Galantamine improves olfactory learning in the Ts65Dn mouse model of Down syndrome

por Simoes de Souza, Fabio M., Busquet, Nicolas, Blatner, Megan, Maclean, Kenneth N., Restrepo, Diego
Publicado 2011

Effects of Neonatal Neural Progenitor Cell Implantation on Adult Neuroanatomy and Cognition in the Ts65Dn Model of Down Syndrome

por Rachubinski, Angela L., Crowley, Shannon K., Sladek, John R., Maclean, Kenneth N., Bjugstad, Kimberly B.
Publicado 2012

A de novo 2.78-Mb duplication on chromosome 21q22.11 implicates candidate genes in the partial trisomy 21 phenotype

por Weisfeld-Adams, James D, Tkachuk, Amanda K, Maclean, Kenneth N, Meeks, Naomi L, Scott, Stuart A
Publicado 2016

A de novo 2.78-Mb duplication on chromosome 21q22.11 implicates candidate genes in the partial trisomy 21 phenotype

por Weisfeld-Adams, James D, Tkachuk, Amanda K, Maclean, Kenneth N, Meeks, Naomi L, Scott, Stuart A
Publicado 2017

Methylene-tetrahydrofolate reductase contributes to allergic airway disease

por Eyring, Kenneth R., Pedersen, Brent S., Maclean, Kenneth N., Stabler, Sally P., Yang, Ivana V., Schwartz, David A.
Publicado 2018

Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap

por Jiang, Hua, Hurt, K. Joseph, Breen, Kelsey, Stabler, Sally P., Allen, Robert H., Orlicky, David J., Maclean, Kenneth N.
Publicado 2015

The burden of trisomy 21 disrupts the proteostasis network in Down syndrome

por Aivazidis, Stefanos, Coughlan, Christina M., Rauniyar, Abhishek K., Jiang, Hua, Liggett, L. Alexander, Maclean, Kenneth N., Roede, James R.
Publicado 2017

Loss of TDAG51 Results in Mature-Onset Obesity, Hepatic Steatosis, and Insulin Resistance by Regulating Lipogenesis

por Basseri, Sana, Lhoták, Šárka, Fullerton, Morgan D., Palanivel, Rengasamy, Jiang, Hua, Lynn, Edward G., Ford, Rebecca J., Maclean, Kenneth N., Steinberg, Gregory R., Austin, Richard C.
Publicado 2013

Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment

por Maclean, Kenneth N., Sikora, Jakub, Kožich, Viktor, Jiang, Hua, Greiner, Lori S., Kraus, Eva, Krijt, Jakub, Crnic, Linda S., Allen, Robert H., Stabler, Sally P., Elleder, Milan, Kraus, Jan P.
Publicado 2010

SNARE proteins rescue impaired autophagic flux in Down syndrome

por Aivazidis, Stefanos, Jain, Abhilasha, Rauniyar, Abhishek K., Anderson, Colin C., Marentette, John O., Orlicky, David J., Fritz, Kristofer S., Harris, Peter S., Siegel, David, Maclean, Kenneth N., Roede, James R.
Publicado 2019

Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage

por Shearn, Colin T., Orlicky, David J., McCullough, Rebecca L., Jiang, Hua, Maclean, Kenneth N., Mercer, Kelly E., Stiles, Bangyan L., Saba, Laura M., Ronis, Martin J., Petersen, Dennis R.
Publicado 2016

GDF10 blocks hepatic PPARγ activation to protect against diet-induced liver injury

por Platko, Khrystyna, Lebeau, Paul F., Byun, Jae Hyun, Poon, Samantha V., Day, Emily A., MacDonald, Melissa E., Holzapfel, Nicholas, Mejia-Benitez, Aurora, Maclean, Kenneth N., Krepinsky, Joan C., Austin, Richard C.
Publicado 2019

Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice

por Lebeau, Paul F., Byun, Jae Hyun, Platko, Khrystyna, Al-Hashimi, Ali A., Lhoták, Šárka, MacDonald, Melissa E., Mejia-Benitez, Aurora, Prat, Annik, Igdoura, Suleiman A., Trigatti, Bernardo, Maclean, Kenneth N., Seidah, Nabil G., Austin, Richard C.
Publicado 2019

A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine...

por Maclean, Kenneth N., Sikora, Jakub, Kožich, Viktor, Jiang, Hua, Greiner, Lori S., Kraus, Eva, Krijt, Jakub, Overdier, Katherine H., Collard, Renata, Brodsky, Gary L., Meltesen, Lynne, Crnic, Linda S., Allen, Robert H., Stabler, Sally P., Elleder, Milan, Rozen, Rima, Patterson, David, Kraus, Jan P.
Publicado 2010

Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates

por Wesolowski, Stephanie R., Mulligan, Christopher M., Janssen, Rachel C., Baker, Peter R., Bergman, Bryan C., D'Alessandro, Angelo, Nemkov, Travis, Maclean, Kenneth N., Jiang, Hua, Dean, Tyler A., Takahashi, Diana L., Kievit, Paul, McCurdy, Carrie E., Aagaard, Kjersti M., Friedman, Jacob E.
Publicado 2018

Deficiency of TDAG51 Protects Against Atherosclerosis by Modulating Apoptosis, Cholesterol Efflux, and Peroxiredoxin‐1 Expression

por Hossain, Gazi S., Lynn, Edward G., Maclean, Kenneth N., Zhou, Ji, Dickhout, Jeffrey G., Lhoták, Šárka, Trigatti, Bernardo, Capone, John, Rho, Jaerang, Tang, Damu, McCulloch, Christopher A., Al‐Bondokji, Imtisal, Malloy, Mary J., Pullinger, Clive R., Kane, John P., Li, Yonghong, Shiffman, Dov, Austin, Richard C.
Publicado 2013