Case Report: β-thalassemia major on the East African coast

por Macharia, Alexander W., Mochamah, George, Makale, Johnstone, Howard, Thad, Mturi, Neema, Olupot-Olupot, Peter, Färnert, Anna, Ware, Russell E., Williams, Thomas N.
Publicado 2022

An assessment of the impact of host polymorphisms on Plasmodium falciparum vargene expression patterns among Kenyan children

por Warimwe, George M, Fegan, Gregory, Kiragu, Esther W, Musyoki, Jennifer N, Macharia, Alexander W, Marsh, Kevin, Williams, Thomas N, Bull, Peter C
Publicado 2014

The Dantu blood group prevents parasite growth in vivo: Evidence from a controlled human malaria infection study

por Kariuki, Silvia N, Macharia, Alexander W, Makale, Johnstone, Nyamu, Wilfred, Hoffman, Stephen L, Kapulu, Melissa C, Bejon, Philip, Rayner, Julian C, Williams, Thomas N
Publicado 2023

β‐Thalassemia pathogenic variants in a cohort of children from the East African coast

por Macharia, Alexander W., Mochamah, George, Uyoga, Sophie, Ndila, Carolyne M., Nyutu, Gideon, Tendwa, Metrine, Nyatichi, Emily, Makale, Johnstone, Ware, Russell E., Williams, Thomas N.
Publicado 2020

The clinical spectrum of severe childhood malaria in Eastern Uganda

por Olupot-Olupot, Peter, Engoru, Charles, Nteziyaremye, Julius, Chebet, Martin, Ssenyondo, Tonny, Muhindo, Rita, Nyutu, Gideon, Macharia, Alexander W., Uyoga, Sophie, Ndila, Carolyne M., Karamagi, Charles, Maitland, Kathryn, Williams, Thomas N.
Publicado 2020

Haplotype heterogeneity and low linkage disequilibrium reduce reliable prediction of genotypes for the ‑α (3.7I) form of α-thalassaemia using genome-wide microarray data

por Ndila, Carolyne M., Nyirongo, Vysaul, Macharia, Alexander W., Jeffreys, Anna E., Rowlands, Kate, Hubbart, Christina, Busby, George B. J., Band, Gavin, Harding, Rosalind M., Rockett, Kirk A., Williams, Thomas N.
Publicado 2021

Plasma Plasmodium falciparum Histidine-rich Protein 2 Concentrations in Children With Malaria Infections of Differing Severity in Kilifi, Kenya

por Uyoga, Sophie, Wanjiku, Perpetual, Rop, Jesse C, Makale, Johnstone, Macharia, Alexander W, Nyutu, Gideon M, Shebe, Mohammed, Awuondo, Kennedy A, Mturi, Neema, Woodrow, Charles J, Dondorp, Arjen M, Maitland, Kathryn, Williams, Thomas N
Publicado 2020

Sickle cell anaemia and severe Plasmodium falciparum malaria: a secondary analysis of the Transfusion and Treatment of African Children Trial (TRACT)

por Uyoga, Sophie, Olupot-Olupot, Peter, Connon, Roisin, Kiguli, Sarah, Opoka, Robert O, Alaroker, Florence, Muhindo, Rita, Macharia, Alexander W, Dondorp, Arjen M, Gibb, Diana M, Walker, A Sarah, George, Elizabeth C, Maitland, Kathryn, Williams, Thomas N
Publicado 2022

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study

por Ndila, Carolyne M, Uyoga, Sophie, Macharia, Alexander W, Nyutu, Gideon, Peshu, Norbert, Ojal, John, Shebe, Mohammed, Awuondo, Kennedy O, Mturi, Neema, Tsofa, Benjamin, Sepúlveda, Nuno, Clark, Taane G, Band, Gavin, Clarke, Geraldine, Rowlands, Kate, Hubbart, Christina, Jeffreys, Anna, Kariuki, Silvia, Marsh, Kevin, Mackinnon, Margaret, Maitland, Kathryn, Kwiatkowski, Dominic P, Rockett, Kirk A, Williams, Thomas N
Publicado 2018

A predictive algorithm for identifying children with sickle cell anemia among children admitted to hospital with severe anemia in Africa

por Olupot‐Olupot, Peter, Connon, Roisin, Kiguli, Sarah, Opoka, Robert O., Alaroker, Florence, Uyoga, Sophie, Nakuya, Margret, Okiror, William, Nteziyaremye, Julius, Ssenyondo, Tonny, Nabawanuka, Eva, Kayaga, Juliana, Williams Mukisa, Cynthia, Amorut, Denis, Muhindo, Rita, Frost, Gary, Walsh, Kevin, Macharia, Alexander W., Gibb, Diana M., Walker, A. Sarah, George, Elizabeth C., Maitland, Kathryn, Williams, Thomas N.
Publicado 2022

Malaria protection due to sickle haemoglobin depends on parasite genotype

por Band, Gavin, Leffler, Ellen M., Jallow, Muminatou, Sisay-Joof, Fatoumatta, Ndila, Carolyne M., Macharia, Alexander W., Hubbart, Christina, Jeffreys, Anna E., Rowlands, Kate, Nguyen, Thuy, Gonçalves, Sónia, Ariani, Cristina V., Stalker, Jim, Pearson, Richard D., Amato, Roberto, Drury, Eleanor, Sirugo, Giorgio, d’Alessandro, Umberto, Bojang, Kalifa A., Marsh, Kevin, Peshu, Norbert, Saelens, Joseph W., Diakité, Mahamadou, Taylor, Steve M., Conway, David J., Williams, Thomas N., Rockett, Kirk A., Kwiatkowski, Dominic P.
Publicado 2021