Structural and Functional Insights into GID/CTLH E3 Ligase Complexes

por Maitland, Matthew E. R., Lajoie, Gilles A., Shaw, Gary S., Schild-Poulter, Caroline
Publicado 2022

Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex

por Salemi, Louisa M., Maitland, Matthew E. R., Yefet, Eyal R., Schild-Poulter, Caroline
Publicado 2017

Cell signalling pathway regulation by RanBPM: molecular insights and disease implications

por Salemi, Louisa M., Maitland, Matthew E. R., McTavish, Christina J., Schild-Poulter, Caroline
Publicado 2017

Proteomic analysis of ubiquitination substrates reveals a CTLH E3 ligase complex‐dependent regulation of glycolysis

por Maitland, Matthew E. R., Kuljanin, Miljan, Wang, Xu, Lajoie, Gilles A., Schild‐Poulter, Caroline
Publicado 2021

Noncanonical functions of Ku may underlie essentiality in human cells

por Kelly, Rachel D., Parmar, Gursimran, Bayat, Laila, Maitland, Matthew E. R., Lajoie, Gilles A., Edgell, David R., Schild-Poulter, Caroline
Publicado 2023

Regulation of c-Raf Stability through the CTLH Complex

por McTavish, Christina J., Bérubé-Janzen, Wesley, Wang, Xu, Maitland, Matthew E. R., Salemi, Louisa M., Hess, David A., Schild-Poulter, Caroline
Publicado 2019

The mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation

por Maitland, Matthew E. R., Onea, Gabriel, Chiasson, Christopher A., Wang, Xu, Ma, Jun, Moor, Sarah E., Barber, Kathryn R., Lajoie, Gilles A., Shaw, Gary S., Schild-Poulter, Caroline
Publicado 2019

Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer’s disease phenotype in mice

por Gould, Nathaniel L., Scherer, Gila R., Carvalho, Silvia, Shurrush, Khriesto, Kayyal, Haneen, Edry, Efrat, Elkobi, Alina, David, Orit, Foqara, Maria, Thakar, Darshit, Pavesi, Tommaso, Sharma, Vijendra, Walker, Matthew, Maitland, Matthew, Dym, Orly, Albeck, Shira, Peleg, Yoav, Germain, Nicolas, Babaev, Ilana, Sharir, Haleli, Lalzar, Maya, Shklyar, Boris, Hazut, Neta, Khamaisy, Mohammad, Lévesque, Maxime, Lajoie, Gilles, Avoli, Massimo, Amitai, Gabriel, Lefker, Bruce, Subramanyam, Chakrapani, Shilton, Brian, Barr, Haim, Rosenblum, Kobi
Publicado 2023

Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo

por Lackie, Rachel E., de Miranda, Aline S., Lim, Mei Peng, Novikov, Vladislav, Madrer, Nimrod, Karunatilleke, Nadun C., Rutledge, Benjamin S., Tullo, Stephanie, Brickenden, Anne, Maitland, Matthew E. R., Greenberg, David, Gallino, Daniel, Luo, Wen, Attaran, Anoosha, Shlaifer, Irina, Del Cid Pellitero, Esther, Schild-Poulter, Caroline, Durcan, Thomas M., Fon, Edward A., Duennwald, Martin, Beraldo, Flavio H., Chakravarty, M. Mallar, Bussey, Timothy J., Saksida, Lisa M., Soreq, Hermona, Choy, Wing-Yiu, Prado, Vania F., Prado, Marco A. M.
Publicado 2022