Insulin Resistance Induced by Hyperinsulinemia Coincides with a Persistent Alteration at the Insulin Receptor Tyrosine Kinase Domain

por Catalano, Karyn J., Maddux, Betty A., Szary, Jaroslaw, Youngren, Jack F., Goldfine, Ira D., Schaufele, Fred
Publicado 2014

Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity

por Masharani, Umesh, Gjerde, Christine, McCoy, Shelley, Maddux, Betty A, Hessler, Danielle, Goldfine, Ira D, Youngren, Jack F
Publicado 2012

Insulin Resistance in Non-Obese Subjects Is Associated with Activation of the JNK Pathway and Impaired Insulin Signaling in Skeletal Muscle

por Masharani, Umesh B., Maddux, Betty A., Li, Xiaojuan, Sakkas, Giorgos K., Mulligan, Kathleen, Schambelan, Morris, Goldfine, Ira D., Youngren, Jack F.
Publicado 2011

A Fully Human, Allosteric Monoclonal Antibody That Activates the Insulin Receptor and Improves Glycemic Control

por Bhaskar, Vinay, Goldfine, Ira D., Bedinger, Daniel H., Lau, Angela, Kuan, Hua F., Gross, Lisa M., Handa, Masahisa, Maddux, Betty A., Watson, Susan R., Zhu, Shirley, Narasimha, Ajay J., Levy, Raphael, Webster, Lynn, Wijesuriya, Sujeewa D., Liu, Naichi, Wu, Xiaorong, Chemla-Vogel, David, Tran, Catarina, Lee, Steve R., Wong, Steve, Wilcock, Diane, White, Mark L., Corbin, John A.
Publicado 2012

Improved Glucose Metabolism In Vitro and In Vivo by an Allosteric Monoclonal Antibody That Increases Insulin Receptor Binding Affinity

por Corbin, John A., Bhaskar, Vinay, Goldfine, Ira D., Bedinger, Daniel H., Lau, Angela, Michelson, Kristen, Gross, Lisa M., Maddux, Betty A., Kuan, Hua F., Tran, Catarina, Lao, Llewelyn, Handa, Masahisa, Watson, Susan R., Narasimha, Ajay J., Zhu, Shirley, Levy, Raphael, Webster, Lynn, Wijesuriya, Sujeewa D., Liu, Naichi, Wu, Xiaorong, Chemla-Vogel, David, Lee, Steve R., Wong, Steve, Wilcock, Diane, White, Mark L.
Publicado 2014

Inhibition of insulin receptor function by a human, allosteric monoclonal antibody: A potential new approach for the treatment of hyperinsulinemic hypoglycemia

por Corbin, John A, Bhaskar, Vinay, Goldfine, Ira D, Issafras, Hassan, Bedinger, Daniel H, Lau, Angela, Michelson, Kristen, Gross, Lisa M, Maddux, Betty A, Kuan, Hua F, Tran, Catarina, Lao, Llewelyn, Handa, Masahisa, Watson, Susan R, Narasimha, Ajay J, Zhu, Shirley, Levy, Raphael, Webster, Lynn, Wijesuriya, Sujeewa D, Liu, Naichi, Wu, Xiaorong, Chemla-Vogel, David, Lee, Steve R, Wong, Steve, Wilcock, Diane, Rubin, Paul, White, Mark L
Publicado 2014