Proteinase Activated Receptor 1 Mediated Fibrosis in a Mouse Model of Liver Injury: A Role for Bone Marrow Derived Macrophages

por Kallis, Yiannis N., Scotton, Christopher J., MacKinnon, Alison C., Goldin, Robert D., Wright, Nicholas A., Iredale, John P., Chambers, Rachel C., Forbes, Stuart J.
Publicado 2014

Safety and pharmacokinetics of GB1211, an oral galectin-3 inhibitor: a single- and multiple-dose first-in-human study in healthy participants

por Aslanis, Vassilios, Slack, Robert J., MacKinnon, Alison C., McClinton, Catherine, Tantawi, Susan, Gravelle, Lise, Nilsson, Ulf J., Leffler, Hakon, Brooks, Ashley, Khindri, Sanjeev K., Marshall, Richard P., Pedersen, Anders, Schambye, Hans, Zetterberg, Fredrik
Publicado 2023

Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis

por Hirani, Nikhil, MacKinnon, Alison C., Nicol, Lisa, Ford, Paul, Schambye, Hans, Pedersen, Anders, Nilsson, Ulf J., Leffler, Hakon, Sethi, Tariq, Tantawi, Susan, Gravelle, Lise, Slack, Robert J., Mills, Ross, Karmakar, Utsa, Humphries, Duncan, Zetterberg, Fredrik, Keeling, Lucy, Paul, Lyn, Molyneaux, Philip L., Li, Feng, Funston, Wendy, Forrest, Ian A., Simpson, A. John, Gibbons, Michael A., Maher, Toby M.
Publicado 2021

An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE)

por Gaughan, Erin E., Quinn, Tom M., Mills, Andrew, Bruce, Annya M., Antonelli, Jean, MacKinnon, Alison C., Aslanis, Vassilios, Li, Feng, O’Connor, Richard, Boz, Cecilia, Mills, Ross, Emanuel, Philip, Burgess, Matthew, Rinaldi, Giulia, Valanciute, Asta, Mills, Bethany, Scholefield, Emma, Hardisty, Gareth, Findlay, Emily Gwyer, Parker, Richard A., Norrie, John, Dear, James W., Akram, Ahsan R., Koch, Oliver, Templeton, Kate, Dockrell, David H., Walsh, Timothy S., Partridge, Stephen, Humphries, Duncan, Wang-Jairaj, Jie, Slack, Robert J., Schambye, Hans, Phung, De, Gravelle, Lise, Lindmark, Bertil, Shankar-Hari, Manu, Hirani, Nikhil, Sethi, Tariq, Dhaliwal, Kevin
Publicado 2022