Flavonoids Targeting Cancer Stem Cells for Augmenting Cancer Therapeutics

por Meerson, Ari, Khatib, Soliman, Mahajna, Jamal
Publicado 2021

2-Hydroxyestradiol Overcomes Mesenchymal Stem Cells-Mediated Platinum Chemoresistance in Ovarian Cancer Cells in an ERK-Independent Fashion

por Khamaisi, Hazem, Mahmoud, Hatem, Mahajna, Jamal
Publicado 2022

Natural products as potential cancer therapy enhancers: A preclinical update

por Agbarya, Abed, Ruimi, Nili, Epelbaum, Ron, Ben-Arye, Eran, Mahajna, Jamal
Publicado 2014

Platinum (IV)-fatty acid conjugates overcome inherently and acquired Cisplatin resistant cancer cell lines: an in-vitro study

por Ratzon, Einav, Najajreh, Yousef, Salem, Rami, Khamaisie, Hazem, Ruthardt, Martin, Mahajna, Jamal
Publicado 2016

Mesenchymal soluble factors confer imatinib drug resistance in chronic myelogenous leukemia cells

por Regev, Ofer, Kidan, Noa, Nicola, Meshel, Khamisie, Hazem, Ruthardt, Martin, Mahajna, Jamal
Publicado 2020

Secreted Soluble Factors from Tumor-Activated Mesenchymal Stromal Cells Confer Platinum Chemoresistance to Ovarian Cancer Cells

por Koren Carmi, Yifat, Khamaisi, Hazem, Adawi, Rina, Noyman, Eden, Gopas, Jacob, Mahajna, Jamal
Publicado 2023

Flavonoids Restore Platinum Drug Sensitivity to Ovarian Carcinoma Cells in a Phospho-ERK1/2-Dependent Fashion

por Koren Carmi, Yifat, Mahmoud, Hatem, Khamaisi, Hazem, Adawi, Rina, Gopas, Jacob, Mahajna, Jamal
Publicado 2020

Overcoming Bcr-Abl T315I mutation by combination of GNF-2 and ATP competitors in an Abl-independent mechanism

por Khateb, Mamduh, Ruimi, Nili, Khamisie, Hazem, Najajreh, Yousef, Mian, Afsar, Metodieva, Anna, Ruthardt, Martin, Mahajna, Jamal
Publicado 2012

Ectopic Expression of Snail and Twist in Ph+ Leukemia Cells Upregulates CD44 Expression and Alters Their Differentiation Potential

por Kidan, Noa, Khamaisie, Hazem, Ruimi, Nili, Roitman, Shay, Eshel, Elizabeth, Dally, Najib, Ruthardt, Martin, Mahajna, Jamal
Publicado 2017

Natural Products Counteracting Cardiotoxicity during Cancer Chemotherapy: The Special Case of Doxorubicin, a Comprehensive Review

por Koss-Mikołajczyk, Izabela, Todorovic, Vanja, Sobajic, Sladjana, Mahajna, Jamal, Gerić, Marko, Tur, Josep A., Bartoszek, Agnieszka
Publicado 2021

Compounds originating from the edible mushroom Auricularia auricula-judae inhibit tropomyosin receptor kinase B activity

por Shahar, Orr, Pereman, Idan, Khamisie, Hazem, Ezov, Nirit, Danay, Ofer, Khattib, Ali, schweitzer, Ron, Khatib, Soliman, Mahajna, Jamal
Publicado 2023

TRAF3 suppression encourages B cell recruitment and prolongs survival of microbiome-intact mice with ovarian cancer

por Zorea, Jonathan, Motro, Yair, Mazor, Roei D., Carmi, Yifat Koren, Shulman, Ziv, Mahajna, Jamal, Moran-Gilad, Jacob, Elkabets, Moshe
Publicado 2023

Allosteric inhibition enhances the efficacy of ABL kinase inhibitors to target unmutated BCR-ABL and BCR-ABL-T315I

por Mian, Afsar Ali, Metodieva, Anna, Badura, Susanne, Khateb, Mamduh, Ruimi, Nili, Najajreh, Yousef, Ottmann, Oliver Gerhard, Mahajna, Jamal, Ruthardt, Martin
Publicado 2012

Plant-Derived Epi-Nutraceuticals as Potential Broad-Spectrum Anti-Viral Agents

por Gabbianelli, Rosita, Shahar, Ehud, de Simone, Gaia, Rucci, Chiara, Bordoni, Laura, Feliziani, Giulia, Zhao, Fanrui, Ferrati, Marta, Maggi, Filippo, Spinozzi, Eleonora, Mahajna, Jamal
Publicado 2023

Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1(T315I) and...

por Mian, Afsar Ali, Haberbosch, Isabella, Khamaisie, Hazem, Agbarya, Abed, Pietsch, Larissa, Eshel, Elizabeh, Najib, Dally, Chiriches, Claudia, Ottmann, Oliver Gerhard, Hantschel, Oliver, Biondi, Ricardo M., Ruthardt, Martin, Mahajna, Jamal
Publicado 2021