Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site

por Carra, John H, McHugh, Colleen A, Mulligan, Sheila, Machiesky, LeeAnn M, Soares, Alexei S, Millard, Charles B
Publicado 2007

Characterization of IgG1 Fc Deamidation at Asparagine 325 and Its Impact on Antibody-dependent Cell-mediated Cytotoxicity and FcγRIIIa Binding

por Lu, Xiaojun, Machiesky, Lee Ann, De Mel, Niluka, Du, Qun, Xu, Weichen, Washabaugh, Michael, Jiang, Xu-Rong, Wang, Jihong
Publicado 2020

Fc-mediated functions of nirsevimab complement direct respiratory syncytial virus neutralization but are not required for optimal prophylactic protection

por Brady, Tyler, Cayatte, Corinne, Roe, Tiffany L., Speer, Scott D., Ji, Hong, Machiesky, LeeAnn, Zhang, Tianhui, Wilkins, Deidre, Tuffy, Kevin M., Kelly, Elizabeth J.
Publicado 2023

Activity of murine surrogate antibodies for durvalumab and tremelimumab lacking effector function and the ability to deplete regulatory T cells in mouse models of cancer

por Schofield, Darren J., Percival-Alwyn, Jennifer, Rytelewski, Mateusz, Hood, John, Rothstein, Raymond, Wetzel, Leslie, McGlinchey, Kelly, Adjei, Grace, Watkins, Amanda, Machiesky, LeeAnn, Chen, Weimin, Andrews, John, Groves, Maria, Morrow, Michelle, Stewart, Ross A., Leinster, Andrew, Wilkinson, Robert W., Hammond, Scott A., Luheshi, Nadia, Dobson, Claire, Oberst, Michael
Publicado 2021

ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome

por Baker, Alexander T., Boyd, Ryan J., Sarkar, Daipayan, Teijeira-Crespo, Alicia, Chan, Chun Kit, Bates, Emily, Waraich, Kasim, Vant, John, Wilson, Eric, Truong, Chloe D., Lipka-Lloyd, Magdalena, Fromme, Petra, Vermaas, Josh, Williams, Dewight, Machiesky, LeeAnn, Heurich, Meike, Nagalo, Bolni M., Coughlan, Lynda, Umlauf, Scott, Chiu, Po-Lin, Rizkallah, Pierre J., Cohen, Taylor S., Parker, Alan L., Singharoy, Abhishek, Borad, Mitesh J.
Publicado 2021

Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies

por Dippel, Andrew, Gallegos, Austin, Aleti, Vineela, Barnes, Arnita, Chen, Xiaoru, Christian, Elizabeth, Delmar, Jared, Du, Qun, Esfandiary, Reza, Farmer, Erika, Garcia, Andrew, Li, Qing, Lin, Jia, Liu, Weiyi, Machiesky, LeeAnn, Mody, Neil, Parupudi, Arun, Prophet, Meagan, Rickert, Keith, Rosenthal, Kim, Ren, Song, Shandilya, Harini, Varkey, Reena, Wons, Kevin, Wu, Yuling, Loo, Yueh-Ming, Esser, Mark T., Kallewaard, Nicole L., Rajan, Sarav, Damschroder, Melissa, Xu, Weichen, Kaplan, Gilad
Publicado 2022