Microscale Thermophoresis as a Tool to Study Protein Interactions and Their Implication in Human Diseases

por Magnez, Romain, Bailly, Christian, Thuru, Xavier
Publicado 2022

A Potential Off-Target Effect of the Wnt/β-Catenin Inhibitor KYA1797K: PD-L1 Binding and Checkpoint Inhibition

por Thuru, Xavier, Magnez, Romain, Vergoten, Gérard, Bailly, Christian
Publicado 2023

PD-1/PD-L1 binding studies using microscale thermophoresis

por Magnez, Romain, Thiroux, Bryan, Taront, Solenne, Segaoula, Zacharie, Quesnel, Bruno, Thuru, Xavier
Publicado 2017

Drug Repurposing to Enhance Antitumor Response to PD-1/PD-L1 Immune Checkpoint Inhibitors

por Thuru, Xavier, Magnez, Romain, El-Bouazzati, Hassiba, Vergoten, Gérard, Quesnel, Bruno, Bailly, Christian
Publicado 2022

MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis

por Liberelle, Maxime, Magnez, Romain, Thuru, Xavier, Bencheikh, Yamina, Ravez, Severine, Quenon, Camille, Drucbert, Anne-Sophie, Foulon, Catherine, Melnyk, Patricia, Seuningen, Isabelle Van, Lebègue, Nicolas
Publicado 2019

Publisher Correction: MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis

por Liberelle, Maxime, Magnez, Romain, Thuru, Xavier, Bencheikh, Yamina, Ravez, Severine, Quenon, Camille, Drucbert, Anne-Sophie, Foulon, Catherine, Melnyk, Patricia, Van Seuningen, Isabelle, Lebègue, Nicolas
Publicado 2020

Tau Stabilizes Chromatin Compaction

por Rico, Thomas, Gilles, Melissa, Chauderlier, Alban, Comptdaer, Thomas, Magnez, Romain, Chwastyniak, Maggy, Drobecq, Herve, Pinet, Florence, Thuru, Xavier, Buée, Luc, Galas, Marie-Christine, Lefebvre, Bruno
Publicado 2021

Antioxidant Properties and Aldehyde Reactivity of PD-L1 Targeted Aryl-Pyrazolone Anticancer Agents

por Leleu-Chavain, Natascha, Regnault, Romain, Ahouari, Hania, Le Biannic, Raphaël, Kouach, Mostafa, Klupsch, Frédérique, Magnez, Romain, Vezin, Hervé, Thuru, Xavier, Bailly, Christian, Goossens, Jean-François, Millet, Régis
Publicado 2022

Novel PD-L1-Targeted Phenyl-Pyrazolone Derivatives with Antioxidant Properties

por Regnault, Romain, Klupsch, Frédérique, El-Bouazzati, Hassiba, Magnez, Romain, Le Biannic, Raphaël, Leleu-Chavain, Natascha, Ahouari, Hania, Vezin, Hervé, Millet, Régis, Goossens, Jean-François, Thuru, Xavier, Bailly, Christian
Publicado 2023

The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis

por Stoup, Nicolas, Liberelle, Maxime, Schulz, Céline, Cavdarli, Sumeyye, Vasseur, Romain, Magnez, Romain, Lahdaoui, Fatima, Skrypek, Nicolas, Peretti, Fabien, Frénois, Frédéric, Thuru, Xavier, Melnyk, Patricia, Renault, Nicolas, Jonckheere, Nicolas, Lebègue, Nicolas, Van Seuningen, Isabelle
Publicado 2021

Toward the Discovery of a Novel Class of YAP–TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP–TEAD Protein–Protein Interface

por Gibault, Floriane, Coevoet, Mathilde, Sturbaut, Manon, Farce, Amaury, Renault, Nicolas, Allemand, Frédéric, Guichou, Jean-François, Drucbert, Anne-Sophie, Foulon, Catherine, Magnez, Romain, Thuru, Xavier, Corvaisier, Matthieu, Huet, Guillemette, Chavatte, Philippe, Melnyk, Patricia, Bailly, Fabrice, Cotelle, Philippe
Publicado 2018

Functional Analyses of Two Novel LRRK2 Pathogenic Variants in Familial Parkinson′s Disease

por Coku, Ilda, Mutez, Eugénie, Eddarkaoui, Sabiha, Carrier, Sébastien, Marchand, Antoine, Deldycke, Claire, Goveas, Liesel, Baille, Guillaume, Tir, Mélissa, Magnez, Romain, Thuru, Xavier, Vermeersch, Gaëlle, Vandenberghe, Wim, Buée, Luc, Defebvre, Luc, Sablonnière, Bernard, Chartier‐Harlin, Marie‐Christine, Taymans, Jean‐Marc, Huin, Vincent
Publicado 2022

A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively

por Marchand, Antoine, Sarchione, Alessia, Athanasopoulos, Panagiotis S., Roy, Hélène Bauderlique-Le, Goveas, Liesel, Magnez, Romain, Drouyer, Matthieu, Emanuele, Marco, Ho, Franz Y., Liberelle, Maxime, Melnyk, Patricia, Lebègue, Nicolas, Thuru, Xavier, Nichols, R. Jeremy, Greggio, Elisa, Kortholt, Arjan, Galli, Thierry, Chartier-Harlin, Marie-Christine, Taymans, Jean-Marc
Publicado 2022

Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells

por Trouvilliez, Sarah, Cicero, Julien, Lévêque, Romain, Aubert, Léo, Corbet, Cyril, Van Outryve, Alexandre, Streule, Karolin, Angrand, Pierre-Olivier, Völkel, Pamela, Magnez, Romain, Brysbaert, Guillaume, Mysiorek, Caroline, Gosselet, Fabien, Bourette, Roland, Adriaenssens, Eric, Thuru, Xavier, Lagadec, Chann, de Ruyck, Jérôme, Orian-Rousseau, Véronique, Le Bourhis, Xuefen, Toillon, Robert-Alain
Publicado 2022