A Myristoyl Amide Derivative of Doxycycline Potently Targets Cancer Stem Cells (CSCs) and Prevents Spontaneous Metastasis, Without Retaining Antibiotic Activity

por Ózsvári, Béla, Magalhães, Luma G., Latimer, Joe, Kangasmetsa, Jussi, Sotgia, Federica, Lisanti, Michael P.
Publicado 2020

Discovery of a Series of Acridinones as Mechanism-Based Tubulin Assembly Inhibitors with Anticancer Activity

por Magalhaes, Luma G., Marques, Fernando B., da Fonseca, Marina B., Rogério, Kamilla R., Graebin, Cedric S., Andricopulo, Adriano D.
Publicado 2016

Structure-Based and Molecular Modeling Studies for the Discovery of Cyclic Imides as Reversible Cruzain Inhibitors With Potent Anti-Trypanosoma cruzi Activity

por Ferreira, Rafael A. A., Pauli, Ivani, Sampaio, Thiago S., de Souza, Mariana L., Ferreira, Leonardo L. G., Magalhães, Luma G., Rezende, Celso de O., Ferreira, Rafaela S., Krogh, Renata, Dias, Luiz C., Andricopulo, Adriano D.
Publicado 2019

Inhibition of Breast Cancer Cell Migration by Cyclotides Isolated from Pombalia calceolaria

por Pinto, Meri Emili F., Najas, Jhenny Z. G., Magalhães, Luma G., Bobey, Antonio F., Mendonça, Jacqueline N., Lopes, Norberto P., Leme, Flávia M., Teixeira, Simone P., Trovó, Marcelo, Andricopulo, Adriano D., Koehbach, Johannes, Gruber, Christian W., Cilli, Eduardo Maffud, Bolzani, Vanderlan S.
Publicado 2018

Multiparameter Optimization of Trypanocidal Cruzain Inhibitors With In Vivo Activity and Favorable Pharmacokinetics

por Pauli, Ivani, Rezende Jr., Celso de O., Slafer, Brian W., Dessoy, Marco A., de Souza, Mariana L., Ferreira, Leonardo L. G., Adjanohun, Abraham L. M., Ferreira, Rafaela S., Magalhães, Luma G., Krogh, Renata, Michelan-Duarte, Simone, Del Pintor, Ricardo Vaz, da Silva, Fernando B. R., Cruz, Fabio C., Dias, Luiz C., Andricopulo, Adriano D.
Publicado 2022