Mitochondria as Crucial Players in Demyelinated Axons: Lessons from Neuropathology and Experimental Demyelination

por Campbell, Graham R., Mahad, Don J.
Publicado 2011

No excess of mitochondrial DNA deletions within muscle in progressive multiple sclerosis

por Campbell, Graham R, Reeve, Amy K, Ziabreva, Iryna, Reynolds, Richard, Turnbull, Doug M, Mahad, Don J
Publicado 2013

Mitochondrial fission augments capsaicin-induced axonal degeneration

por Chiang, Hao, Ohno, Nobuhiko, Hsieh, Yu-Lin, Mahad, Don J., Kikuchi, Shin, Komuro, Hitoshi, Hsieh, Sung-Tsang, Trapp, Bruce D.
Publicado 2014

Loss of protohaem IX farnesyltransferase in mature dentate granule cells impairs short‐term facilitation at mossy fibre to CA3 pyramidal cell synapses

por Booker, Sam A., Campbell, Graham R., Mysiak, Karolina S., Brophy, Peter J., Kind, Peter C., Mahad, Don J., Wyllie, David J. A.
Publicado 2017

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

por Campbell, Graham R, Ziabreva, Iryna, Reeve, Amy K, Krishnan, Kim J, Reynolds, Richard, Howell, Owen, Lassmann, Hans, Turnbull, Doug M, Mahad, Don J
Publicado 2011

Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis

por Mehta, Arpan R., Gregory, Jenna M., Dando, Owen, Carter, Roderick N., Burr, Karen, Nanda, Jyoti, Story, David, McDade, Karina, Smith, Colin, Morton, Nicholas M., Mahad, Don J., Hardingham, Giles E., Chandran, Siddharthan, Selvaraj, Bhuvaneish T.
Publicado 2021

Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis

por Licht‐Mayer, Simon, Campbell, Graham R., Mehta, Arpan R., McGill, Katie, Symonds, Alex, Al‐Azki, Sarah, Pryce, Gareth, Zandee, Stephanie, Zhao, Chao, Kipp, Markus, Smith, Kenneth J., Baker, David, Altmann, Daniel, Anderton, Stephen M., Kap, Yolanda S., Laman, Jon D., 't Hart, Bert A., Rodriguez, Moses, Franklin, Robin J. M., Chandran, Siddharthan, Lassmann, Hans, Trapp, Bruce D., Mahad, Don J.
Publicado 2022

Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis

por Licht-Mayer, Simon, Campbell, Graham R., Canizares, Marco, Mehta, Arpan R., Gane, Angus B., McGill, Katie, Ghosh, Aniket, Fullerton, Alexander, Menezes, Niels, Dean, Jasmine, Dunham, Jordon, Al-Azki, Sarah, Pryce, Gareth, Zandee, Stephanie, Zhao, Chao, Kipp, Markus, Smith, Kenneth J., Baker, David, Altmann, Daniel, Anderton, Stephen M., Kap, Yolanda S., Laman, Jon D., Hart, Bert A.‘t, Rodriguez, Moses, Watzlawick, Ralf, Schwab, Jan M., Carter, Roderick, Morton, Nicholas, Zagnoni, Michele, Franklin, Robin J. M., Mitchell, Rory, Fleetwood-Walker, Sue, Lyons, David A., Chandran, Siddharthan, Lassmann, Hans, Trapp, Bruce D., Mahad, Don J.
Publicado 2020

Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons

por Cronin, Shane J. F., Yu, Weonjin, Hale, Ashley, Licht-Mayer, Simon, Crabtree, Mark J, Korecka, Joanna A., Tretiakov, Evgenii O., Sealey-Cardona, Marco, Somlyay, Mate, Onji, Masahiro, An, Meilin, Fox, Jesse D., Turnes, Bruna Lenfers, Gomez-Diaz, Carlos, da Luz Scheffer, Débora, Cikes, Domagoj, Nagy, Vanja, Weidinger, Adelheid, Wolf, Alexandra, Reither, Harald, Chabloz, Antoine, Kavirayani, Anoop, Rao, Shuan, Andrews, Nick, Latremoliere, Alban, Costigan, Michael, Douglas, Gillian, Freitas, Fernando Cini, Pifl, Christian, Walz, Roger, Konrat, Robert, Mahad, Don J., Koslov, Andrey V., Latini, Alexandra, Isacson, Ole, Harkany, Tibor, Hallett, Penelope J., Bagby, Stefan, Woolf, Clifford J., Channon, Keith M., Je, Hyunsoo Shawn, Penninger, Josef M.
Publicado 2023