Tilorone, a Broad-Spectrum Antiviral for Emerging Viruses

por Ekins, Sean, Madrid, Peter B.
Publicado 2020

Tilorone: a Broad-Spectrum Antiviral Invented in the USA and Commercialized in Russia and beyond

por Ekins, Sean, Lane, Thomas R., Madrid, Peter B.
Publicado 2020

Correction to: Tilorone: a Broad-Spectrum Antiviral Invented in the USA and Commercialized in Russia and beyond

por Ekins, Sean, Lane, Thomas R., Madrid, Peter B.
Publicado 2020

SynRoute: A Retrosynthetic Planning Software

por Latendresse, Mario, Malerich, Jeremiah P., Herson, James, Krummenacker, Markus, Szeto, Judy, Vu, Vi-Anh, Collins, Nathan, Madrid, Peter B.
Publicado 2023

Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection

por Lane, Thomas R., Massey, Christopher, Comer, Jason E., Anantpadma, Manu, Freundlich, Joel S., Davey, Robert A., Madrid, Peter B., Ekins, Sean
Publicado 2019

Bulged DNA substrates for identifying poxvirus resolvase inhibitors

por Culyba, Matthew, Hwang, Young, Attar, Sana, Madrid, Peter B., Bupp, James, Huryn, Donna, Sanchez, Luis, Grobler, Jay, Miller, Michael D., Bushman, Frederic D.
Publicado 2012

Ebola Virus Bayesian Machine Learning Models Enable New in Vitro Leads

por Anantpadma, Manu, Lane, Thomas, Zorn, Kimberley M., Lingerfelt, Mary A., Clark, Alex M., Freundlich, Joel S., Davey, Robert A., Madrid, Peter B., Ekins, Sean
Publicado 2019

Repurposing Pyramax®, quinacrine and tilorone as treatments for Ebola virus disease

por Lane, Thomas R., Dyall, Julie, Mercer, Luke, Goodin, Caleb, Foil, Daniel H., Zhou, Huanying, Postnikova, Elena, Liang, Janie Y., Holbrook, Michael R., Madrid, Peter B., Ekins, Sean
Publicado 2020

Mega-High-Throughput Screening Platform for the Discovery of Biologically Relevant Sequence-Defined Non-Natural Polymers

por Avital-Shmilovici, Michal, Liu, Xiaohe, Shaler, Thomas, Lowenthal, Andrew, Bourbon, Pauline, Snider, Janey, Tambo-Ong, Arlyn, Repellin, Claire, Yniguez, Kenya, Sambucetti, Lidia, Madrid, Peter B., Collins, Nathan
Publicado 2022

Combining Metabolite-Based Pharmacophores with Bayesian Machine Learning Models for Mycobacterium tuberculosis Drug Discovery

por Ekins, Sean, Madrid, Peter B., Sarker, Malabika, Li, Shao-Gang, Mittal, Nisha, Kumar, Pradeep, Wang, Xin, Stratton, Thomas P., Zimmerman, Matthew, Talcott, Carolyn, Bourbon, Pauline, Travers, Mike, Yadav, Maneesh, Freundlich, Joel S.
Publicado 2015

Predictive modeling targets thymidylate synthase ThyX in Mycobacterium tuberculosis

por Djaout, Kamel, Singh, Vinayak, Boum, Yap, Katawera, Victoria, Becker, Hubert F., Bush, Natassja G., Hearnshaw, Stephen J., Pritchard, Jennifer E., Bourbon, Pauline, Madrid, Peter B., Maxwell, Anthony, Mizrahi, Valerie, Myllykallio, Hannu, Ekins, Sean
Publicado 2016

A Systematic Screen of FDA-Approved Drugs for Inhibitors of Biological Threat Agents

por Madrid, Peter B., Chopra, Sidharth, Manger, Ian D., Gilfillan, Lynne, Keepers, Tiffany R., Shurtleff, Amy C., Green, Carol E., Iyer, Lalitha V., Dilks, Holli Hutcheson, Davey, Robert A., Kolokoltsov, Andrey A., Carrion, Ricardo, Patterson, Jean L., Bavari, Sina, Panchal, Rekha G., Warren, Travis K., Wells, Jay B., Moos, Walter H., Burke, RaeLyn L., Tanga, Mary J.
Publicado 2013

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms

por Puhl, Ana C., Fritch, Ethan J., Lane, Thomas R., Tse, Longping V., Yount, Boyd L., Sacramento, Carolina Q., Fintelman-Rodrigues, Natalia, Tavella, Tatyana Almeida, Maranhão Costa, Fabio Trindade, Weston, Stuart, Logue, James, Frieman, Matthew, Premkumar, Lakshmanane, Pearce, Kenneth H., Hurst, Brett L., Andrade, Carolina Horta, Levi, James A., Johnson, Nicole J., Kisthardt, Samantha C., Scholle, Frank, Souza, Thiago Moreno L., Moorman, Nathaniel John, Baric, Ralph S., Madrid, Peter B., Ekins, Sean
Publicado 2021