Still rocking in the structural era: A molecular overview of the small multidrug resistance (SMR) transporter family

por Burata, Olive E., Yeh, Trevor Justin, Macdonald, Christian B., Stockbridge, Randy B.
Publicado 2022

DIMPLE: deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology

por Macdonald, Christian B., Nedrud, David, Grimes, Patrick Rockefeller, Trinidad, Donovan, Fraser, James S., Coyote-Maestas, Willow
Publicado 2023

The structural basis of promiscuity in small multidrug resistance transporters

por Kermani, Ali A., Macdonald, Christian B., Burata, Olive E., Ben Koff, B., Koide, Akiko, Denbaum, Eric, Koide, Shohei, Stockbridge, Randy B.
Publicado 2020

Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain

por Estevam, Gabriella O., Linossi, Edmond M., Macdonald, Christian B., Espinoza, Carla A., Michaud, Jennifer M., Coyote-Maestas, Willow, Collisson, Eric A., Jura, Natalia, Fraser, James S.
Publicado 2023

The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics

por Yee, Sook Wah, Macdonald, Christian, Mitrovic, Darko, Zhou, Xujia, Koleske, Megan L., Yang, Jia, Silva, Dina Buitrago, Grimes, Patrick Rockefeller, Trinidad, Donovan, More, Swati S., Kachuri, Linda, Witte, John S., Delemotte, Lucie, Giacomini, Kathleen M., Coyote-Maestas, Willow
Publicado 2023