Rictor/mTORC2 Is Essential for Maintaining a Balance Between β-Cell Proliferation and Cell Size

por Gu, Yanyun, Lindner, Jill, Kumar, Anil, Yuan, Weiping, Magnuson, Mark A.
Publicado 2011

Ghrelin Expression in the Mouse Pancreas Defines a Unique Multipotent Progenitor Population

por Arnes, Luis, Hill, Jonathon T., Gross, Stefanie, Magnuson, Mark A., Sussel, Lori
Publicado 2012

Response to Comment on: Kumar et al. Fat Cell–Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism. Diabetes 2010;59:1...

por Kumar, Anil, Keller, Susanna R., Kim, Jason K., Magnuson, Mark A., Harris, Thurl E.
Publicado 2011

Excitotoxicity and Overnutrition Additively Impair Metabolic Function and Identity of Pancreatic β-Cells

por Osipovich, Anna B., Stancill, Jennifer S., Cartailler, Jean-Philippe, Dudek, Karrie D., Magnuson, Mark A.
Publicado 2020

Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs

por Dudek, Karrie D, Osipovich, Anna B, Cartailler, Jean-Philippe, Gu, Guoquing, Magnuson, Mark A
Publicado 2021

Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development

por Trinh, Linh T., Osipovich, Anna B., Sampson, Leesa, Wong, Jonathan, Wright, Chris V.E., Magnuson, Mark A.
Publicado 2022

Substrate-induced Nuclear Export and Peripheral Compartmentalization of Hepatic Glucokinase Correlates with Glycogen Deposition

por Jetton, Thomas L., Shiota, Masa, Knobel, Susan M., Piston, David W., Cherrington, Alan D., Magnuson, Mark A.
Publicado 2001

MafA and MafB Regulate Genes Critical to β-Cells in a Unique Temporal Manner

por Artner, Isabella, Hang, Yan, Mazur, Magdalena, Yamamoto, Tsunehiko, Guo, Min, Lindner, Jill, Magnuson, Mark A., Stein, Roland
Publicado 2010

ZFP92, a KRAB domain zinc finger protein enriched in pancreatic islets, binds to B1/Alu SINE transposable elements and regulates retroelements and genes

por Osipovich, Anna B., Dudek, Karrie D., Trinh, Linh T., Kim, Lily H., Shrestha, Shristi, Cartailler, Jean-Philippe, Magnuson, Mark A.
Publicado 2023

CAMSAP2 localizes to the Golgi in islet β-cells and facilitates Golgi-ER trafficking

por Ho, Kung-Hsien, Jayathilake, Anissa, Mahircan, Yagan, Nour, Aisha, Osipovich, Anna B., Magnuson, Mark A., Gu, Guoqiang, Kaverina, Irina
Publicado 2023

The MODY-associated TALK-1 L114P mutation causes islet α-cell overactivity and β-cell inactivity resulting in transient neonatal diabetes and glucose dyshomeostasis in adults

por Nakhe, Arya Y., Dadi, Prasanna K., Kim, Jinsun, Shrestha, Shristi, Cartailler, Jean-Philippe, Sampson, Leesa, Magnuson, Mark A., Jacobson, David A.
Publicado 2023

Deletion of Ascl1 in pancreatic β-cells improves insulin secretion, promotes parasympathetic innervation, and attenuates dedifferentiation during metabolic stress

por Osipovich, Anna B., Zhou, Frank Y., Chong, Judy J., Trinh, Linh T., Cottam, Mathew A., Shrestha, Shristi, Cartailler, Jean-Philippe, Magnuson, Mark A.
Publicado 2023

Fat Cell–Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism

por Kumar, Anil, Lawrence, John C., Jung, Dae Young, Ko, Hwi Jin, Keller, Susanna R., Kim, Jason K., Magnuson, Mark A., Harris, Thurl E.
Publicado 2010

Quantification of factors influencing fluorescent protein expression using RMCE to generate an allelic series in the ROSA26 locus in mice

por Chen, Sara X., Osipovich, Anna B., Ustione, Alessandro, Potter, Leah A., Hipkens, Susan, Gangula, Rama, Yuan, Weiping, Piston, David W., Magnuson, Mark A.
Publicado 2011

Activation of FoxM1 Revitalizes the Replicative Potential of Aged β-Cells in Male Mice and Enhances Insulin Secretion

por Golson, Maria L., Dunn, Jennifer C., Maulis, Matthew F., Dadi, Prasanna K., Osipovich, Anna B., Magnuson, Mark A., Jacobson, David A., Gannon, Maureen
Publicado 2015

Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones

por Iwafuchi, Makiko, Cuesta, Isabel, Donahue, Greg, Takenaka, Naomi, Osipovich, Anna B., Magnuson, Mark A., Roder, Heinrich, Seeholzer, Steven H., Santisteban, Pilar, Zaret, Kenneth S.
Publicado 2020

Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3

por Osipovich, Anna B., Long, Qiaoming, Manduchi, Elisabetta, Gangula, Rama, Hipkens, Susan B., Schneider, Judsen, Okubo, Tadashi, Stoeckert, Christian J., Takada, Shinji, Magnuson, Mark A.
Publicado 2014

Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells

por Bechard, Matthew E., Bankaitis, Eric D., Hipkens, Susan B., Ustione, Alessandro, Piston, David W., Yang, Yu-Ping, Magnuson, Mark A., Wright, Christopher V.E.
Publicado 2016

Deletion of Jazf1 gene causes early growth retardation and insulin resistance in mice

por Lee, Hui-Young, Jang, Hye Rim, Li, Hui, Samuel, Varman T., Dudek, Karrie D., Osipovich, Anna B., Magnuson, Mark A., Sklar, Jeffrey, Shulman, Gerald I.
Publicado 2022

Chronic β-Cell Depolarization Impairs β-Cell Identity by Disrupting a Network of Ca(2+)-Regulated Genes

por Stancill, Jennifer S., Cartailler, Jean-Philippe, Clayton, Hannah W., O’Connor, James T., Dickerson, Matthew T., Dadi, Prasanna K., Osipovich, Anna B., Jacobson, David A., Magnuson, Mark A.
Publicado 2017