What Role Does COA6 Play in Cytochrome C Oxidase Biogenesis: A Metallochaperone or Thiol Oxidoreductase, or Both?

por Maghool, Shadi, Ryan, Michael T., Maher, Megan J.
Publicado 2020

The structure of the complex between the arsenite oxidase from Pseudorhizobium banfieldiae sp. strain NT-26 and its native electron acceptor cytochrome c (552)

por Poddar, Nilakhi, Santini, Joanne M., Maher, Megan J.
Publicado 2023

Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-­fluoroorotate: catalytic activity is reflected by the crystal form

por Lee, Mihwa, Maher, Megan J., Guss, J. Mitchell
Publicado 2007

The Initiation of GTP Hydrolysis by the G-Domain of FeoB: Insights from a Transition-State Complex Structure

por Ash, Miriam-Rose, Maher, Megan J., Guss, J. Mitchell, Jormakka, Mika
Publicado 2011

Exploring the correlation between the sequence composition of the nucleotide binding G5 loop of the FeoB GTPase domain (NFeoB) and intrinsic rate of GDP release

por Guilfoyle, Amy P., Deshpande, Chandrika N., Schenk, Gerhard, Maher, Megan J., Jormakka, Mika
Publicado 2014

Human glutaredoxin-1 can transfer copper to isolated metal binding domains of the P(1B)-type ATPase, ATP7B

por Maghool, Shadi, Fontaine, Sharon La, Roberts, Blaine R., Kwan, Ann H., Maher, Megan J.
Publicado 2020

Structural and functional characterization of the mitochondrial complex IV assembly factor Coa6

por Maghool, Shadi, Cooray, N Dinesha G, Stroud, David A, Aragão, David, Ryan, Michael T, Maher, Megan J
Publicado 2019

Crystal structure of A(3)B(3) complex of V-ATPase from Thermus thermophilus

por Maher, Megan J, Akimoto, Satoru, Iwata, Momi, Nagata, Koji, Hori, Yoshiko, Yoshida, Masasuke, Yokoyama, Shigeyuki, Iwata, So, Yokoyama, Ken
Publicado 2009

Mitochondrial COA7 is a heme-binding protein with disulfide reductase activity, which acts in the early stages of complex IV assembly

por Formosa, Luke E., Maghool, Shadi, Sharpe, Alice J., Reljic, Boris, Muellner-Wong, Linden, Stroud, David A., Ryan, Michael T., Maher, Megan J.
Publicado 2022

Thioredoxin A Active-Site Mutants Form Mixed Disulfide Dimers That Resemble Enzyme–Substrate Reaction Intermediates

por Kouwen, Thijs R.H.M., Andréll, Juni, Schrijver, Rianne, Dubois, Jean-Yves F., Maher, Megan J., Iwata, So, Carpenter, Elisabeth P., van Dijl, Jan Maarten
Publicado 2008

Structural basis of interprotein electron transfer in bacterial sulfite oxidation

por McGrath, Aaron P, Laming, Elise L, Casas Garcia, G Patricia, Kvansakul, Marc, Guss, J Mitchell, Trewhella, Jill, Calmes, Benoit, Bernhardt, Paul V, Hanson, Graeme R, Kappler, Ulrike, Maher, Megan J
Publicado 2015

Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae

por Begg, Stephanie L., Eijkelkamp, Bart A., Luo, Zhenyao, Couñago, Rafael M., Morey, Jacqueline R., Maher, Megan J., Ong, Cheryl-lynn Y., McEwan, Alastair G., Kobe, Bostjan, O’Mara, Megan L., Paton, James C., McDevitt, Christopher A.
Publicado 2015

The structural basis of bacterial manganese import

por Neville, Stephanie L., Sjöhamn, Jennie, Watts, Jacinta A., MacDermott-Opeskin, Hugo, Fairweather, Stephen J., Ganio, Katherine, Carey Hulyer, Alex, McGrath, Aaron P., Hayes, Andrew J., Malcolm, Tess R., Davies, Mark R., Nomura, Norimichi, Iwata, So, O’Mara, Megan L., Maher, Megan J., McDevitt, Christopher A.
Publicado 2021

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

por Monk, Ian R., Shaikh, Nausad, Begg, Stephanie L., Gajdiss, Mike, Sharkey, Liam K. R., Lee, Jean Y. H., Pidot, Sacha J., Seemann, Torsten, Kuiper, Michael, Winnen, Brit, Hvorup, Rikki, Collins, Brett M., Bierbaum, Gabriele, Udagedara, Saumya R., Morey, Jacqueline R., Pulyani, Neha, Howden, Benjamin P., Maher, Megan J., McDevitt, Christopher A., King, Glenn F., Stinear, Timothy P.
Publicado 2019

Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

por Brazel, Erin B., Tan, Aimee, Neville, Stephanie L., Iverson, Amy R., Udagedara, Saumya R., Cunningham, Bliss A., Sikanyika, Mwilye, De Oliveira, David M.P., Keller, Bernhard, Bohlmann, Lisa, El-Deeb, Ibrahim M., Ganio, Katherine, Eijkelkamp, Bart A., McEwan, Alastair G., von Itzstein, Mark, Maher, Megan J., Walker, Mark J., Rosch, Jason W., McDevitt, Christopher A.
Publicado 2022