Approximating Isotope Distributions of Biomolecule Fragments

por Goldfarb, Dennis, Lafferty, Michael J., Herring, Laura E., Wang, Wei, Major, Michael B.
Publicado 2018

Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability

por Stratford, Jeran K., Yan, Feng, Hill, Rebecca A., Major, Michael B., Graves, Lee M., Der, Channing J., Yeh, Jen Jen
Publicado 2017

The mucolipidosis IV Ca(2+) channel TRPML1 (MCOLN1) is regulated by the TOR kinase

por Onyenwoke, Rob U., Sexton, Jonathan Z., Yan, Feng, Díaz, María Cristina Huertas, Forsberg, Lawrence J., Major, Michael B., Brenman, Jay E.
Publicado 2015

The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells

por Gao, Yanzhe, Kardos, Jordan, Yang, Yang, Tamir, Tigist Y., Mutter-Rottmayer, Elizabeth, Weissman, Bernard, Major, Michael B., Kim, William Y., Vaziri, Cyrus
Publicado 2018

Wilms Tumor Gene on X Chromosome (WTX) Inhibits Degradation of NRF2 Protein through Competitive Binding to KEAP1 Protein

por Camp, Nathan D., James, Richard G., Dawson, David W., Yan, Feng, Davison, James M., Houck, Scott A., Tang, Xiaobo, Zheng, Ning, Major, Michael B., Moon, Randall T.
Publicado 2012

FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells

por Conrad, Willliam, Major, Michael B, Cleary, Michele A, Ferrer, Marc, Roberts, Brian, Marine, Shane, Chung, Namjin, Arthur, William T, Moon, Randall T, Berndt, Jason D, Chien, Andy J
Publicado 2013

Ginger Compound [6]-Shogaol and Its Cysteine-Conjugated Metabolite (M2) Activate Nrf2 in Colon Epithelial Cells in Vitro and in Vivo

por Chen, Huadong, Fu, Junsheng, Chen, Hao, Hu, Yuhui, Soroka, Dominique N., Prigge, Justin R., Schmidt, Edward E., Yan, Feng, Major, Michael B., Chen, Xiaoxin, Sang, Shengmin
Publicado 2014

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis

por Gao, Yanzhe, Mutter-Rottmayer, Elizabeth, Greenwalt, Alicia M., Goldfarb, Dennis, Yan, Feng, Yang, Yang, Martinez-Chacin, Raquel C., Pearce, Kenneth H., Tateishi, Satoshi, Major, Michael B., Vaziri, Cyrus
Publicado 2016

Protein proximity networks and functional evaluation of the casein kinase 1 gamma family reveal unique roles for CK1γ3 in WNT signaling

por Agajanian, Megan J., Potjewyd, Frances M., Bowman, Brittany M., Solomon, Smaranda, LaPak, Kyle M., Bhatt, Dhaval P., Smith, Jeffery L., Goldfarb, Dennis, Axtman, Alison D., Major, Michael B.
Publicado 2022

Ccdc94 Protects Cells from Ionizing Radiation by Inhibiting the Expression of p53

por Sorrells, Shelly, Carbonneau, Seth, Harrington, Erik, Chen, Aye T., Hast, Bridgid, Milash, Brett, Pyati, Ujwal, Major, Michael B., Zhou, Yi, Zon, Leonard I., Stewart, Rodney A., Look, A. Thomas, Jette, Cicely
Publicado 2012

WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma

por Arensman, Michael D., Kovochich, Anne N., Kulikauskas, Rima M., Lay, Anna R., Yang, Pei-Tzu, Li, Xinmin, Donahue, Timothy, Major, Michael B., Moon, Randall T., Chien, Andy J., Dawson, David W.
Publicado 2013

WIKI4, a Novel Inhibitor of Tankyrase and Wnt/ß-Catenin Signaling

por James, Richard G., Davidson, Kathryn C., Bosch, Katherine A., Biechele, Travis L., Robin, Nicholas C., Taylor, Russell J., Major, Michael B., Camp, Nathan D., Fowler, Kerry, Martins, Timothy J., Moon, Randall T.
Publicado 2012

Weight loss reduces basal-like breast cancer through kinome reprogramming

por Qin, Yuanyuan, Sundaram, Sneha, Essaid, Luma, Chen, Xin, Miller, Samantha M., Yan, Feng, Darr, David B., Galanko, Joseph A., Montgomery, Stephanie A., Major, Michael B., Johnson, Gary L., Troester, Melissa A., Makowski, Liza
Publicado 2016

STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity

por Zhu, Zhichuan, Zhou, Xin, Du, Hongwei, Cloer, Erica W., Zhang, Jiaming, Mei, Liu, Wang, Ying, Tan, Xianming, Hepperla, Austin J., Simon, Jeremy M., Cook, Jeanette Gowen, Major, Michael B., Dotti, Gianpietro, Liu, Pengda
Publicado 2022

Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding

por Skrajna, Aleksandra, Goldfarb, Dennis, Kedziora, Katarzyna M, Cousins, Emily M, Grant, Gavin D, Spangler, Cathy J, Barbour, Emily H, Yan, Xiaokang, Hathaway, Nathaniel A, Brown, Nicholas G, Cook, Jeanette G, Major, Michael B, McGinty, Robert K
Publicado 2020

Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice

por Bhatt, Dhaval P., Mills, C. Allie, Anderson, Kristin A., Henriques, Bárbara J., Lucas, Tânia G., Francisco, Sara, Liu, Juan, Ilkayeva, Olga R., Adams, Alexander E., Kulkarni, Shreyas R., Backos, Donald S., Major, Michael B., Grimsrud, Paul A., Gomes, Cláudio M., Hirschey, Matthew D.
Publicado 2022

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

por Harrison, Joseph S, Cornett, Evan M, Goldfarb, Dennis, DaRosa, Paul A, Li, Zimeng M, Yan, Feng, Dickson, Bradley M, Guo, Angela H, Cantu, Daniel V, Kaustov, Lilia, Brown, Peter J, Arrowsmith, Cheryl H, Erie, Dorothy A, Major, Michael B, Klevit, Rachel E, Krajewski, Krzysztof, Kuhlman, Brian, Strahl, Brian D, Rothbart, Scott B
Publicado 2016

Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCC

por Wamsley, Nathan T., Wilkerson, Emily M., Guan, Li, LaPak, Kyle M., Schrank, Travis P., Holmes, Brittany J., Sprung, Robert W., Gilmore, Petra Erdmann, Gerndt, Sophie P., Jackson, Ryan S., Paniello, Randal C., Pipkorn, Patrik, Puram, Sidharth V., Rich, Jason T., Townsend, Reid R., Zevallos, José P., Zolkind, Paul, Le, Quynh-Thu, Goldfarb, Dennis, Major, Michael B.
Publicado 2023

WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop

por Agajanian, Megan J., Walker, Matthew P., Axtman, Alison D., Ruela-de-Sousa, Roberta R., Serafin, D. Stephen, Rabinowitz, Alex D., Graham, David M., Ryan, Meagan B., Tamir, Tigist, Nakamichi, Yuko, Gammons, Melissa V., Bennett, James M., Couñago, Rafael M., Drewry, David H., Elkins, Jonathan M., Gileadi, Carina, Gileadi, Opher, Godoi, Paulo H., Kapadia, Nirav, Müller, Susanne, Santiago, André S., Sorrell, Fiona J., Wells, Carrow I., Fedorov, Oleg, Willson, Timothy M., Zuercher, William J., Major, Michael B.
Publicado 2019

Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract

por Zhang, Jianan, Walker, Morgan E., Sanidad, Katherine Z., Zhang, Hongna, Liang, Yanshan, Zhao, Ermin, Chacon-Vargas, Katherine, Yeliseyev, Vladimir, Parsonnet, Julie, Haggerty, Thomas D., Wang, Guangqiang, Simpson, Joshua B., Jariwala, Parth B., Beaty, Violet V., Yang, Jun, Yang, Haixia, Panigrahy, Anand, Minter, Lisa M., Kim, Daeyoung, Gibbons, John G., Liu, LinShu, Li, Zhengze, Xiao, Hang, Borlandelli, Valentina, Overkleeft, Hermen S., Cloer, Erica W., Major, Michael B., Goldfarb, Dennis, Cai, Zongwei, Redinbo, Matthew R., Zhang, Guodong
Publicado 2022