Generation of CHOPe003-A ESC line to study an ACTG2 variant affecting smooth muscle development and function

por Hashmi, Sohaib K., Schneider, Sabine, Gagne, Alyssa L., Maguire, Jean Ann, Anderson, Sierra, Gadue, Paul, Heuckeroth, Robert O., French, Deborah L.
Publicado 2023

Tropomyosin 1 genetically constrains in vitro hematopoiesis

por Thom, Christopher Stephen, Jobaliya, Chintan D, Lorenz, Kimberly, Maguire, Jean Ann, Gagne, Alyssa, Gadue, Paul, French, Deborah L, Voight, Benjamin Franklin
Publicado 2020

Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL

por Gagne, Alyssa L., Maguire, Jean Ann, Gandre-Babbe, Shilpa, Chou, Stella T., Tasian, Sarah K., Loh, Mignon L., Weiss, Mitchell J., Gadue, Paul, French, Deborah L.
Publicado 2018

Generation of a human Tropomyosin 1 knockout iPSC line

por Wilken, Madison B, Maguire, Jean Ann, Dungan, Lea V, Gagne, Alyssa, Osorio-Quintero, Catherine, Waxman, Elisa A, Chou, Stella T, Gadue, Paul, French, Deborah L, Thom, Christopher S
Publicado 2023

Generation of a human Tropomyosin 1 knockout iPSC line

por Wilken, Madison B., Maguire, Jean Ann, Dungan, Lea V., Gagne, Alyssa, Osorio-Quintero, Catherine, Waxman, Elisa A, Chou, Stella T., Gadue, Paul, French, Deborah L., Thom, Christopher S.
Publicado 2023

Study of inherited thrombocytopenia resulting from mutations in ETV6 or RUNX1 using a human pluripotent stem cell model

por Borst, Sara, Nations, Catriana C., Klein, Joshua G., Pavani, Giulia, Maguire, Jean Ann, Camire, Rodney M., Drazer, Michael W., Godley, Lucy A., French, Deborah L., Poncz, Mortimer, Gadue, Paul
Publicado 2021

GATA6 Plays an Important Role in the Induction of Human Definitive Endoderm, Development of the Pancreas, and Functionality of Pancreatic β Cells

por Tiyaboonchai, Amita, Cardenas-Diaz, Fabian L., Ying, Lei, Maguire, Jean Ann, Sim, Xiuli, Jobaliya, Chintan, Gagne, Alyssa L., Kishore, Siddharth, Stanescu, Diana E., Hughes, Nkecha, De Leon, Diva D., French, Deborah L., Gadue, Paul
Publicado 2017

Tropomyosin 1 deficiency facilitates cell state transitions to enhance hemogenic endothelial cell specification during hematopoiesis

por Wilken, Madison B, Fonar, Gennadiy, Nations, Catriana, Pavani, Giulia, Tsao, Victor, Garifallou, James, Tober, Joanna, Bennett, Laura, Maguire, Jean Ann, Gagne, Alyssa, Okoli, Nkemdilim, Gadue, Paul, Chou, Stella T, Speck, Nancy A, French, Deborah L, Thom, Christopher S
Publicado 2023

Mapping PTBP2 binding in human brain identifies SYNGAP1 as a target for therapeutic splice switching

por Dawicki-McKenna, Jennine M., Felix, Alex J., Waxman, Elisa A., Cheng, Congsheng, Amado, Defne A., Ranum, Paul T., Bogush, Alexey, Dungan, Lea V., Maguire, Jean Ann, Gagne, Alyssa L., Heller, Elizabeth A., French, Deborah L., Davidson, Beverly L., Prosser, Benjamin L.
Publicado 2023

High density SNP array and reanalysis of genome sequencing uncovers CNVs associated with neurodevelopmental disorders in KOLF2.1J iPSCs

por Gracia-Diaz, Carolina, Perdomo, Jonathan E., Khan, Munir E., Disanza, Brianna, Cajka, Gregory G., Lei, Sunyimeng, Gagne, Alyssa, Maguire, Jean Ann, Roule, Thomas, Shalem, Ophir, Bhoj, Elizabeth J., Ahrens-Nicklas, Rebecca C., French, Deborah, Goldberg, Ethan M., Wang, Kai, Glessner, Joseph, Akizu, Naiara
Publicado 2023