Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis

por Machado, Diana, Girardini, Miriam, Viveiros, Miguel, Pieroni, Marco
Publicado 2018

Asymmetric inheritance of centrosomes maintains stem cell properties in human neural progenitor cells

por Royall, Lars N, Machado, Diana, Jessberger, Sebastian, Denoth-Lippuner, Annina
Publicado 2023

Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence

por Machado, Diana, Lecorche, Emmanuel, Mougari, Faiza, Cambau, Emmanuelle, Viveiros, Miguel
Publicado 2018

Injection and electroporation of plasmid DNA into human cortical organoids

por Denoth-Lippuner, Annina, Royall, Lars N., Gonzalez-Bohorquez, Daniel, Machado, Diana, Jessberger, Sebastian
Publicado 2022

Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains

por Machado, Diana, Perdigão, João, Portugal, Isabel, Pieroni, Marco, Silva, Pedro A., Couto, Isabel, Viveiros, Miguel
Publicado 2018

Assessment of the BD MGIT TBc Identification Test for the Detection of Mycobacterium tuberculosis Complex in a Network of Mycobacteriology Laboratories

por Machado, Diana, Ramos, Jorge, Couto, Isabel, Cadir, Nureisha, Narciso, Inácio, Coelho, Elizabeth, Viegas, Sofia, Viveiros, Miguel
Publicado 2014

HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality

por Tavares, Ana Maria, Fronteira, Inês, Couto, Isabel, Machado, Diana, Viveiros, Miguel, Abecasis, Ana B., Dias, Sónia
Publicado 2017

Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus

por Costa, Sofia Santos, Falcão, Celeste, Viveiros, Miguel, Machado, Diana, Martins, Marta, Melo-Cristino, José, Amaral, Leonard, Couto, Isabel
Publicado 2011

Contribution of Efflux to the Emergence of Isoniazid and Multidrug Resistance in Mycobacterium tuberculosis

por Machado, Diana, Couto, Isabel, Perdigão, João, Rodrigues, Liliana, Portugal, Isabel, Baptista, Pedro, Veigas, Bruno, Amaral, Leonard, Viveiros, Miguel
Publicado 2012

Correction: Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus

por Costa, Sofia Santos, Falcão, Celeste, Viveiros, Miguel, Machado, Diana, Martins, Marta, Melo-Cristino, José, Amaral, Leonard, Couto, Isabel
Publicado 2013

Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis

por Machado, Diana, Pires, David, Perdigão, João, Couto, Isabel, Portugal, Isabel, Martins, Marta, Amaral, Leonard, Anes, Elsa, Viveiros, Miguel
Publicado 2016

Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli

por Machado, Diana, Fernandes, Laura, Costa, Sofia S., Cannalire, Rolando, Manfroni, Giuseppe, Tabarrini, Oriana, Couto, Isabel, Sabatini, Stefano, Viveiros, Miguel
Publicado 2017

Genetic diversity, transmission dynamics and drug resistance of Mycobacterium tuberculosis in Angola

por Perdigão, João, Clemente, Sofia, Ramos, Jorge, Masakidi, Pedro, Machado, Diana, Silva, Carla, Couto, Isabel, Viveiros, Miguel, Taveira, Nuno, Portugal, Isabel
Publicado 2017

Sodium Hyaluronate Nanocomposite Respirable Microparticles to Tackle Antibiotic Resistance with Potential Application in Treatment of Mycobacterial Pulmonary Infections

por Rossi, Irene, Buttini, Francesca, Sonvico, Fabio, Affaticati, Filippo, Martinelli, Francesco, Annunziato, Giannamaria, Machado, Diana, Viveiros, Miguel, Pieroni, Marco, Bettini, Ruggero
Publicado 2019

Enhancement of antibiotic activity by efflux inhibitors against multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil

por Coelho, Tatiane, Machado, Diana, Couto, Isabel, Maschmann, Raquel, Ramos, Daniela, von Groll, Andrea, Rossetti, Maria L., Silva, Pedro A., Viveiros, Miguel
Publicado 2015

Deciphering the Contribution of Biofilm to the Pathogenesis of Peritoneal Dialysis Infections: Characterization and Microbial Behaviour on Dialysis Fluids

por Sampaio, Joana, Machado, Diana, Gomes, Ana Marta, Machado, Idalina, Santos, Cledir, Lima, Nelson, Carvalho, Maria João, Cabrita, António, Rodrigues, Anabela, Martins, Margarida
Publicado 2016

Bcl-2 Overexpression Improves Survival and Efficacy of Neural Stem Cell-Mediated Enzyme Prodrug Therapy

por Mooney, Rachael, Majid, Asma Abdul, Mota, Daniel, He, Adam, Aramburo, Soraya, Flores, Linda, Covello-Batalla, Jennifer, Machado, Diana, Gonzaga, Joanna, Aboody, Karen S.
Publicado 2018

Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance

por Oppong, Yaa E. A., Phelan, Jody, Perdigão, João, Machado, Diana, Miranda, Anabela, Portugal, Isabel, Viveiros, Miguel, Clark, Taane G., Hibberd, Martin L.
Publicado 2019

Experimental Evidence for Limited in vivo Virulence of Mycobacterium africanum

por Cá, Baltazar, Fonseca, Kaori L., Sousa, Jeremy, Maceiras, Ana Raquel, Machado, Diana, Sanca, Lilica, Rabna, Paulo, Rodrigues, Pedro N. S., Viveiros, Miguel, Saraiva, Margarida
Publicado 2019

Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer

por Mooney, Rachael, Majid, Asma Abdul, Batalla-Covello, Jennifer, Machado, Diana, Liu, Xueli, Gonzaga, Joanna, Tirughana, Revathiswari, Hammad, Mohamed, Lesniak, Maciej S., Curiel, David T., Aboody, Karen S.
Publicado 2018