A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein

por Landeck, Natalie, Hall, Hélène, Ardah, Mustafa T., Majbour, Nour K., El-Agnaf, Omar M. A., Halliday, Glenda, Kirik, Deniz
Publicado 2016

Cerebrospinal Fluid α-Synuclein Species in Cognitive and Movements Disorders

por Constantinides, Vasilios C., Majbour, Nour K., Paraskevas, George P., Abdi, Ilham, Safieh-Garabedian, Bared, Stefanis, Leonidas, El-Agnaf, Omar M., Kapaki, Elisabeth
Publicado 2021

Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease

por Majbour, Nour K., Chiasserini, Davide, Vaikath, Nishant N., Eusebi, Paolo, Tokuda, Takahiko, van de Berg, Wilma, Parnetti, Lucilla, Calabresi, Paolo, El-Agnaf , Omar M. A.
Publicado 2017

Preanalytical Stability of CSF Total and Oligomeric Alpha-Synuclein

por Abdi, Ilham Y., Majbour, Nour K., Willemse, Eline A. J., van de Berg, Wilma D. J., Mollenhauer, Brit, Teunissen, Charlotte E., El-Agnaf, Omar M.
Publicado 2021

Levels of cerebrospinal fluid α-synuclein oligomers are increased in Parkinson’s disease with dementia and dementia with Lewy bodies compared to Alzheimer’s disease

por Hansson, Oskar, Hall, Sara, Öhrfelt, Annika, Zetterberg, Henrik, Blennow, Kaj, Minthon, Lennart, Nägga, Katarina, Londos, Elisabet, Varghese, Shiji, Majbour, Nour K, Al-Hayani, Abdulmonem, El-Agnaf, Omar MA
Publicado 2014

Differential role of CSF alpha-synuclein species, tau, and Aβ42 in Parkinson's Disease

por Parnetti, Lucilla, Farotti, Lucia, Eusebi, Paolo, Chiasserini, Davide, De Carlo, Claudia, Giannandrea, David, Salvadori, Nicola, Lisetti, Viviana, Tambasco, Nicola, Rossi, Aroldo, Majbour, Nour K., El-Agnaf, Omar, Calabresi, Paolo
Publicado 2014

CSF or serum neurofilament light added to α‐Synuclein panel discriminates Parkinson's from controls

por Oosterveld, Linda P., Verberk, Inge M.W., Majbour, Nour K., El‐Agnaf, Omar M., Weinstein, Henry C., Berendse, Henk W., Teunissen, Charlotte E., van de Berg, Wilma D.J.
Publicado 2019

Investigating the presence of doubly phosphorylated α‐synuclein at tyrosine 125 and serine 129 in idiopathic Lewy body diseases

por Fayyad, Muneera, Erskine, Daniel, Majbour, Nour K., Vaikath, Nishant N., Ghanem, Simona S., Sudhakaran, Indulekha P., Abdesselem, Houari, Lamprokostopoulou, Agaristi, Vekrellis, Kostas, Morris, Christopher M., Attems, Johannes, El‐Agnaf, Omar M. A.
Publicado 2020

Elevated levels of cerebrospinal fluid α-synuclein oligomers in healthy asymptomatic LRRK2 mutation carriers

por Aasly, Jan O., Johansen, Krisztina K., Brønstad, Gunnar, Warø, Bjørg J., Majbour, Nour K., Varghese, Shiji, Alzahmi, Fatimah, Paleologou, Katerina E., Amer, Dena A. M., Al-Hayani, Abdulmonem, El-Agnaf, Omar M. A.
Publicado 2014

α‐Synuclein species as potential cerebrospinal fluid biomarkers for dementia with lewy bodies

por van Steenoven, Inger, Majbour, Nour K., Vaikath, Nishant N., Berendse, Henk W., van der Flier, Wiesje M., van de Berg, Wilma D.J., Teunissen, Charlotte E., Lemstra, Afina W., El‐Agnaf, Omar M.A.
Publicado 2018

CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers

por Majbour, Nour K., Aasly, Jan O., Hustad, Eldbjørg, Thomas, Mercy A., Vaikath, Nishant N., Elkum, Naser, van de Berg, Wilma D. J., Tokuda, Takahiko, Mollenhauer, Brit, Berendse, Henk W., El-Agnaf, Omar M. A.
Publicado 2020

Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity

por Gupta, Vijay, Salim, Safa, Hmila, Issam, Vaikath, Nishant N., Sudhakaran, Indulekha P., Ghanem, Simona S., Majbour, Nour K., Abdulla, Sara A., Emara, Mohamed M., Abdesselem, Houari B., Lukacsovich, Tamas, Erskine, Daniel, El-Agnaf, Omar M. A.
Publicado 2020

Novel engineered nanobodies specific for N‐terminal region of alpha‐synuclein recognize Lewy‐body pathology and inhibit in‐vitro seeded aggregation and toxicity

por Hmila, Issam, Vaikath, Nishant N., Majbour, Nour K., Erskine, Daniel, Sudhakaran, Indulekha P., Gupta, Vijay, Ghanem, Simona S., Islam, Zeyaul, Emara, Mohamed M., Abdesselem, Houari B., Kolatkar, Prasanna R., Achappa, Devaya K., Vinardell, Tatiana, El‐Agnaf, Omar M. A.
Publicado 2022

CSF Biomarkers Reflecting Protein Pathology and Axonal Degeneration Are Associated with Memory, Attentional, and Executive Functioning in Early-Stage Parkinson′s Disease

por Oosterveld, Linda P., Kuiper, Tessa I., Majbour, Nour K., Verberk, Inge M. W., van Dijk, Karin D., Twisk, Jos W. R., El-Agnaf, Omar M., Teunissen, Charlotte E., Weinstein, Henry C., Klein, Martin, Berendse, Henk W., van de Berg, Wilma D. J.
Publicado 2020

Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease

por Majbour, Nour K., Vaikath, Nishant N., van Dijk, Karin D., Ardah, Mustafa T., Varghese, Shiji, Vesterager, Louise B., Montezinho, Liliana P., Poole, Stephen, Safieh-Garabedian, Bared, Tokuda, Takahiko, Teunissen, Charlotte E., Berendse, Henk W., van de Berg, Wilma D. J., El-Agnaf, Omar M. A.
Publicado 2016

Uncovering a neurological protein signature for severe COVID-19

por El-Agnaf, Omar, Bensmail, Ilham, Al-Nesf, Maryam A.Y., Flynn, James, Taylor, Mark, Majbour, Nour K., Abdi, Ilham Y., Vaikath, Nishant N., Farooq, Abdulaziz, Vemulapalli, Praveen B., Schmidt, Frank, Ouararhni, Khalid, Al-Siddiqi, Heba H., Arredouani, Abdelilah, Wijten, Patrick, Al-Maadheed, Mohammed, Mohamed-Ali, Vidya, Decock, Julie, Abdesselem, Houari B.
Publicado 2023

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

por Duffy, Megan F., Collier, Timothy J., Patterson, Joseph R., Kemp, Christopher J., Luk, Kelvin C., Tansey, Malú G., Paumier, Katrina L., Kanaan, Nicholas M., Fischer, Luke D., Polinski, Nicole K., Barth, Olivia L., Howe, Jacob W., Vaikath, Nishant N., Majbour, Nour K., El-Agnaf, Omar M. A., Sortwell, Caryl E.
Publicado 2018

Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

por Duffy, Megan F., Collier, Timothy J., Patterson, Joseph R., Kemp, Christopher J., Luk, Kelvin C., Tansey, Malú G., Paumier, Katrina L., Kanaan, Nicholas M., Fischer, D. Luke, Polinski, Nicole K., Barth, Olivia L., Howe, Jacob W., Vaikath, Nishant N., Majbour, Nour K., El-Agnaf, Omar M. A., Sortwell, Caryl E.
Publicado 2018

Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects

por Tomlinson, Julianna J., Shutinoski, Bojan, Dong, Li, Meng, Fanyi, Elleithy, Dina, Lengacher, Nathalie A., Nguyen, Angela P., Cron, Greg O., Jiang, Qiubo, Roberson, Erik D., Nussbaum, Robert L., Majbour, Nour K., El-Agnaf, Omar M., Bennett, Steffany A., Lagace, Diane C., Woulfe, John M., Sad, Subash, Brown, Earl G., Schlossmacher, Michael G.
Publicado 2017

α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity

por Ghanem, Simona S., Majbour, Nour K., Vaikath, Nishant N., Ardah, Mustafa T., Erskine, Daniel, Jensen, Nanna Møller, Fayyad, Muneera, Sudhakaran, Indulekha P., Vasili, Eftychia, Melachroinou, Katerina, Abdi, Ilham Y., Poggiolini, Ilaria, Santos, Patricia, Dorn, Anton, Carloni, Paolo, Vekrellis, Kostas, Attems, Johannes, McKeith, Ian, Outeiro, Tiago F., Jensen, Poul Henning, El-Agnaf, Omar M. A.
Publicado 2022