Pancreatic cancer-associated stellate cells: A viable target for reducing immunosuppression in the tumor microenvironment

por Mace, Thomas A, Bloomston, Mark, Lesinski, Gregory B
Publicado 2013

Elevation in Body Temperature to Fever Range Enhances and Prolongs Subsequent Responsiveness of Macrophages to Endotoxin Challenge

por Lee, Chen-Ting, Zhong, Lingwen, Mace, Thomas A., Repasky, Elizabeth A.
Publicado 2012

Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains

por Park, Dongju, Shakya, Reena, Koivisto, Christopher, Pitarresi, Jason R., Szabolcs, Matthias, Kladney, Raleigh, Hadjis, Ashley, Mace, Thomas A., Ludwig, Thomas
Publicado 2019

Genetically engineered murine pancreatic cancer models approximate immunophenotypic properties of human patients

por Mace, Thomas A, Pitaressi, Jason, Shakya, Reena, Frankel, Wendy, Eubank, Tim, Bekaii-Saab, Tanios, Bloomston, Mark, Phelps, Mitch, Ludwig, Thomas, Ostrowski, Michael, Lesinski, Gregory B
Publicado 2013

Ultraviolet Light B-Mediated Inhibition of Skin Catalase Activity Promotes Gr-1(+)CD11b(+) Myeloid Cell Expansion

por Sullivan, Nicholas J., Tober, Kathleen L., Burns, Erin M., Schick, Jonathan S., Riggenbach, Judith A., Mace, Thomas A., Bill, Matthew A., Young, Gregory S., Oberyszyn, Tatiana M., Lesinski, Gregory B.
Publicado 2011

A Phase I Study of High-Dose Interleukin-2 With Sorafenib in Patients With Metastatic Renal Cell Carcinoma and Melanoma

por Monk, Paul, Lam, Elaine, Mortazavi, Amir, Kendra, Kari, Lesinski, Gregory B., Mace, Thomas A., Geyer, Susan, Carson, William E., Tahiri, Sanaa, Bhinder, Arvinder, Clinton, Steven K., Olencki, Thomas
Publicado 2014

Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer

por Mace, Thomas A., Shakya, Reena, Elnaggar, Omar, Wilson, Kristin, Komar, Hannah M., Yang, Jennifer, Pitarresi, Jason R., Young, Gregory S., Ostrowski, Michael C., Ludwig, Thomas, Bekaii-Saab, Tanios, Bloomston, Mark, Lesinski, Gregory B.
Publicado 2015

Pancreatic cancer stem cells in patient pancreatic xenografts are sensitive to drozitumab, an agonistic antibody against DR5

por Eng, Jason W.-L., Mace, Thomas A., Sharma, Rohit, Twum, Danielle Y. F., Peng, Peng, Gibbs, John F., Pitoniak, Rosemarie, Reed, Chelsey B., Abrams, Scott I., Repasky, Elizabeth A., Hylander, Bonnie L.
Publicado 2016

Soy isoflavones and their metabolites modulate cytokine-induced natural killer cell function

por Mace, Thomas A., Ware, Michael B., King, Samantha A., Loftus, Shannon, Farren, Matthew R., McMichael, Elizabeth, Scoville, Steven, Geraghty, Connor, Young, Gregory, Carson, William E., Clinton, Steven K., Lesinski, Gregory B.
Publicado 2019

Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo

por Komar, Hannah M., Serpa, Gregory, Kerscher, Claire, Schwoegl, Erin, Mace, Thomas A., Jin, Ming, Yang, Ming-Chen, Chen, Ching-Shih, Bloomston, Mark, Ostrowski, Michael C., Hart, Phil A., Conwell, Darwin L., Lesinski, Gregory B.
Publicado 2017

Structurally Modified Curcumin Analogs Inhibit STAT3 Phosphorylation and Promote Apoptosis of Human Renal Cell Carcinoma and Melanoma Cell Lines

por Bill, Matthew A., Nicholas, Courtney, Mace, Thomas A., Etter, Jonathan P., Li, Chenglong, Schwartz, Eric B., Fuchs, James R., Young, Gregory S., Lin, Li, Lin, Jiayuh, He, Lei, Phelps, Mitch, Li, Pui-Kai, Lesinski, Gregory B.
Publicado 2012

A Pilot Study to Assess Opportunistic Use of CT-Scan for Osteoporosis Screening in Chronic Pancreatitis

por McNabb-Baltar, Julia, Manickavasagan, Hanisha R., Conwell, Darwin L., Lu, Andrew, Yadav, Dhiraj, Hart, Philip A., Lara, Luis F., Cruz-Monserrate, Zobeida, Ing, Steven, Hinton, Alice, Mace, Thomas A., Bradley, David, Shah, Zarine K.
Publicado 2022

Generation of monocyte-derived tumor-associated macrophages using tumor-conditioned media provides a novel method to study tumor-associated macrophages in vitro

por Benner, Brooke, Scarberry, Luke, Suarez-Kelly, Lorena P., Duggan, Megan C., Campbell, Amanda R., Smith, Emily, Lapurga, Gabriella, Jiang, Kallie, Butchar, Jonathan P., Tridandapani, Susheela, Howard, John Harrison, Baiocchi, Robert A., Mace, Thomas A., Carson, William E.
Publicado 2019

Soy-tomato enriched diet reduces inflammation and disease severity in a pre-clinical model of chronic pancreatitis

por Mukherjee, Debasmita, DiVincenzo, Mallory J., Torok, Molly, Choueiry, Fouad, Kumar, Rahul J., Deems, Anna, Miller, Jenna L., Hinton, Alice, Geraghty, Connor, Maranon, Jose Angel, Kulp, Samuel K., Coss, Christopher, Carson, William E., Conwell, Darwin L., Hart, Phil A., Cooperstone, Jessica L., Mace, Thomas A.
Publicado 2020

Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression

por Mukherjee, Debasmita, Chakraborty, Srija, Bercz, Lena, D’Alesio, Liliana, Wedig, Jessica, Torok, Molly A., Pfau, Timothy, Lathrop, Hannah, Jasani, Shrina, Guenther, Abigail, McGue, Jake, Adu-Ampratwum, Daniel, Fuchs, James R., Frankel, Timothy L., Pietrzak, Maciej, Culp, Stacey, Strohecker, Anne M., Skardal, Aleksander, Mace, Thomas A.
Publicado 2023

CD200 promotes immunosuppression in the pancreatic tumor microenvironment

por Choueiry, Fouad, Torok, Molly, Shakya, Reena, Agrawal, Kriti, Deems, Anna, Benner, Brooke, Hinton, Alice, Shaffer, Jami, Blaser, Bradley W, Noonan, Anne M, Williams, Terence M, Dillhoff, Mary, Conwell, Darwin L, Hart, Phil A, Cruz-Monserrate, Zobeida, Bai, Xue-Feng, Carson III, William E, Mace, Thomas A
Publicado 2020

Murine cancer cachexia models replicate elevated catabolic pembrolizumab clearance in humans

por Castillo, Alyssa Marie M., Vu, Trang T., Liva, Sophia G., Chen, Min, Xie, Zhiliang, Thomas, Justin, Remaily, Bryan, Guo, Yizhen, Subrayan, Uma L., Costa, Travis, Helms, Timothy H., Irby, Donald J., Kim, Kyeongmin, Owen, Dwight H., Kulp, Samuel K., Mace, Thomas A., Phelps, Mitch A., Coss, Christopher C.
Publicado 2021

Exploratory analysis of immune checkpoint receptor expression by circulating T cells and tumor specimens in patients receiving neo-adjuvant chemotherapy for operable breast cancer

por Wesolowski, Robert, Stiff, Andrew, Quiroga, Dionisia, McQuinn, Christopher, Li, Zaibo, Nitta, Hiroaki, Savardekar, Himanshu, Benner, Brooke, Ramaswamy, Bhuvaneswari, Lustberg, Maryam, Layman, Rachel M., Macrae, Erin, Kassem, Mahmoud, Williams, Nicole, Sardesai, Sagar, VanDeusen, Jeffrey, Stover, Daniel, Cherian, Mathew, Mace, Thomas A., Yu, Lianbo, Duggan, Megan, Carson, William E.
Publicado 2020

Suppressive myeloid cells are expanded by biliary tract cancer-derived cytokines in vitro and associate with aggressive disease

por Ware, Michael B., Zaidi, Mohammad Y., Yang, Jennifer, Turgeon, Michael K., Krasinskas, Alyssa, Mace, Thomas A., Keenan, Kaitlin, Farren, Matthew R., Ruggieri, Amanda N., Li, Yiman, Zhang, Chao, Chen, Zhengjia, Young, Gregory S., Elnaggar, Omar, Che, Zheng, Maithel, Shishir K., Bekaii-Saab, Tanios, El-Rayes, Bassel, Lesinski, Gregory B.
Publicado 2020

Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell– and CXCR3-dependent manner

por Ware, Michael Brandon, Phillips, Maggie, McQuinn, Christopher, Zaidi, Mohammad Y., Knochelmann, Hannah M., Greene, Emily, Robinson, Brian, Herting, Cameron J., Mace, Thomas A., Chen, Zhengjia, Zhang, Chao, Farren, Matthew R., Ruggieri, Amanda N., Bowers, Jacob S., Shakya, Reena, Farris, Alton B., Young, Gregory, Carson, William E., El-Rayes, Bassel, Paulos, Chrystal M., Lesinski, Gregory B.
Publicado 2023