Cloud Computing Based Immunopeptidomics Utilizing Community Curated Variant Libraries Simplifies and Improves Neo-Antigen Discovery in Metastatic Melanoma

por Prakash, Amol, Mahoney, Keira E., Orsburn, Benjamin C.
Publicado 2021

MHC Phosphopeptides: Promising Targets for Immunotherapy of Cancer and Other Chronic Diseases

por Mahoney, Keira E., Shabanowitz, Jeffrey, Hunt, Donald F.
Publicado 2021

False-Positive Glycopeptide Identification via In-FAIMS Fragmentation

por Rangel-Angarita, Valentina, Mahoney, Keira E., Kwon, Catherine, Sarker, Raibat, Lucas, Taryn M., Malaker, Stacy A.
Publicado 2023

Bump-and-hole engineering of human polypeptide N-acetylgalactosamine transferases to dissect their protein substrates and glycosylation sites in cells

por Calle, Beatriz, Gonzalez-Rodriguez, Edgar, Mahoney, Keira E., Cioce, Anna, Bineva-Todd, Ganka, Tastan, Omur Y., Roustan, Chloe, Flynn, Helen, Malaker, Stacy A., Schumann, Benjamin
Publicado 2023

A previously uncharacterized O-glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond

por Medley, Brendon J., Leclaire, Leif, Thompson, Nicole, Mahoney, Keira E., Pluvinage, Benjamin, Parson, Matthew A.H., Burke, John E., Malaker, Stacy, Wakarchuk, Warren, Boraston, Alisdair B.
Publicado 2022

Murine xenograft bioreactors for human immunopeptidome discovery

por Heather, James M., Myers, Paisley T., Shi, Feng, Aziz-Zanjani, Mohammad Ovais, Mahoney, Keira E., Perez, Matthew, Morin, Benjamin, Brittsan, Christine, Shabanowitz, Jeffrey, Hunt, Donald F., Cobbold, Mark
Publicado 2019

Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE

por Chongsaritsinsuk, Joann, Steigmeyer, Alexandra D., Mahoney, Keira E., Rosenfeld, Mia A., Lucas, Taryn M., Ince, Deniz, Kearns, Fiona L., Battison, Alexandria S., Hollenhorst, Marie A., Shon, D. Judy, Tiemeyer, Katherine H., Attah, Victor, Kwon, Catherine, Bertozzi, Carolyn R., Ferracane, Michael J., Amaro, Rommie E., Malaker, Stacy A.
Publicado 2023

Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE

por Chongsaritsinsuk, Joann, Steigmeyer, Alexandra D., Mahoney, Keira E., Rosenfeld, Mia A., Lucas, Taryn M., Smith, Courtney M., Li, Alice, Ince, Deniz, Kearns, Fiona L., Battison, Alexandria S., Hollenhorst, Marie A., Judy Shon, D., Tiemeyer, Katherine H., Attah, Victor, Kwon, Catherine, Bertozzi, Carolyn R., Ferracane, Michael J., Lemmon, Mark A., Amaro, Rommie E., Malaker, Stacy A.
Publicado 2023

MHC-restricted phosphopeptide antigens: preclinical validation and first-in-humans clinical trial in participants with high-risk melanoma

por Engelhard, Victor H, Obeng, Rebecca C, Cummings, Kara L, Petroni, Gina R, Ambakhutwala, Angela L, Chianese-Bullock, Kimberly A, Smith, Kelly T, Lulu, Amanda, Varhegyi, Nikole, Smolkin, Mark E, Myers, Paisley, Mahoney, Keira E, Shabanowitz, Jeffrey, Buettner, Nico, Hall, Emily H, Haden, Kathleen, Cobbold, Mark, Hunt, Donald F, Weiss, Geoffrey, Gaughan, Elizabeth, Slingluff, Jr, Craig L
Publicado 2020

O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Likely Contribute to the Mutational Trajectory in Variants of Concern

por Gonzalez-Rodriguez, Edgar, Zol-Hanlon, Mia, Bineva-Todd, Ganka, Marchesi, Andrea, Skehel, Mark, Mahoney, Keira E., Roustan, Chloë, Borg, Annabel, Di Vagno, Lucia, Kjær, Svend, Wrobel, Antoni G., Benton, Donald J., Nawrath, Philipp, Flitsch, Sabine L., Joshi, Dhira, González-Ramírez, Andrés Manuel, Wilkinson, Katalin A., Wilkinson, Robert J., Wall, Emma C., Hurtado-Guerrero, Ramón, Malaker, Stacy A., Schumann, Benjamin
Publicado 2023

Reinspection of a Clinical Proteomics Tumor Analysis Consortium (CPTAC) Dataset with Cloud Computing Reveals Abundant Post-Translational Modifications and Protein Sequence Variants

por Prakash, Amol, Taylor, Lorne, Varkey, Manu, Hoxie, Nate, Mohammed, Yassene, Goo, Young Ah, Peterman, Scott, Moghekar, Abhay, Yuan, Yuting, Glaros, Trevor, Steele, Joel R., Faridi, Pouya, Parihari, Shashwati, Srivastava, Sanjeeva, Otto, Joseph J., Nyalwidhe, Julius O., Semmes, O. John, Moran, Michael F., Madugundu, Anil, Mun, Dong Gi, Pandey, Akhilesh, Mahoney, Keira E., Shabanowitz, Jeffrey, Saxena, Satya, Orsburn, Benjamin C.
Publicado 2021

Cell-specific bioorthogonal tagging of glycoproteins

por Cioce, Anna, Calle, Beatriz, Rizou, Tatiana, Lowery, Sarah C., Bridgeman, Victoria L., Mahoney, Keira E., Marchesi, Andrea, Bineva-Todd, Ganka, Flynn, Helen, Li, Zhen, Tastan, Omur Y., Roustan, Chloe, Soro-Barrio, Pablo, Rafiee, Mahmoud-Reza, Garza-Garcia, Acely, Antonopoulos, Aristotelis, Wood, Thomas M., Keenan, Tessa, Both, Peter, Huang, Kun, Parmeggian, Fabio, Snijders, Ambrosius P., Skehel, Mark, Kjær, Svend, Fascione, Martin A., Bertozzi, Carolyn R., Haslam, Stuart M., Flitsch, Sabine L., Malaker, Stacy A., Malanchi, Ilaria, Schumann, Benjamin
Publicado 2022