Huntington's disease: the case for genetic modifiers

por Gusella, James F, MacDonald, Marcy E
Publicado 2009

An over-expression system for characterizing Ppt1 function in Drosophila

por Korey, Christopher A, MacDonald, Marcy E
Publicado 2003

Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation

por Wang, Jin, Gines, Silvia, MacDonald, Marcy E, Gusella, James F
Publicado 2005

Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo

por Woda, Juliana M, Calzonetti, Teresa, Hilditch-Maguire, Paige, Duyao, Mabel P, Conlon, Ronald A, MacDonald, Marcy E
Publicado 2005

Genetic analysis of the GRIK2 modifier effect in Huntington's disease

por Zeng, Wenqi, Gillis, Tammy, Hakky, Michael, Djoussé, Luc, Myers, Richard H, MacDonald, Marcy E, Gusella, James F
Publicado 2006

Deficiency of Huntingtin Has Pleiotropic Effects in the Social Amoeba Dictyostelium discoideum

por Myre, Michael A., Lumsden, Amanda L., Thompson, Morgan N., Wasco, Wilma, MacDonald, Marcy E., Gusella, James F.
Publicado 2011

Unbiased Gene Expression Analysis Implicates the huntingtin Polyglutamine Tract in Extra-mitochondrial Energy Metabolism

por Lee, Jong-Min, Ivanova, Elena V, Seong, Ihn Sik, Cashorali, Tanya, Kohane, Isaac, Gusella, James F, MacDonald, Marcy E
Publicado 2007

Distinct Early Molecular Responses to Mutations Causing vLINCL and JNCL Presage ATP Synthase Subunit C Accumulation in Cerebellar Cells

por Cao, Yi, Staropoli, John F., Biswas, Sunita, Espinola, Janice A., MacDonald, Marcy E., Lee, Jong-Min, Cotman, Susan L.
Publicado 2011

Hdh(Q111) Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation

por Carroll, Jeffrey B., Deik, Amy, Fossale, Elisa, Weston, Rory M., Guide, Jolene R., Arjomand, Jamshid, Kwak, Seung, Clish, Clary B., MacDonald, Marcy E.
Publicado 2015

Chromosome substitution strain assessment of a Huntington’s disease modifier locus

por Ramos, Eliana Marisa, Kovalenko, Marina, Guide, Jolene R., St. Claire, Jason, Gillis, Tammy, Mysore, Jayalakshmi S., Sequeiros, Jorge, Wheeler, Vanessa C., Alonso, Isabel, MacDonald, Marcy E.
Publicado 2015

Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis

por Fossale, Elisa, Wolf, Pavlina, Espinola, Janice A, Lubicz-Nawrocka, Tanya, Teed, Allison M, Gao, Hanlin, Rigamonti, Dorotea, Cattaneo, Elena, MacDonald, Marcy E, Cotman, Susan L
Publicado 2004

HD CAGnome: A Search Tool for Huntingtin CAG Repeat Length-Correlated Genes

por Galkina, Ekaterina I., Shin, Aram, Coser, Kathryn R., Shioda, Toshi, Kohane, Isaac S., Seong, Ihn Sik, Wheeler, Vanessa C., Gusella, James F., MacDonald, Marcy E., Lee, Jong-Min
Publicado 2014

Huntington’s Disease Pathogenesis: Two Sequential Components

por Hong, Eun Pyo, MacDonald, Marcy E., Wheeler, Vanessa C., Jones, Lesley, Holmans, Peter, Orth, Michael, Monckton, Darren G., Long, Jeffrey D., Kwak, Seung, Gusella, James F., Lee, Jong-Min
Publicado 2021

Haplotype analysis of the 4p16.3 region in Portuguese families with Huntington's disease

por Ramos, Eliana Marisa, Gillis, Tammy, Mysore, Jayalakshmi S., Lee, Jong‐Min, Gögele, Martin, D'Elia, Yuri, Pichler, Irene, Sequeiros, Jorge, Pramstaller, Peter P., Gusella, James F., MacDonald, Marcy E., Alonso, Isabel
Publicado 2015

Timing and Impact of Psychiatric, Cognitive, and Motor Abnormalities in Huntington Disease

por McAllister, Branduff, Gusella, James F., Landwehrmeyer, G. Bernhard, Lee, Jong-Min, MacDonald, Marcy E., Orth, Michael, Rosser, Anne E., Williams, Nigel M., Holmans, Peter, Jones, Lesley, Massey, Thomas H.
Publicado 2021

RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression

por Labadorf, Adam, Hoss, Andrew G., Lagomarsino, Valentina, Latourelle, Jeanne C., Hadzi, Tiffany C., Bregu, Joli, MacDonald, Marcy E., Gusella, James F., Chen, Jiang-Fan, Akbarian, Schahram, Weng, Zhiping, Myers, Richard H.
Publicado 2015

Correction: RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression

por Labadorf, Adam, Hoss, Andrew G., Lagomarsino, Valentina, Latourelle, Jeanne C., Hadzi, Tiffany C., Bregu, Joli, MacDonald, Marcy E., Gusella, James F., Chen, Jiang-Fan, Akbarian, Schahram, Weng, Zhiping, Myers, Richard H.
Publicado 2016

MicroRNAs Located in the Hox Gene Clusters Are Implicated in Huntington's Disease Pathogenesis

por Hoss, Andrew G., Kartha, Vinay K., Dong, Xianjun, Latourelle, Jeanne C., Dumitriu, Alexandra, Hadzi, Tiffany C., MacDonald, Marcy E., Gusella, James F., Akbarian, Schahram, Chen, Jiang-Fan, Weng, Zhiping, Myers, Richard H.
Publicado 2014

Novel DNA Aptamers that Bind to Mutant Huntingtin and Modify Its Activity

por Shin, Baehyun, Jung, Roy, Oh, Hyejin, Owens, Gwen E., Lee, Hyeongseok, Kwak, Seung, Lee, Ramee, Cotman, Susan L., Lee, Jong-Min, MacDonald, Marcy E., Song, Ji-Joon, Vijayvargia, Ravi, Seong, Ihn Sik
Publicado 2018

miR-10b-5p expression in Huntington’s disease brain relates to age of onset and the extent of striatal involvement

por Hoss, Andrew G, Labadorf, Adam, Latourelle, Jeanne C, Kartha, Vinay K, Hadzi, Tiffany C, Gusella, James F, MacDonald, Marcy E, Chen, Jiang-Fan, Akbarian, Schahram, Weng, Zhiping, Vonsattel, Jean Paul, Myers, Richard H
Publicado 2015