Emerging Role and Targeting of Carcinoembryonic Antigen-related Cell Adhesion Molecule 6 (CEACAM6) in Human Malignancies

por Johnson, Benny, Mahadevan, Daruka
Publicado 2015

In Silico analyses of host immunity and stroma provide prognostic factors in early stage pancreatic ductal adenocarcinoma (PDAC)

por Williams, Madison H., Mahadevan, Daruka
Publicado 2020

Clinical trials targeting neurofibromatoses-associated tumors: a systematic review

por Roman Souza, Gabriel, Abdalla, Ahmed, Mahadevan, Daruka
Publicado 2022

Reciprocal feedback inhibition of the androgen receptor and PI3K as a novel therapy for castrate-sensitive and -resistant prostate cancer

por Qi, Wenqing, Morales, Carla, Cooke, Laurence S., Johnson, Benny, Somer, Bradley, Mahadevan, Daruka
Publicado 2015

Expression Levels of RAD51 Inversely Correlate with Survival of Glioblastoma Patients

por Morrison, Christopher, Weterings, Eric, Mahadevan, Daruka, Sanan, Abhay, Weinand, Martin, Stea, Baldassarre
Publicado 2021

Using cfDNA and ctDNA as Oncologic Markers: A Path to Clinical Validation

por Dao, Jonathan, Conway, Patrick J., Subramani, Baskaran, Meyyappan, Devi, Russell, Sammy, Mahadevan, Daruka
Publicado 2023

The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells

por Welsh, James W, Mahadevan, Daruka, Ellsworth, Ron, Cooke, Laurence, Bearss, David, Stea, Baldassarre
Publicado 2009

A Comparative Analysis of Tumors and Plasma Circulating Tumor DNA in 145 Advanced Cancer Patients Annotated by 3 Core Cellular Processes

por Larson, Kristian, Kannaiyan, Radhamani, Pandey, Ritu, Chen, Yuliang, Babiker, Hani M., Mahadevan, Daruka
Publicado 2020

Co-targeting aurora kinase with PD-L1 and PI3K abrogates immune checkpoint mediated proliferation in peripheral T-cell lymphoma: a novel therapeutic strategy

por Islam, Shariful, Vick, Eric, Huber, Bryan, Morales, Carla, Spier, Catherine, Cooke, Laurence, Weterings, Eric, Mahadevan, Daruka
Publicado 2017

TP53 Mutations as a Driver of Metastasis Signaling in Advanced Cancer Patients

por Pandey, Ritu, Johnson, Nathan, Cooke, Laurence, Johnson, Benny, Chen, Yuliang, Pandey, Manjari, Chandler, Jason, Mahadevan, Daruka
Publicado 2021

Drug-induced aneuploidy and polyploidy is a mechanism of disease relapse in MYC/BCL2-addicted diffuse large B-cell lymphoma

por Islam, Shariful, Paek, Andrew L., Hammer, Michael, Rangarajan, Savithri, Ruijtenbeek, Robert, Cooke, Laurence, Weterings, Eric, Mahadevan, Daruka
Publicado 2018

Rare Tumor-Normal Matched Whole Exome Sequencing Identifies Novel Genomic Pathogenic Germline and Somatic Aberrations

por Sprissler, Ryan, Perkins, Bryce, Johnstone, Laurel, Babiker, Hani M., Chalasani, Pavani, Lau, Branden, Hammer, Michael, Mahadevan, Daruka
Publicado 2020

MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer

por Qi, Wenqing, Cooke, Larry S, Stejskal, Amy, Riley, Christopher, Croce, Kimiko Della, Saldanha, Jose W, Bearss, David, Mahadevan, Daruka
Publicado 2009

PD-1-Associated Gene Expression Signature of Neoadjuvant Trastuzumab-Treated Tumors Correlates with Patient Survival in HER2-Positive Breast Cancer

por Hendricks, William P. D., Briones, Natalia, Halperin, Rebecca F., Facista, Salvatore, Heaton, Paul R., Mahadevan, Daruka, Kim, Suwon
Publicado 2019

DNA methylation biomarkers discovered in silico detect cancer in liquid biopsies from non-small cell lung cancer patients

por Vrba, Lukas, Oshiro, Marc M., Kim, Samuel S., Garland, Linda L., Placencia, Crystal, Mahadevan, Daruka, Nelson, Mark A., Futscher, Bernard W.
Publicado 2019

Novel receptor tyrosine kinase targeted combination therapies for imatinib-resistant gastrointestinal stromal tumors (GIST)

por Mahadevan, Daruka, Theiss, Noah, Morales, Carla, Stejskal, Amy E., Cooke, Laurence S., Zhu, Min, Kurtzman, Drew, Swart, Rachel, Ong, Evan, Qi, Wenqing
Publicado 2014

Gene Expression and Serum Cytokine Profiling of Low Stage CLL Identify WNT/PCP, Flt-3L/Flt-3 and CXCL9/CXCR3 as Regulators of Cell Proliferation, Survival and Migration

por Mahadevan, Daruka, Choi, James, Cooke, Laurence, Simons, Bram, Riley, Christopher, Klinkhammer, Thomas, Sud, Rohit, Maddipoti, Sirisha, Hehn, Sean, Garewal, Harinder, Spier, Catherine
Publicado 2009

Alisertib Added to Rituximab and Vincristine Is Synthetic Lethal and Potentially Curative in Mice with Aggressive DLBCL Co-Overexpressing MYC and BCL2

por Mahadevan, Daruka, Morales, Carla, Cooke, Laurence S., Manziello, Ann, Mount, David W., Persky, Daniel O., Fisher, Richard I., Miller, Thomas P., Qi, Wenqing
Publicado 2014

Carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6) in Pancreatic Ductal Adenocarcinoma (PDA): An integrative analysis of a novel therapeutic target

por Pandey, Ritu, Zhou, Muhan, Islam, Shariful, Chen, Baowei, Barker, Natalie K, Langlais, Paul, Srivastava, Anup, Luo, Moulun, Cooke, Laurence S., Weterings, Eric, Mahadevan, Daruka
Publicado 2019

Safety and efficacy of the tumor-selective adenovirus enadenotucirev, in combination with nivolumab, in patients with advanced/metastatic epithelial cancer: a phase I clinical tria...

por Fakih, Marwan, Harb, Wael, Mahadevan, Daruka, Babiker, Hani, Berlin, Jordan, Lillie, Tom, Krige, David, Carter, Jo, Cox, Chris, Patel, Minesh, Parfitt, Lola, Powell, Mark, Rosen, Lee
Publicado 2023