Global Changes in Local Protein Dynamics Reduce the Entropic Cost of Carbohydrate Binding in the Arabinose-binding Protein

por MacRaild, Christopher A., Daranas, Antonio Hernández, Bronowska, Agnieszka, Homans, Steve W.
Publicado 2007

Applications of (19)F-NMR in Fragment-Based Drug Discovery

por Norton, Raymond S., Leung, Eleanor W. W., Chandrashekaran, Indu R., MacRaild, Christopher A.
Publicado 2016

Transient antibody-antigen interactions mediate the strain-specific recognition of a conserved malaria epitope

por Krishnarjuna, Bankala, Sugiki, Toshihiko, Morales, Rodrigo A. V., Seow, Jeffrey, Fujiwara, Toshimichi, Wilde, Karyn L., Norton, Raymond S., MacRaild, Christopher A.
Publicado 2018

Insights into the Immunological Properties of Intrinsically Disordered Malaria Proteins Using Proteome Scale Predictions

por Guy, Andrew J., Irani, Vashti, MacRaild, Christopher A., Anders, Robin F., Norton, Raymond S., Beeson, James G., Richards, Jack S., Ramsland, Paul A.
Publicado 2015

Strain-transcending immune response generated by chimeras of the malaria vaccine candidate merozoite surface protein 2

por Krishnarjuna, Bankala, Andrew, Dean, MacRaild, Christopher A., Morales, Rodrigo A. V., Beeson, James G., Anders, Robin F., Richards, Jack S., Norton, Raymond S.
Publicado 2016

Interaction between Plasmodium falciparum Apical Membrane Antigen 1 and the Rhoptry Neck Protein Complex Defines a Key Step in the Erythrocyte Invasion Process of Malaria Parasites

por Richard, Dave, MacRaild, Christopher A., Riglar, David T., Chan, Jo-Anne, Foley, Michael, Baum, Jake, Ralph, Stuart A., Norton, Raymond S., Cowman, Alan F.
Publicado 2010

Molecular Insights into the Interaction between Plasmodium falciparum Apical Membrane Antigen 1 and an Invasion-Inhibitory Peptide

por Wang, Geqing, MacRaild, Christopher A., Mohanty, Biswaranjan, Mobli, Mehdi, Cowieson, Nathan P., Anders, Robin F., Simpson, Jamie S., McGowan, Sheena, Norton, Raymond S., Scanlon, Martin J.
Publicado 2014

Conformational Dynamics and Antigenicity in the Disordered Malaria Antigen Merozoite Surface Protein 2

por MacRaild, Christopher A., Zachrdla, Milan, Andrew, Dean, Krishnarjuna, Bankala, Nováček, Jiří, Žídek, Lukáš, Sklenář, Vladimír, Richards, Jack S., Beeson, James G., Anders, Robin F., Norton, Raymond S.
Publicado 2015

Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate

por Morales, Rodrigo A. V., MacRaild, Christopher A., Seow, Jeffrey, Krishnarjuna, Bankala, Drinkwater, Nyssa, Rouet, Romain, Anders, Robin F., Christ, Daniel, McGowan, Sheena, Norton, Raymond S.
Publicado 2015

Guiding the Immune Response to a Conserved Epitope in MSP2, an Intrinsically Disordered Malaria Vaccine Candidate

por Seow, Jeffrey, Das, Sreedam C., Morales, Rodrigo A. V., Ataide, Ricardo, Krishnarjuna, Bankala, Silk, Mitchell, Chalmers, David K., Richards, Jack, Anders, Robin F., MacRaild, Christopher A., Norton, Raymond S.
Publicado 2021

A new mass spectral library for high-coverage and reproducible analysis of the Plasmodium falciparum–infected red blood cell proteome

por Siddiqui, Ghizal, De Paoli, Amanda, MacRaild, Christopher A, Sexton, Anna E, Boulet, Coralie, Shah, Anup D, Batty, Mitchell B, Schittenhelm, Ralf B, Carvalho, Teresa G, Creek, Darren J
Publicado 2022

Peroxide Antimalarial Drugs Target Redox Homeostasis in Plasmodium falciparum Infected Red Blood Cells

por Siddiqui, Ghizal, Giannangelo, Carlo, De Paoli, Amanda, Schuh, Anna Katharina, Heimsch, Kim C., Anderson, Dovile, Brown, Timothy G., MacRaild, Christopher A., Wu, Jianbo, Wang, Xiaofang, Dong, Yuxiang, Vennerstrom, Jonathan L., Becker, Katja, Creek, Darren J.
Publicado 2022

Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway

por Edgar, Rebecca CS, Siddiqui, Ghizal, Hjerrild, Katheryn, Malcolm, Tess R, Vinh, Natalie B, Webb, Chaille T, Holmes, Clare, MacRaild, Christopher A, Chernih, Hope C, Suen, Willy W, Counihan, Natalie A, Creek, Darren J, Scammells, Peter J, McGowan, Sheena, de Koning-Ward, Tania F
Publicado 2022

Systematic Down-Selection of Repurposed Drug Candidates for COVID-19

por MacRaild, Christopher A., Mohammed, Muzaffar-Ur-Rehman, Faheem, Murugesan, Sankaranarayanan, Styles, Ian K., Peterson, Amanda L., Kirkpatrick, Carl M. J., Cooper, Matthew A., Palombo, Enzo A., Simpson, Moana M., Jain, Hardik A., Agarwal, Vinti, McAuley, Alexander J., Kumar, Anupama, Creek, Darren J., Trevaskis, Natalie L., Vasan, Seshadri S.
Publicado 2022

A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

por Xiong, Xiaochun, Menting, John G., Disotuar, Maria M., Smith, Nicholas A., Delaine, Carlie, Ghabash, Gabrielle, Agrawal, Rahul, Wang, Xiaomin, He, Xiao, Fisher, Simon J., MacRaild, Christopher A., Norton, Raymond S., Gajewiak, Joanna, Forbes, Briony E., Smith, Brian J., Safavi-Hemami, Helena, Olivera, Baldomero, Lawrence, Michael C., Hung-Chieh Chou, Danny
Publicado 2020

Use of Human Lung Tissue Models for Screening of Drugs against SARS-CoV-2 Infection

por McAuley, Alexander J., Jansen van Vuren, Petrus, Mohammed, Muzaffar-Ur-Rehman, Faheem, Goldie, Sarah, Riddell, Shane, Gödde, Nathan J., Styles, Ian K., Bruce, Matthew P., Chahal, Simran, Keating, Stephanie, Blasdell, Kim R., Tachedjian, Mary, O’Brien, Carmel M., Singanallur, Nagendrakumar Balasubramanian, Viana, John Noel, Vashi, Aditya V., Kirkpatrick, Carl M., MacRaild, Christopher A., Shah, Rohan M., Vincan, Elizabeth, Athan, Eugene, Creek, Darren J., Trevaskis, Natalie L., Murugesan, Sankaranarayanan, Kumar, Anupama, Vasan, Seshadri S.
Publicado 2022