Profiling intermediate cell states in high resolution

por MacLean, Adam L.
Publicado 2022

RVAgene: generative modeling of gene expression time series data

por Mitra, Raktim, MacLean, Adam L
Publicado 2021

A single-cell resolved cell-cell communication model explains lineage commitment in hematopoiesis

por Rommelfanger, Megan K., MacLean, Adam L.
Publicado 2021

Single-cell Ca(2+) parameter inference reveals how transcriptional states inform dynamic cell responses

por Wu, Xiaojun, Wollman, Roy, MacLean, Adam L.
Publicado 2023

Exploring intermediate cell states through the lens of single cells

por MacLean, Adam L., Hong, Tian, Nie, Qing
Publicado 2018

Myeloid-Derived Suppressor–Cell Dynamics Control Outcomes in the Metastatic Niche

por Kreger, Jesse, Roussos Torres, Evanthia T., MacLean, Adam L.
Publicado 2023

Cell lineage and communication network inference via optimization for single-cell transcriptomics

por Wang, Shuxiong, Karikomi, Matthew, MacLean, Adam L, Nie, Qing
Publicado 2019

scEpath: energy landscape-based inference of transition probabilities and cellular trajectories from single-cell transcriptomic data

por Jin, Suoqin, MacLean, Adam L, Peng, Tao, Nie, Qing
Publicado 2018

Population dynamics of normal and leukaemia stem cells in the haematopoietic stem cell niche show distinct regimes where leukaemia will be controlled

por MacLean, Adam L., Lo Celso, Cristina, Stumpf, Michael P. H.
Publicado 2013

Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia

por Crowell, Helena L., MacLean, Adam L., Stumpf, Michael P.H.
Publicado 2016

Cellular population dynamics control the robustness of the stem cell niche

por MacLean, Adam L., Kirk, Paul D. W., Stumpf, Michael P. H.
Publicado 2015

Modeling the effects of EMT-immune dynamics on carcinoma disease progression

por Bergman, Daniel R., Karikomi, Matthew K., Yu, Min, Nie, Qing, MacLean, Adam L.
Publicado 2021

Epithelial-Mesenchymal Transition in Metastatic Cancer Cell Populations Affects Tumor Dormancy in a Simple Mathematical Model

por MacLean, Adam L., Harrington, Heather A., Stumpf, Michael P. H., Hansen, Marc D. H.
Publicado 2014

A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions

por Peng, Tao, Liu, Linan, MacLean, Adam L, Wong, Chi Wut, Zhao, Weian, Nie, Qing
Publicado 2017

Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis

por Lambert, Ben, MacLean, Adam L., Fletcher, Alexander G., Combes, Alexander N., Little, Melissa H., Byrne, Helen M.
Publicado 2018

Gene regulatory network inference with popInfer reveals dynamic regulation of hematopoietic stem cell quiescence upon diet restriction and aging

por Rommelfanger, Megan K., Behrends, Marthe, Chen, Yulin, Martinez, Jonathan, Bens, Martin, Xiong, Lingyun, Rudolph, K. Lenhard, MacLean, Adam L.
Publicado 2023

Single-cell transcriptomic analysis of zebrafish cranial neural crest reveals spatiotemporal regulation of lineage decisions during development

por Tatarakis, David, Cang, Zixuan, Wu, Xiaojun, Sharma, Praveer P., Karikomi, Matthew, MacLean, Adam L., Nie, Qing, Schilling, Thomas F.
Publicado 2021

Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points

por Vainieri, Maria L., Blagborough, Andrew M., MacLean, Adam L., Haltalli, Myriam L. R., Ruivo, Nicola, Fletcher, Helen A., Stumpf, Michael P. H., Sinden, Robert E., Lo Celso, Cristina
Publicado 2016

Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics

por Haensel, Daniel, Jin, Suoqin, Sun, Peng, Cinco, Rachel, Dragan, Morgan, Nguyen, Quy, Cang, Zixuan, Gong, Yanwen, Vu, Remy, MacLean, Adam L., Kessenbrock, Kai, Gratton, Enrico, Nie, Qing, Dai, Xing
Publicado 2020

Direct androgen receptor regulation of sexually dimorphic gene expression in the mammalian kidney

por Xiong, Lingyun, Liu, Jing, Han, Seung Yub, Koppitch, Kari, Guo, Jin-Jin, Rommelfanger, Megan, Gao, Fan, Hallgrimsdottir, Ingileif B., Pachter, Lior, Kim, Junhyong, MacLean, Adam L., McMahon, Andrew P.
Publicado 2023