The right tools for the job: the central role for next generation chemical probes and chemistry-based target deconvolution methods in phenotypic drug discovery

por Jörg, Manuela, Madden, Katrina S.
Publicado 2021

Mycobacterium tuberculosis infection triggers epigenetic changes that are enriched in a type I IFN signature

por Madden, Katrina, El Hamra, Rayan, Berton, Stefania, Felker, Jake, Alvarez, Gonzalo G, Blais, Alexandre, Sun, Jim
Publicado 2023

Mechanistic Investigation of the Androgen Receptor DNA-Binding Domain and Modulation via Direct Interactions with DNA Abasic Sites: Understanding the Mechanisms Involved in Castrat...

por Xu, Shangze, Kondal, Matthew D., Ahmad, Ayaz, Zhu, Ruidi, Fan, Lanyu, Zaborniak, Piotr, Madden, Katrina S., de Souza, João V., Bronowska, Agnieszka K.
Publicado 2023

Pilot Study to Quantify Palladium Impurities in Lead-like Compounds Following Commonly Used Purification Techniques

por Chatzopoulou, Maria, Madden, Katrina S., Bromhead, Liam J., Greaves, Christopher, Cogswell, Thomas J., Da Silva Pinto, Solange, Galan, Sébastien R. G., Georgiou, Irene, Kennedy, Matthew S., Kennett, Alice, Apps, Geraint, Russell, Angela J., Wynne, Graham M.
Publicado 2022

A tubulin binding molecule drives differentiation of acute myeloid leukemia cells

por Jackson, Thomas R., Vuorinen, Aini, Josa-Culleré, Laia, Madden, Katrina S., Conole, Daniel, Cogswell, Thomas J., Wilkinson, Isabel V.L., Kettyle, Laura M., Zhang, Douzi, O’Mahony, Alison, Gracias, Deanne, McCall, Lorna, Westwood, Robert, Terstappen, Georg C., Davies, Stephen G., Tate, Edward W., Wynne, Graham M., Vyas, Paresh, Russell, Angela J., Milne, Thomas A.
Publicado 2022