The drug interaction potential of daprodustat when coadministered with pioglitazone, rosuvastatin, or trimethoprim in healthy subjects

por Caltabiano, Stephen, Mahar, Kelly M., Lister, Karyn, Tenero, David, Ravindranath, Ramiya, Cizman, Borut, Cobitz, Alexander R.
Publicado 2018

A randomized, 29-day, dose-ranging, efficacy and safety study of daprodustat, administered three times weekly in patients with anemia on hemodialysis

por Bailey, Christine K., Caltabiano, Stephen, Cobitz, Alexander R., Huang, Chun, Mahar, Kelly M., Patel, Vickas V.
Publicado 2019

A Single‐Dose, Open‐Label, Randomized, Two‐Way Crossover Study in Healthy Japanese Participants to Evaluate the Bioequivalence and the Food Effect on the Pharmacokinetics of Daprod...

por Yamada, Masanori, Osamura, Minori, Ogura, Hirofumi, Onoue, Tomohiro, Wakamatsu, Akira, Numachi, Yotaro, Caltabiano, Stephen, Mahar, Kelly M.
Publicado 2020

Pharmacokinetics of Daprodustat and Metabolites in Individuals with Normal and Impaired Hepatic Function

por Mahar, Kelly M., Shaddinger, Bonnie C., Ramanjineyulu, Bandi, Andrews, Susan, Caltabiano, Stephen, Lindsay, Alistair C., Cobitz, Alexander R.
Publicado 2022

Effects of Urotensin II Receptor Antagonist, GSK1440115, in Asthma

por Portnoy, Alison, Kumar, Sanjay, Behm, David J., Mahar, Kelly M., Noble, Robert B., Throup, John P., Russ, Steven F.
Publicado 2013

Effect of renal function and dialysis modality on daprodustat and predominant metabolite exposure

por Caltabiano, Stephen, Cizman, Borut, Burns, Olivia, Mahar, Kelly M, Johnson, Brendan M, Ramanjineyulu, Bandi, Serbest, Gulyeter, Cobitz, Alexander R
Publicado 2019

Clinical Pharmacokinetics of Daprodustat: Results of an Absorption, Distribution, and Excretion Study With Intravenous Microtracer and Concomitant Oral Doses for Bioavailability De...

por Mahar, Kelly M., Caltabiano, Stephen, Andrews, Susan, Ramanjineyulu, Bandi, Chen, Liangfu, Young, Graeme, Pereira, Adrian, Lindsay, Alistair C., van den Berg, Frans, Cobitz, Alexander R.
Publicado 2021