A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B

por De Antoni, Anna, Maffini, Stefano, Knapp, Stefan, Musacchio, Andrea, Santaguida, Stefano
Publicado 2012

Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint

por O'Connor, Aisling, Maffini, Stefano, Rainey, Michael D., Kaczmarczyk, Agnieszka, Gaboriau, David, Musacchio, Andrea, Santocanale, Corrado
Publicado 2015

Basis of catalytic assembly of the mitotic checkpoint complex

por Faesen, Alex C., Thanasoula, Maria, Maffini, Stefano, Breit, Claudia, Müller, Franziska, van Gerwen, Suzan, Bange, Tanja, Musacchio, Andrea
Publicado 2017

The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases

por Ciossani, Giuseppe, Overlack, Katharina, Petrovic, Arsen, Huis in 't Veld, Pim J., Koerner, Carolin, Wohlgemuth, Sabine, Maffini, Stefano, Musacchio, Andrea
Publicado 2018

A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint

por Overlack, Katharina, Primorac, Ivana, Vleugel, Mathijs, Krenn, Veronica, Maffini, Stefano, Hoffmann, Ingrid, Kops, Geert J P L, Musacchio, Andrea
Publicado 2015

Cellular response upon proliferation in the presence of an active mitotic checkpoint

por Corno, Andrea, Chiroli, Elena, Gross, Fridolin, Vernieri, Claudio, Matafora, Vittoria, Maffini, Stefano, Cosentino Lagomarsino, Marco, Bachi, Angela, Ciliberto, Andrea
Publicado 2019

BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis

por Singh, Priyanka, Pesenti, Marion E., Maffini, Stefano, Carmignani, Sara, Hedtfeld, Marius, Petrovic, Arsen, Srinivasamani, Anupallavi, Bange, Tanja, Musacchio, Andrea
Publicado 2021

BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling

por Overlack, Katharina, Bange, Tanja, Weissmann, Florian, Faesen, Alex C., Maffini, Stefano, Primorac, Ivana, Müller, Franziska, Peters, Jan-Michael, Musacchio, Andrea
Publicado 2017

Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors

por Goebel, Lisa, Kirschner, Tonia, Koska, Sandra, Rai, Amrita, Janning, Petra, Maffini, Stefano, Vatheuer, Helge, Czodrowski, Paul, Goody, Roger S, Müller, Matthias P, Rauh, Daniel
Publicado 2023

Spatiotemporal control of mitosis by the conserved spindle matrix protein Megator

por Lince-Faria, Mariana, Maffini, Stefano, Orr, Bernard, Ding, Yun, Cláudia Florindo, Sunkel, Claudio E., Tavares, Álvaro, Johansen, Jørgen, Johansen, Kristen M., Maiato, Helder
Publicado 2009

Decoding the centromeric nucleosome through CENP-N

por Pentakota, Satyakrishna, Zhou, Keda, Smith, Charlotte, Maffini, Stefano, Petrovic, Arsen, Morgan, Garry P, Weir, John R, Vetter, Ingrid R, Musacchio, Andrea, Luger, Karolin
Publicado 2017

Structure of the RZZ complex and molecular basis of Spindly‐driven corona assembly at human kinetochores

por Raisch, Tobias, Ciossani, Giuseppe, d’Amico, Ennio, Cmentowski, Verena, Carmignani, Sara, Maffini, Stefano, Merino, Felipe, Wohlgemuth, Sabine, Vetter, Ingrid R, Raunser, Stefan, Musacchio, Andrea
Publicado 2022

Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore–microtubule attachments

por Maia, Ana R.R., Garcia, Zaira, Kabeche, Lilian, Barisic, Marin, Maffini, Stefano, Macedo-Ribeiro, Sandra, Cheeseman, Iain M., Compton, Duane A., Kaverina, Irina, Maiato, Helder
Publicado 2012

ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores

por Isokane, Mayumi, Walter, Thomas, Mahen, Robert, Nijmeijer, Bianca, Hériché, Jean-Karim, Miura, Kota, Maffini, Stefano, Ivanov, Miroslav Penchev, Kitajima, Tomoya S., Peters, Jan-Michael, Ellenberg, Jan
Publicado 2016

Centriolar distal appendages activate the centrosome‐PIDDosome‐p53 signalling axis via ANKRD26

por Burigotto, Matteo, Mattivi, Alessia, Migliorati, Daniele, Magnani, Giovanni, Valentini, Chiara, Roccuzzo, Michela, Offterdinger, Martin, Pizzato, Massimo, Schmidt, Alexander, Villunger, Andreas, Maffini, Stefano, Fava, Luca L
Publicado 2020

Electroporated recombinant proteins as tools for in vivo functional complementation, imaging and chemical biology

por Alex, Amal, Piano, Valentina, Polley, Soumitra, Stuiver, Marchel, Voss, Stephanie, Ciossani, Giuseppe, Overlack, Katharina, Voss, Beate, Wohlgemuth, Sabine, Petrovic, Arsen, Wu, Yaowen, Selenko, Philipp, Musacchio, Andrea, Maffini, Stefano
Publicado 2019

Structure of the RZZ complex and molecular basis of its interaction with Spindly

por Mosalaganti, Shyamal, Keller, Jenny, Altenfeld, Anika, Winzker, Michael, Rombaut, Pascaline, Saur, Michael, Petrovic, Arsen, Wehenkel, Annemarie, Wohlgemuth, Sabine, Müller, Franziska, Maffini, Stefano, Bange, Tanja, Herzog, Franz, Waldmann, Herbert, Raunser, Stefan, Musacchio, Andrea
Publicado 2017

Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin

por d’Amico, Ennio A., Ud Din Ahmad, Misbha, Cmentowski, Verena, Girbig, Mathias, Müller, Franziska, Wohlgemuth, Sabine, Brockmeyer, Andreas, Maffini, Stefano, Janning, Petra, Vetter, Ingrid R., Carter, Andrew P., Perrakis, Anastassis, Musacchio, Andrea
Publicado 2022

Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80

por Pesenti, Marion E., Prumbaum, Daniel, Auckland, Philip, Smith, Charlotte M., Faesen, Alex C., Petrovic, Arsen, Erent, Muriel, Maffini, Stefano, Pentakota, Satyakrishna, Weir, John R., Lin, Yu-Chih, Raunser, Stefan, McAinsh, Andrew D., Musacchio, Andrea
Publicado 2018

The pseudo GTPase CENP-M drives human kinetochore assembly

por Basilico, Federica, Maffini, Stefano, Weir, John R, Prumbaum, Daniel, Rojas, Ana M, Zimniak, Tomasz, De Antoni, Anna, Jeganathan, Sadasivam, Voss, Beate, van Gerwen, Suzan, Krenn, Veronica, Massimiliano, Lucia, Valencia, Alfonso, Vetter, Ingrid R, Herzog, Franz, Raunser, Stefan, Pasqualato, Sebastiano, Musacchio, Andrea
Publicado 2014