Targeting the Autophagy/Lysosomal Degradation Pathway in Parkinson´s Disease

por Rivero-Ríos, Pilar, Madero-Pérez, Jesús, Fernández, Belén, Hilfiker, Sabine
Publicado 2016

RAB7L1-Mediated Relocalization of LRRK2 to the Golgi Complex Causes Centrosomal Deficits via RAB8A

por Madero-Pérez, Jesús, Fernández, Belén, Lara Ordóñez, Antonio Jesús, Fdez, Elena, Lobbestael, Evy, Baekelandt, Veerle, Hilfiker, Sabine
Publicado 2018

The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A

por Rivero-Ríos, Pilar, Romo-Lozano, María, Madero-Pérez, Jesús, Thomas, Andrew P., Biosa, Alice, Greggio, Elisa, Hilfiker, Sabine
Publicado 2019

GTP binding regulates cellular localization of Parkinson's disease-associated LRRK2

por Blanca Ramírez, Marian, Ordóñez, Antonio Jesús Lara, Fdez, Elena, Madero-Pérez, Jesús, Gonnelli, Adriano, Drouyer, Matthieu, Chartier-Harlin, Marie-Christine, Taymans, Jean-Marc, Bubacco, Luigi, Greggio, Elisa, Hilfiker, Sabine
Publicado 2017

Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement

por Fdez, Elena, Madero-Pérez, Jesús, Lara Ordóñez, Antonio J., Naaldijk, Yahaira, Fasiczka, Rachel, Aiastui, Ana, Ruiz-Martínez, Javier, López de Munain, Adolfo, Cowley, Sally A., Wade-Martins, Richard, Hilfiker, Sabine
Publicado 2022

RAB8, RAB10 and RILPL1 contribute to both LRRK2 kinase–mediated centrosomal cohesion and ciliogenesis deficits

por Lara Ordónez, Antonio Jesús, Fernández, Belén, Fdez, Elena, Romo-Lozano, María, Madero-Pérez, Jesús, Lobbestael, Evy, Baekelandt, Veerle, Aiastui, Ana, López de Munaín, Adolfo, Melrose, Heather L, Civiero, Laura, Hilfiker, Sabine
Publicado 2019

Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation

por Madero-Pérez, Jesús, Fdez, Elena, Fernández, Belén, Lara Ordóñez, Antonio J., Blanca Ramírez, Marian, Gómez-Suaga, Patricia, Waschbüsch, Dieter, Lobbestael, Evy, Baekelandt, Veerle, Nairn, Angus C., Ruiz-Martínez, Javier, Aiastui, Ana, López de Munain, Adolfo, Lis, Pawel, Comptdaer, Thomas, Taymans, Jean-Marc, Chartier-Harlin, Marie-Christine, Beilina, Alexandria, Gonnelli, Adriano, Cookson, Mark R., Greggio, Elisa, Hilfiker, Sabine
Publicado 2018

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

por Tracy, Tara E., Madero-Pérez, Jesus, Swaney, Danielle L., Chang, Timothy S., Moritz, Michelle, Konrad, Csaba, Ward, Michael E., Stevenson, Erica, Hüttenhain, Ruth, Kauwe, Grant, Mercedes, Maria, Sweetland-Martin, Lauren, Chen, Xu, Mok, Sue-Ann, Wong, Man Ying, Telpoukhovskaia, Maria, Min, Sang-Won, Wang, Chao, Dongmin Sohn, Peter, Martin, Jordie, Zhou, Yungui, Luo, Wenjie, Trojanowski, John Q., Lee, Virginia M.Y., Gong, Shiaoching, Manfredi, Giovanni, Coppola, Giovanni, Krogan, Nevan J., Geschwind, Daniel H., Gan, Li
Publicado 2022