PTEN deficiency is associated with reduced sensitivity to mTOR inhibitor in human bladder cancer through the unhampered feedback loop driving PI3K/Akt activation

por Seront, E, Pinto, A, Bouzin, C, Bertrand, L, Machiels, J-P, Feron, O
Publicado 2013

Tumour hypoxia determines the potential of combining mTOR and autophagy inhibitors to treat mammary tumours

por Seront, E, Boidot, R, Bouzin, C, Karroum, O, Jordan, B F, Gallez, B, Machiels, J-P, Feron, O
Publicado 2013

Cancer and renal insufficiency results of the BIRMA study

por Janus, N, Launay-vacher, V, Byloos, E, Machiels, J-P, Duck, L, Kerger, J, Wynendaele, W, Canon, J-L, Lybaert, W, Nortier, J, Deray, G, Wildiers, H
Publicado 2010

Managing cancer patients during the COVID-19 pandemic: an ESMO multidisciplinary expert consensus

por Curigliano, G., Banerjee, S., Cervantes, A., Garassino, M.C., Garrido, P., Girard, N., Haanen, J., Jordan, K., Lordick, F., Machiels, J.P., Michielin, O., Peters, S., Tabernero, J., Douillard, J.Y., Pentheroudakis, G.
Publicado 2020

Salivary gland cancer: ESMO–European Reference Network on Rare Adult Solid Cancers (EURACAN) Clinical Practice Guideline for diagnosis, treatment and follow-up

por van Herpen, C., Vander Poorten, V., Skalova, A., Terhaard, C., Maroldi, R., van Engen, A., Baujat, B., Locati, L.D., Jensen, A.D., Smeele, L., Hardillo, J., Martineau, V. Costes, Trama, A., Kinloch, E., Even, C., Machiels, J.-P.
Publicado 2022

Afatinib versus methotrexate in older patients with second-line recurrent and/or metastatic head and neck squamous cell carcinoma: subgroup analysis of the LUX-Head & Neck 1 trial(...

por Clement, P. M., Gauler, T., Machiels, J. P., Haddad, R. I., Fayette, J., Licitra, L. F., Tahara, M., Cohen, E. E. W., Cupissol, D., Grau, J. J., Guigay, J., Caponigro, F., de Castro, G., de Souza Viana, L., Keilholz, U., del Campo, J. M., Cong, X. J., Ehrnrooth, E., Vermorken, J. B.
Publicado 2016

Biomarkers predict enhanced clinical outcomes with afatinib versus methotrexate in patients with second-line recurrent and/or metastatic head and neck cancer

por Cohen, E. E. W., Licitra, L. F., Burtness, B., Fayette, J., Gauler, T., Clement, P. M., Grau, J. J., del Campo, J. M., Mailliez, A., Haddad, R. I., Vermorken, J. B., Tahara, M., Guigay, J., Geoffrois, L., Merlano, M. C., Dupuis, N., Krämer, N., Cong, X. J., Gibson, N., Solca, F., Ehrnrooth, E., Machiels, J.-P. H.
Publicado 2017

Pan-Asian adaptation of the EHNS–ESMO–ESTRO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with squamous cell carcinoma of the head and neck...

por Keam, B., Machiels, J.-P., Kim, H.R., Licitra, L., Golusinski, W., Gregoire, V., Lee, Y.G., Belka, C., Guo, Y., Rajappa, S.J., Tahara, M., Azrif, M., Ang, M.K., Yang, M.-H., Wang, C.-H., Ng, Q.S., Wan Zamaniah, W.I., Kiyota, N., Babu, S., Yang, K., Curigliano, G., Peters, S., Kim, T.W., Yoshino, T., Pentheroudakis, G.
Publicado 2021

Safety of systemic anti-cancer treatment in oncology patients with non-severe COVID-19: a cohort study

por van Marcke, C., Honoré, N., van der Elst, A., Beyaert, S., Derouane, F., Dumont, C., Aboubakar Nana, F., Baurain, J. F., Borbath, I., Collard, P., Cornélis, F., De Cuyper, A., Duhoux, F. P., Filleul, B., Galot, R., Gizzi, M., Mazzeo, F., Pieters, T., Seront, E., Sinapi, I., Van den Eynde, M., Whenham, N., Yombi, J. C., Scohy, A., van Maanen, A., Machiels, J. P.
Publicado 2021

Isatuximab plus atezolizumab in patients with advanced solid tumors: results from a phase I/II, open-label, multicenter study

por Simonelli, M., Garralda, E., Eskens, F., Gil-Martin, M., Yen, C.-J., Obermannova, R., Chao, Y., Lonardi, S., Melichar, B., Moreno, V., Yu, M.-L., Bongiovanni, A., Calvo, E., Rottey, S., Machiels, J.-P., Gonzalez-Martin, A., Paz-Ares, L., Chang, C.-L., Mason, W., Lin, C.-C., Reardon, D.A., Vieito, M., Santoro, A., Meng, R., Abbadessa, G., Menas, F., Lee, H., Liu, Q., Combeau, C., Ternes, N., Ziti-Ljajic, S., Massard, C.
Publicado 2022