The cancer stem cell model: B cell acute lymphoblastic leukaemia breaks the mould

por McClellan, James Scott, Majeti, Ravindra
Publicado 2013

Preleukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia

por Corces, M. Ryan, Chang, Howard Y., Majeti, Ravindra
Publicado 2017

Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations wi...

por Jonas, Brian A., Johnson, Carl, Gratzinger, Dita, Majeti, Ravindra
Publicado 2016

Centrosome-Kinase Fusions Promote Oncogenic Signaling and Disrupt Centrosome Function in Myeloproliferative Neoplasms

por Lee, Joanna Y., Hong, Wan-Jen, Majeti, Ravindra, Stearns, Tim
Publicado 2014

An LSC epigenetic signature is largely mutation independent and implicates the HOXA cluster in AML pathogenesis

por Jung, Namyoung, Dai, Bo, Gentles, Andrew J., Majeti, Ravindra, Feinberg, Andrew P.
Publicado 2015

Mebendazole for Differentiation Therapy of Acute Myeloid Leukemia Identified by a Lineage Maturation Index

por Li, Yulin, Thomas, Daniel, Deutzmann, Anja, Majeti, Ravindra, Felsher, Dean W., Dill, David L.
Publicado 2019

Clonal architecture predicts clinical outcomes and drug sensitivity in acute myeloid leukemia

por Benard, Brooks A., Leak, Logan B., Azizi, Armon, Thomas, Daniel, Gentles, Andrew J., Majeti, Ravindra
Publicado 2021

Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6

por Bak, Rasmus O, Dever, Daniel P, Reinisch, Andreas, Cruz Hernandez, David, Majeti, Ravindra, Porteus, Matthew H
Publicado 2017

Correction: Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6

por Bak, Rasmus O, Dever, Daniel P, Reinisch, Andreas, Cruz Hernandez, David, Majeti, Ravindra, Porteus, Matthew H
Publicado 2018

Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA

por Xu, Jin, Nuno, Kevin, Litzenburger, Ulrike M, Qi, Yanyan, Corces, M Ryan, Majeti, Ravindra, Chang, Howard Y
Publicado 2019

Convergent Epigenetic Evolution Drives Relapse in Acute Myeloid Leukemia

por Nuno, Kevin A., Azizi, Armon, Köhnke, Thomas, Lareau, Caleb A., Ediwirickrema, Asiri, Ryan Corces, M., Satpathy, Ansuman T., Majeti, Ravindra
Publicado 2023

A Humanized Ossicle-niche Xenotransplantation Model Enables Improved Human Leukemic Engraftment

por Reinisch, Andreas, Thomas, Daniel, Corces, M. Ryan, Zhang, Xiaohua, Gratzinger, Dita, Hong, Wan-Jen, Schallmoser, Katharina, Strunk, Dirk, Majeti, Ravindra
Publicado 2016

Autophagy mediates proteolysis of NPM1 and HEXIM1 and sensitivity to BET inhibition in AML cells

por Huang, Min, Garcia, Jacqueline S., Thomas, Daniel, Zhu, Li, Nguyen, Le Xuan Truong, Chan, Steven M., Majeti, Ravindra, Medeiros, Bruno C., Mitchell, Beverly S.
Publicado 2016

The TRACE-Seq method tracks recombination alleles and identifies clonal reconstitution dynamics of gene targeted human hematopoietic stem cells

por Sharma, Rajiv, Dever, Daniel P., Lee, Ciaran M., Azizi, Armon, Pan, Yidan, Camarena, Joab, Köhnke, Thomas, Bao, Gang, Porteus, Matthew H., Majeti, Ravindra
Publicado 2021

Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies

por Chao, Mark P., Takimoto, Chris H., Feng, Dong Dong, McKenna, Kelly, Gip, Phung, Liu, Jie, Volkmer, Jens-Peter, Weissman, Irving L., Majeti, Ravindra
Publicado 2020

TP53-Mutated Myelodysplastic Syndrome and Acute Myeloid Leukemia: Biology, Current Therapy, and Future Directions

por Daver, Naval G., Maiti, Abhishek, Kadia, Tapan M., Vyas, Paresh, Majeti, Ravindra, Wei, Andrew H., Garcia-Manero, Guillermo, Craddock, Charles, Sallman, David A., Kantarjian, Hagop M.
Publicado 2022

RUNX1 loss renders hematopoietic and leukemic cells dependent on IL-3 and sensitive to JAK inhibition

por Fan, Amy C., Nakauchi, Yusuke, Bai, Lawrence, Azizi, Armon, Nuno, Kevin A., Zhao, Feifei, Köhnke, Thomas, Karigane, Daiki, Cruz-Hernandez, David, Reinisch, Andreas, Khatri, Purvesh, Majeti, Ravindra
Publicado 2023

Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential

por Liu, Jie, Wang, Lijuan, Zhao, Feifei, Tseng, Serena, Narayanan, Cyndhavi, Shura, Lei, Willingham, Stephen, Howard, Maureen, Prohaska, Susan, Volkmer, Jens, Chao, Mark, Weissman, Irving L., Majeti, Ravindra
Publicado 2015

Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data

por Sinha, Subarna, Thomas, Daniel, Chan, Steven, Gao, Yang, Brunen, Diede, Torabi, Damoun, Reinisch, Andreas, Hernandez, David, Chan, Andy, Rankin, Erinn B., Bernards, Rene, Majeti, Ravindra, Dill, David L.
Publicado 2017

CytofIn enables integrated analysis of public mass cytometry datasets using generalized anchors

por Lo, Yu-Chen, Keyes, Timothy J., Jager, Astraea, Sarno, Jolanda, Domizi, Pablo, Majeti, Ravindra, Sakamoto, Kathleen M., Lacayo, Norman, Mullighan, Charles G., Waters, Jeffrey, Sahaf, Bita, Bendall, Sean C., Davis, Kara L.
Publicado 2022