk R., Blazar, Bruce R.
Publicado 2022

ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis

por Nalkurthi, Christina, Schroder, Wayne A., Melino, Michelle, Irvine, Katharine M., Nyuydzefe, Melanie, Chen, Wei, Liu, Jing, Teng, Michele W.L., Hill, Geoffrey R., Bertolino, Patrick, Blazar, Bruce R., Miller, Gregory C., Clouston, Andrew D., Zanin-Zhorov, Alexandra, MacDonald, Kelli P.A.
Publicado 2021

Bone marrow-derived and resident liver macrophages display unique transcriptomic signatures but similar biological functions

por Beattie, Lynette, Sawtell, Amy, Mann, Jason, Frame, Teija C.M., Teal, Bianca, de Labastida Rivera, Fabian, Brown, Najmeeyah, Walwyn-Brown, Katherine, Moore, John W.J., MacDonald, Sandy, Lim, Eng-Kiat, Dalton, Jane E., Engwerda, Christian R., MacDonald, Kelli P., Kaye, Paul M.
Publicado 2016

An atypical role for the myeloid receptor Mincle in central nervous system injury

por Arumugam, Thiruma V, Manzanero, Silvia, Furtado, Milena, Biggins, Patrick J, Hsieh, Yu-Hsuan, Gelderblom, Mathias, MacDonald, Kelli PA, Salimova, Ekaterina, Li, Yu-I, Korn, Othmar, Dewar, Deborah, Macrae, I Mhairi, Ashman, Robert B, Tang, Sung-Chun, Rosenthal, Nadia A, Ruitenberg, Marc J, Magnus, Tim, Wells, Christine A
Publicado 2016

Therapeutic potential of macrophage colony-stimulating factor in chronic liver disease

por Keshvari, Sahar, Genz, Berit, Teakle, Ngari, Caruso, Melanie, Cestari, Michelle F., Patkar, Omkar L., Tse, Brian W. C., Sokolowski, Kamil A., Ebersbach, Hilmar, Jascur, Julia, MacDonald, Kelli P. A., Miller, Gregory, Ramm, Grant A., Pettit, Allison R., Clouston, Andrew D., Powell, Elizabeth E., Hume, David A., Irvine, Katharine M.
Publicado 2022

CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells

por Kara, Ervin E., McKenzie, Duncan R., Bastow, Cameron R., Gregor, Carly E., Fenix, Kevin A., Ogunniyi, Abiodun D., Paton, James C., Mack, Matthias, Pombal, Diana R., Seillet, Cyrill, Dubois, Bénédicte, Liston, Adrian, MacDonald, Kelli P. A., Belz, Gabrielle T., Smyth, Mark J., Hill, Geoffrey R., Comerford, Iain, McColl, Shaun R.
Publicado 2015

Bone Marrow Regulatory T Cells Are a Unique Population, Supported by Niche-Specific Cytokines and Plasmacytoid Dendritic Cells, and Required for Chronic Graft-Versus-Host Disease C...

por Nicholls, Jemma, Cao, Benjamin, Le Texier, Laetitia, Xiong, Laura Yan, Hunter, Christopher R., Llanes, Genesis, Aguliar, Ethan G., Schroder, Wayne A., Phipps, Simon, Lynch, Jason P., Cao, Huimin, Heazlewood, Shen Y., Williams, Brenda, Clouston, Andrew D., Nefzger, Christian M., Polo, Jose M., Nilsson, Susan K., Blazar, Bruce R., MacDonald, Kelli P. A.
Publicado 2021

Donor colonic CD103(+) dendritic cells determine the severity of acute graft-versus-host disease

por Koyama, Motoko, Cheong, Melody, Markey, Kate A., Gartlan, Kate H., Kuns, Rachel D., Locke, Kelly R., Lineburg, Katie E., Teal, Bianca E., Leveque-El mouttie, Lucie, Bunting, Mark D., Vuckovic, Slavica, Zhang, Ping, Teng, Michele W.L., Varelias, Antiopi, Tey, Siok-Keen, Wockner, Leesa F., Engwerda, Christian R., Smyth, Mark J., Belz, Gabrielle T., McColl, Shaun R., MacDonald, Kelli P.A., Hill, Geoffrey R.
Publicado 2015

BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection

por Mills, Richard J., Humphrey, Sean J., Fortuna, Patrick R.J., Lor, Mary, Foster, Simon R., Quaife-Ryan, Gregory A., Johnston, Rebecca L., Dumenil, Troy, Bishop, Cameron, Rudraraju, Rajeev, Rawle, Daniel J., Le, Thuy, Zhao, Wei, Lee, Leo, Mackenzie-Kludas, Charley, Mehdiabadi, Neda R., Halliday, Christopher, Gilham, Dean, Fu, Li, Nicholls, Stephen J., Johansson, Jan, Sweeney, Michael, Wong, Norman C.W., Kulikowski, Ewelina, Sokolowski, Kamil A., Tse, Brian W.C., Devilée, Lynn, Voges, Holly K., Reynolds, Liam T., Krumeich, Sophie, Mathieson, Ellen, Abu-Bonsrah, Dad, Karavendzas, Kathy, Griffen, Brendan, Titmarsh, Drew, Elliott, David A., McMahon, James, Suhrbier, Andreas, Subbarao, Kanta, Porrello, Enzo R., Smyth, Mark J., Engwerda, Christian R., MacDonald, Kelli P.A., Bald, Tobias, James, David E., Hudson, James E.
Publicado 2021