Anticancer Activity of Sunitinib Analogues in Human Pancreatic Cancer Cell Cultures under Normoxia and Hypoxia

por Skaraitė, Ieva, Maccioni, Elias, Petrikaitė, Vilma
Publicado 2023

Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase

por Meleddu, Rita, Distinto, Simona, Corona, Angela, Tramontano, Enzo, Bianco, Giulia, Melis, Claudia, Cottiglia, Filippo, Maccioni, Elias
Publicado 2016

5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action

por Corona, Angela, Meleddu, Rita, Delelis, Olivier, Subra, Frederic, Cottiglia, Filippo, Esposito, Francesca, Distinto, Simona, Maccioni, Elias, Tramontano, Enzo
Publicado 2023

Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor

por Corona, Angela, Meleddu, Rita, Esposito, Francesca, Distinto, Simona, Bianco, Giulia, Maccioni, Elias, Le Grice, Stuart SF, Tramontano, Enzo
Publicado 2013

Structure-Based Virtual Screening of Novel Natural Alkaloid Derivatives as Potential Binders of h-telo and c-myc DNA G-Quadruplex Conformations

por Rocca, Roberta, Moraca, Federica, Costa, Giosuè, Alcaro, Stefano, Distinto, Simona, Maccioni, Elias, Ortuso, Francesco, Artese, Anna, Parrotta, Lucia
Publicado 2014

Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase–associated RNase H funct...

por Fois, Benedetta, Corona, Angela, Tramontano, Enzo, Distinto, Simona, Maccioni, Elias, Meleddu, Rita, Caboni, Pierluigi, Floris, Costantino, Cottiglia, Filippo
Publicado 2021

Effects of docosanyl ferulate, a constituent of Withania somnifera, on ethanol- and morphine-elicited conditioned place preference and ERK phosphorylation in the accumbens shell of...

por Maccioni, Riccardo, Serra, Marcello, Marongiu, Jacopo, Cottiglia, Filippo, Maccioni, Elias, Bassareo, Valentina, Morelli, Micaela, Kasture, Sanjay B., Acquas, Elio
Publicado 2022

Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors

por Melis, Claudia, Meleddu, Rita, Angeli, Andrea, Distinto, Simona, Bianco, Giulia, Capasso, Clemente, Cottiglia, Filippo, Angius, Rossella, Supuran, Claudiu T., Maccioni, Elias
Publicado 2016

Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inh...

por Schneider, Anna, Corona, Angela, Spöring, Imke, Jordan, Mareike, Buchholz, Bernd, Maccioni, Elias, Di Santo, Roberto, Bodem, Jochen, Tramontano, Enzo, Wöhrl, Birgitta M.
Publicado 2016

Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B

por Meleddu, Rita, Distinto, Simona, Cirilli, Roberto, Alcaro, Stefano, Yanez, Matilde, Sanna, Maria Luisa, Corona, Angela, Melis, Claudia, Bianco, Giulia, Matyus, Peter, Cottiglia, Filippo, Maccioni, Elias
Publicado 2017

Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6

por Corona, Angela, Meleddu, Rita, Esposito, Francesca, Distinto, Simona, Bianco, Giulia, Masaoka, Takashi, Maccioni, Elias, Menéndez-Arias, Luis, Alcaro, Stefano, Le Grice, Stuart F. J., Tramontano, Enzo
Publicado 2016

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

por Massari, Serena, Corona, Angela, Distinto, Simona, Desantis, Jenny, Caredda, Alessia, Sabatini, Stefano, Manfroni, Giuseppe, Felicetti, Tommaso, Cecchetti, Violetta, Pannecouque, Christophe, Maccioni, Elias, Tramontano, Enzo, Tabarrini, Oriana
Publicado 2018

Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation

por Fois, Benedetta, Distinto, Simona, Meleddu, Rita, Deplano, Serenella, Maccioni, Elias, Floris, Costantino, Rosa, Antonella, Nieddu, Mariella, Caboni, Pierluigi, Sissi, Claudia, Angeli, Andrea, Supuran, Claudiu T., Cottiglia, Filippo
Publicado 2020

Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives

por Meleddu, Rita, Deplano, Serenella, Maccioni, Elias, Ortuso, Francesco, Cottiglia, Filippo, Secci, Daniela, Onali, Alessia, Sanna, Erica, Angeli, Andrea, Angius, Rossella, Alcaro, Stefano, Supuran, Claudiu T., Distinto, Simona
Publicado 2021

Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases

por Distinto, Simona, Meleddu, Rita, Ortuso, Francesco, Cottiglia, Filippo, Deplano, Serenella, Sequeira, Lisa, Melis, Claudia, Fois, Benedetta, Angeli, Andrea, Capasso, Clemente, Angius, Rossella, Alcaro, Stefano, Supuran, Claudiu T., Maccioni, Elias
Publicado 2019

N-Acylbenzenesulfonamide Dihydro-1,3,4-oxadiazole Hybrids: Seeking Selectivity toward Carbonic Anhydrase Isoforms

por Bianco, Giulia, Meleddu, Rita, Distinto, Simona, Cottiglia, Filippo, Gaspari, Marco, Melis, Claudia, Corona, Angela, Angius, Rossella, Angeli, Andrea, Taverna, Domenico, Alcaro, Stefano, Leitans, Janis, Kazaks, Andris, Tars, Kaspars, Supuran, Claudiu T., Maccioni, Elias
Publicado 2017

Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions

por Meleddu, Rita, Corona, Angela, Distinto, Simona, Cottiglia, Filippo, Deplano, Serenella, Sequeira, Lisa, Secci, Daniela, Onali, Alessia, Sanna, Erica, Esposito, Francesca, Cirone, Italo, Ortuso, Francesco, Alcaro, Stefano, Tramontano, Enzo, Mátyus, Péter, Maccioni, Elias
Publicado 2021

Proceedings of the Frontiers of Retrovirology Conference 2016

por Zurnic, Irena, Hütter, Sylvia, Lehmann, Ute, Stanke, Nicole, Reh, Juliane, Kern, Tobias, Lindel, Fabian, Gerresheim, Gesche, Hamann, Martin, Müllers, Erik, Lesbats, Paul, Cherepanov, Peter, Serrao, Erik, Engelman, Alan, Lindemann, Dirk, Da Silva Santos, Claire, Tartour, Kevin, Cimarelli, Andrea, Burdick, Rya, Chen, Jianbo, Sastri, Jaya, Hu, Wei-Shau, Pathak, Vinay, Keppler, Oliver T., Pradeau, Karine, Eiler, Sylvia, Levy, Nicolas, Lennon, Sarah, Cianferani, Sarah, Emiliani, Stéphane, Ruff, Marc, Parissi, Vincent, Rato, Sylvie, Rausell, Antonio, Munoz, Miguel, Telenti, Amalio, Ciuffi, Angela, Zhyvoloup, Alexander, Melamed, Anat, Anderson, Ian, Planas, Delphine, Kriston-Vizi, Janos, Ketteler, Robin, Lee, Chen- Hsuin, Merritt, Andy, Ancuta, Petronela, Bangham, Charles, Fassati, Ariberto, Rodari, Anthony, Van Driessche, Benoit, Galais, Mathilde, Delacourt, Nadége, Fauquenoy, Sylvain, Vanhulle, Caroline, Kula, Anna, Burny, Arsène, Rohr, Olivier, Van Lint, Carine, van Montfort, Thijs, van der Sluis, Renee, Speijer, Dave, Berkhout, Ben, Meng, Bo, Rutkowski, Andrzej, Berry, Neil, Dölken, Lars, Lever, Andrew, Schuster, Thomas, Asbach, Benedikt, Wagner, Ralf, Gross, Christine, Wiesmann, Veit, Kalmer, Martina, Wittenberg, Thomas, Gettemans, Jan, Thoma-Kress, Andrea K., Li, Minghua, Freed, Eric O., Liu, Shan-Lu, Müller, Janis, Münch, Jan, Sewald, Xaver, Uchil, Pradeep, Ladinsky, Mark, Beloor, Jagadish, Pi, Ruoxi, Herrmann, Christin, Motamedi, Nasim, Murooka, Thomas, Brehm, Michael, Greiner, Dale, Mempel, Thorsten, Bjorkman, Pamela, Kumar, Priti, Mothes, Walther, Joas, Simone, Parrish, Erica, Gnanadurai, Clement Wesley, Lump, Edina, Stürzel, Christina M., Parrish, Nicholas F., Sauermann, Ulrike, Töpfer, Katharina, Schultheiss, Tina, Bosinger, Steven, Silvestri, Guido, Apetrei, Cristian, Huot, Nicholas, Müller-Trutwin, Michaela, Sauter, Daniel, Hahn, Beatrice H., Stahl-Hennig, Christiane, Kirchhoff, Frank, Schumann, Gerald, Jung-Klawitter, Sabine, Fuchs, Nina V., Upton, Kyle R., Muñoz-Lopez, Martin, Shukla, Ruchi, Wang, Jichang, Garcia-Canadas, Marta, Lopez-Ruiz, Cesar, Gerhardt, Daniel J., Sebe, Attila, Grabundzija, Ivana, Gerdes, Patricia, Merkert, Sylvia, Pulgarin, Andres, Bock, Anja, Held, Ulrike, Witthuhn, Anett, Haase, Alexandra, Wolvetang, Ernst J., Martin, Ulrich, Ivics, Zoltán, Izsvák, Zsuzsanna, Garcia-Perez, J., Faulkner, Geoffrey J., Hurst, Tara, Katzourakis, Aris, Magiorkinis, Gkikas, Schott, Kerstin, Derua, Rita, Seifried, Janna, Reuter, Andreas, Schmitz, Heike, Tondera, Christiane, Brandariz-Nuñez, Alberto, Diaz-Griffero, Felipe, Janssens, Veerle, König, Renate, Baldauf, Hanna-Mari, Stegmann, Lena, Schwarz, Sarah-Marie, Trotard, Maud, Martin, Margarethe, Lenzi, Gina, Burggraf, Manja, Pan, Xiaoyu, Fregoso, Oliver I., Lim, Efrem S., Abraham, Libin, Erikson, Elina, Nguyen, Laura, Ambiel, Ina, Rutsch, Frank, Kim, Baek, Emerman, Michael, Fackler, Oliver T., Wittmann, Sabine, Behrendt, Rayk, Volkmann, Bianca, Eissmann, Kristin, Gramberg, Thomas, Bolduan, Sebastian, Koppensteiner, Herwig, Regensburg, Stefanie, Brack-Werner, Ruth, Draenert, Rika, Schindler, Michael, Ducroux, Aurélie, Xu, Shuting, Ponnurangam, Aparna, Franz, Sergej, Malassa, Angelina, Ewald, Ellen, Goffinet, Christine, Fung, Sin-Yee, Chan, Ching-Ping, Yuen, Chun-Kit, Kok, Kin-Hang, Chan, Chin-Ping, Jin, Dong-Yan, Dittmer, Ulf, Kmiec, Dorota, Iyer, Shilpa, Stürzel, Christina, Hahn, Beatrice, Ariumi, Yasuo, Yasuda-Inoue, Mariko, Kawano, Koudai, Tateishi, Satoshi, Turelli, Priscilla, Compton, Alex, Roy, Nicolas, Porrot, Françoise, Billet, Anne, Casartelli, Nicoletta, Yount, Jacob, Liang, Chen, Schwartz, Oliver, Magnus, Carsten, Reh, Lucia, Moore, Penny, Uhr, Therese, Weber, Jacqueline, Morris, Lynn, Trkola, Alexandra, Grindberg, Rashel V., Schlaepfer, Erika, Schreiber, Gideon, Simon, Viviana, Speck, Roberto F., Debyser, Zeger, Vranckx, Lenard, Demeulemeester, Jonas, Saleh, Suha, Verdin, Eric, Cereseto, Anna, Christ, Frauke, Gijsbers, Rik, Wang, Gang, Zhao, Na, Das, Atze T., Köstler, Josef, Perdiguero, Beatriz, Esteban, Mariano, Jacobs, Bertram L., Montefiori, David C., LaBranche, Celia C., Yates, Nicole L., Tomaras, Georgia D., Ferrari, Guido, Foulds, Kathryn E., Roederer, Mario, Landucci, Gary, Forthal, Donald N., Seaman, Michael S., Hawkins, Natalie, Self, Steven G., Phogat, Sanjay, Tartaglia, James, Barnett, Susan W., Burke, Brian, Cristillo, Anthony D., Ding, Song, Heeney, Jonathan L., Pantaleo, Giuseppe, Stab, Viktoria, Ensser, Armin, Tippler, Bettina, Burton, Dennis, Tenbusch, Matthias, Überla, Klaus, Alter, Galit, Lofano, Giuseppe, Dugast, Anne-Sophie, Kulkarni, Viraj, Suscovich, Todd, Opazo, Tatiana, Barraza, Felipe, Herrera, Diego, Garces, Andrea, Schwenke, Tomas, Tapia, Diego, Cancino, Jorge, Arriagada, Gloria, Haußner, Christina, Damm, Dominik, Rohrhofer, Anette, Schmidt, Barbara, Eichler, Jutta, Midgley, Rebecca, Wheeldon, James, Piguet, Vincent, Khopkar, Priyanka, Rohamare, Megha, Kulkarni, Smita, Godinho-Santos, Ana, Hance, Allan, Goncalves, Joao, Mammano, Fabrizio, Gasser, Romain, Hamoudi, Meriem, Pellicciotta, Martina, Zhou, Zhicheng, Visdeloup, Clara, Colin, Philippe, Braibant, Martine, Lagane, Bernard, Negroni, Matteo, Wamara, Jula, Bannert, Norbert, Mesplede, Thibault, Osman, Nathan, Anstett, Kaitlin, Liang, Jiaming Calvin, Pham, Hanh Thi, Wainberg, Mark, Shao, Wei, Shan, Jigui, Kearney, Mary, Wu, Xiaolin, Maldarelli, Frank, Mellors, John, Luke, Brian, Coffin, John, Hughes, Stephen, Fricke, Thomas, Opp, Silvana, Shepard, Caitlin, Ivanov, Dmitri, Valle-Casuso, Jose, Kanja, Marine, Cappy, Pierre, Negroni, Matteo, Lener, Daniela, Knyazhanskaya, Ekaterina, Anisenko, Andrey, Zatsepin, Timofey, Gottikh, Marina, Komkov, Alexander, Minervina, Anastasia, Nugmanov, Gaiaz, Nazarov, Vadim, Khodosevich, Konstantin, Mamedov, Ilgar, Lebedev, Yuri, Colomer-Lluch, Marta, Serra-Moreno, Ruth, Sarracino, Ambra, Gharu, Lavina, Pasternak, Alexander, Marcello, Alessandro, McCartin, Ann Marie, Kulkarni, Anurag, Le Douce, Valentin, Gautier, Virginie, Baeyens, Ann, Naessens, Evelien, Van Nuffel, Anouk, Weening, Karin, Reilly, Anne- Marie, Claeys, Eva, Trypsteen, Wim, Vandekerckhove, Linos, Eyckerman, Sven, Gevaert, Kris, Verhasselt, Bruno, Mok, Hoi Ping, Norton, Nicholas, Fun, Axel, Hirst, Jack, Wills, Mark, Miklik, Dalibor, Senigl, Filip, Hejnar, Jiri, Sakuragi, Jun-ichi, Sakuragi, Sayuri, Yokoyama, Masaru, Shioda, Tatsuo, Sato, Hironori, Bodem, Jochen, Moschall, Rebecca, Denk, Sarah, Erkelenz, Steffen, Schenk, Christian, Schaal, Heiner, Donhauser, Norbert, Socher, Ellen, Millen, Sebastian, Sticht, Heinrich, Gross, Christine, Mann, Melanie, Wei, Guochao, Betts, Matthew J., Liu, Yang, Kehl, Timo, Russell, Robert B., Löchelt, Martin, Hohn, Oliver, Mostafa, Saeed, Hanke, Kirsten, Norley, Stephen, Chen, Chia-Yen, Shingai, Masashi, Borrego, Pedro, Taveira, Nuno, Strebel, Klaus, Hellmund, Chris, Meng, Bo, Friedrich, Melanie, Hahn, Friedrich, Setz, Christian, Rauch, Pia, Fraedrich, Kirsten, Matthaei, Alina, Henklein, Petra, Traxdorf, Maximilian, Fossen, Torgils, Schubert, Ulrich, Khwaja, Aya, Galilee, Meytal, Alian, Akram, Schwalbe, Birco, Hauser, Heiko, Schreiber, Michael, Scherpenisse, Mirte, Cho, Young-Keol, Kim, Jungeun, Jeong, Daeun, Trejbalova, Katerina, Benesova, Martina, Kucerova, Dana, Vernerova, Zdenka, Amouroux, Rachel, Hajkova, Petra, Elleder, Daniel, Hron, Tomas, Farkasova, Helena, Padhi, Abinash, Paces, Jan, Zhu, Henan, Gifford, Robert, Murcia, Pablo, Carrozza, Maria Luisa, Niewiadomska, Anna-Maria, Mazzei, Maurizio, Abi-Said, Mounir, Hughes, Joseph, Hué, Stéphane, Gifford, Robert, Obasa, Adetayo, Jacobs, Graeme, Engelbrecht, Susan, Mack, Katharina, Starz, Kathrin, Geyer, Matthias, Bibollet-Ruche, Frederic, Stürzel, Christina, Leoz, Marie, Plantier, Jean Christophe, Argaw-Denboba, Ayele, Balestrieri, Emanuela, Serafino, Annalucia, Bucci, Ilaria, Cipriani, Chiara, Spadafora, Corrado, Sinibaldi-Vallebona, Paolo, Matteucci, Claudia, Jayashree, S. Nandi, Neogi, Ujjwal, Chhangani, Anil K., Rathore, Shravan Sing, Mathur, Bajrang R. J., Abati, Adeyemi, Koç, B. Taylan, Oğuzoğlu, Tuba Çiğdem, Shimauchi, Takatoshi, Caucheteux, Stephan, Turpin, Jocelyn, Finsterbusch, Katja, Tokura, Yoshiki, Souriant, Shanti, Balboa, Luciana, Pingris, Karine, Kviatcowsky, Denise, Raynaud-Messina, Brigitte, Cougoule, Céline, Mercier, Ingrid, Kuroda, Marcelo, González-Montaner, Pablo, Inwentarz, Sandra, Moraña, Eduardo Jose, del Carmen Sasiain, Maria, Neyrolles, Olivier, Maridonneau-Parini, Isabelle, Lugo-Villarino, Geanncarlo, Vérollet, Christel, Herrmann, Alexandra, Thomas, Dominique, Bouzas, Nerea Ferreirós, Lahaye, Xavier, Bhargava, Anvita, Satoh, Takeshi, Gentili, Matteo, Cerboni, Silvia, Silvin, Aymeric, Conrad, Cécile, Ahmed-Belkacem, Hakim, Rodriguez, Elisa C., Guichou, Jean-François, Bosquet, Nathalie, Piel, Matthieu, Le Grand, Roger, King, Megan, Pawlotsky, Jean-Michel, Manel, Nicolas, Hofmann, Henning, Vanwalscappel, Benedicte, Bloch, Nicolin, Landau, Nathaniel, Indik, Stanislav, Hagen, Benedikt, Valle-Casuso, José Carlos, Allouch, Awatef, David, Annie, Barré-Sinoussi, Françoise, Benkirane, Monsef, Pancino, Gianfranco, Saez-Cirion, Asier, Lee, Wing-Yiu, Sloan, Richard, Schulte, Bianca, Opp, Silvana, Blomberg, Jonas, Vargiu, Luana, Rodriguez-Tomé, Patricia, Tramontano, Enzo, Sperber, Göran, Kumari, Namita, Ammosova, Tatiana, Diaz, Sharmeen, Oneal, Patricia, Nekhai, Sergei, Fahrny, Audrey, Gers-Huber, Gustavo, Audigé, Annette, Jayaprakash, Anitha, Sachidanandam, Ravi, Hernandez, Matt, Dillon-White, Marsha, Souriant, Shanti, Pingris, Karine, Raynaud-Messina, Brigitte, Cougoule, Céline, Mercier, Ingrid, Neyrolles, Olivier, Maridonneau-Parini, Isabelle, Lugo-Villarino, Geanncarlo, Maze, Emmanuel, Ham, Claire, Almond, Neil, Towers, Greg, Belshaw, Robert, de Sousa-Pereira, Patrícia, Abrantes, Joana, Pizzato, Massimo, Esteves, Pedro J., Kahle, Tanja, Schmitt, Sven, Merkel, Laura, Reuter, Nina, Stamminger, Thomas, Rosa, Ilaria Dalla, Bishop, Kate, Spinazzola, Antonella, Groom, Harriet, Vieyres, Gabrielle, Müsken, Mathias, Zillinger, Thomas, Hornung, Veit, Barchet, Winfried, Häussler, Susanne, Pietschmann, Thomas, Javed, Aneela, Leuchte, Nicole, Salinas, Gabriela, Opitz, Lennart, Sopper, Sieghart, Mummert, Christiane, Hofmann, Christian, Hückelhoven, Angela G., Bergmann, Silke, Müller-Schmucker, Sandra M., Harrer, Ellen G., Dörrie, Jan, Schaft, Niels, Harrer, Thomas, Cardinaux, Laure, Zahno, M.- L., Vogt, H.- R., Zanoni, R., Bertoni, G., Muenchhoff, Maximilian, Goulder, Philip, Keppler, Oliver, Rebensburg, Stephanie, Helfer, Markus, Zhang, Yuwei, Chen, Huicheng, Bernier, Annie, Gosselin, Annie, Routy, Jean- Pierre, Wöhrl, Birgitta, Schneider, Anna, Corona, Angela, Spöring, Imke, Jordan, Mareike, Buchholz, Bernd, Maccioni, Elias, Di Santo, Roberto, Schweimer, Kristian, Schölz, Christian, Weinert, Brian, Wagner, Sebastian, Beli, Petra, Miyake, Yasuyuki, Qi, Jun, Jensen, Lars, Streicher, Werner, McCarthy, Anna, Westwood, Nicholas, Lain, Sonia, Cox, Jürgen, Matthias, Patrick, Mann, Matthias, Bradner, James, Choudhary, Chunaram, Stern, Marcel, Valletta, Elena, Frezza, Caterina, Marino-Merlo, Francesca, Grelli, Sandro, Serafino, Anna Lucia, Mastino, Antonio, Macchi, Beatrice, Kaulfuß, Meike, Windmann, Sonja, Bayer, Wibke, Mikasi, Sello, Jacobs, Graeme, Heß, Rebecca, Bonsmann, Michael Storcksdieck gen., Kirschning, Carsten, Lepenies, Bernd, Kolenbrander, Anne, Temchura, Vladimir, Iijima, Kenta, Kobayashi, Junya, Ishizaka, Yukihito
Publicado 2016