Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors

por Donahue, Elizabeth H, Dawson, Lisa F, Valiente, Esmeralda, Firth-Clark, Stuart, Major, Meriel R, Littler, Eddy, Perrior, Trevor R, Wren, Brendan W
Publicado 2014

Synthesis, Anti-tubulin and Antiproliferative SAR of Steroidomimetic Dihydroisoquinolinones

por Leese, Mathew P, Jourdan, Fabrice L, Major, Meriel R, Dohle, Wolfgang, Thomas, Mark P, Hamel, Ernest, Ferrandis, Eric, Mahon, Mary F, Newman, Simon P, Purohit, Atul, Potter, Barry V L
Publicado 2014

The Discovery of Potent, Selective, and Reversible Inhibitors of the House Dust Mite Peptidase Allergen Der p 1: An Innovative Approach to the Treatment of Allergic Asthma

por Newton, Gary K., Perrior, Trevor R., Jenkins, Kerry, Major, Meriel R., Key, Rebekah E., Stewart, Mark R., Firth-Clark, Stuart, Lloyd, Steven M., Zhang, Jihui, Francis-Newton, Nicola J., Richardson, Jonathan P., Chen, Jie, Lai, Pei, Garrod, David R., Robinson, Clive
Publicado 2014

Targeting an Initiator Allergen Provides Durable and Expansive Protection against House Dust Mite Allergy

por Zhang, Jihui, Chen, Jie, Richardson, Jonathan P., Francis-Newton, Nicola-Jane, Lai, Pei F., Jenkins, Kerry, Major, Meriel R., Key, Rebekah E., Stewart, Mark E., Firth-Clark, Stuart, Lloyd, Steven M., Newton, Gary K., Perrior, Trevor R., Garrod, David R., Robinson, Clive
Publicado 2022