Substrate reduction therapy for inborn errors of metabolism

por Yue, Wyatt W., Mackinnon, Sabrina, Bezerra, Gustavo A.
Publicado 2019

Novel Starting Points for Human Glycolate Oxidase Inhibitors, Revealed by Crystallography-Based Fragment Screening

por Mackinnon, Sabrina R., Bezerra, Gustavo A., Krojer, Tobias, Szommer, Tamas, von Delft, Frank, Brennan, Paul E., Yue, Wyatt W.
Publicado 2022

Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia

por Mackinnon, Sabrina R., Krojer, Tobias, Foster, William R., Diaz-Saez, Laura, Tang, Manshu, Huber, Kilian V. M., von Delft, Frank, Lai, Kent, Brennan, Paul E., Arruda Bezerra, Gustavo, Yue, Wyatt W.
Publicado 2021

Arginine does not rescue p.Q188R mutation deleterious effect in classic galactosemia

por Haskovic, Minela, Derks, Britt, van der Ploeg, Liesbeth, Trommelen, Jorn, Nyakayiru, Jean, van Loon, Luc J. C., Mackinnon, Sabrina, Yue, Wyatt W., Peake, Roy W. A., Zha, Li, Demirbas, Didem, Qi, Wanshu, Huang, Xiaoping, Berry, Gerard T., Achten, Jelle, Bierau, Jörgen, Rubio-Gozalbo, M. Estela, Coelho, Ana I.
Publicado 2018