Antibody Fc engineering for enhanced neonatal Fc receptor binding and prolonged circulation half-life

por Mackness, Brian C., Jaworski, Julie A., Boudanova, Ekaterina, Park, Anna, Valente, Delphine, Mauriac, Christine, Pasquier, Olivier, Schmidt, Thorsten, Kabiri, Mostafa, Kandira, Abdullah, Radošević, Katarina, Qiu, Huawei
Publicado 2019

Pharmacokinetics of novel Fc-engineered monoclonal and multispecific antibodies in cynomolgus monkeys and humanized FcRn transgenic mouse models

por Valente, Delphine, Mauriac, Christine, Schmidt, Thorsten, Focken, Ingo, Beninga, Jochen, Mackness, Brian, Qiu, Huawei, Vicat, Pascale, Kandira, Abdullah, Radošević, Katarina, Rao, Srini, Darbyshire, John, Kabiri, Mostafa
Publicado 2020

A platform-agnostic, function first-based antibody discovery strategy using plasmid-free mammalian expression of antibodies

por Zhang, Ruijun, Prabakaran, Ponraj, Yu, Xiaocong, Mackness, Brian C., Boudanova, Ekaterina, Hopke, Joern, Sancho, Jose, Saleh, Jacqueline, Cho, HyunSuk, Zhang, Ningning, Simonds-Mannes, Helene, Stimple, Samuel D., Hoffmann, Dietmar, Park, Anna, Chowdhury, Partha S., Rao, Sambasiva P.
Publicado 2021

Honing-in antigen-specific cells during antibody discovery: a user-friendly process to mine a deeper repertoire

por Mahendra, Ankit, Haque, Aftabul, Prabakaran, Ponraj, Mackness, Brian C., Fuller, Thomas P., Liu, Xiaohua, Kathuria, Sagar V., Wang, Yui-Hsi, Amatya, Nilesh, Yu, Xiaocong, Hopke, Joern, Hoffmann, Dietmar, Bric-Furlong, Eva, Zhang, Ningning, Cho, Hyun-Suk, Zhang, Ruijun, Sancho, Jose, Saleh, Jacqueline, Rao, Sambasiva P., Wendt, Maria, Chowdhury, Partha S.
Publicado 2022