Neuroprotection Against MPP(+)-Induced Cytotoxicity Through the Activation of PI3-K/Akt/GSK3β/MEF2D Signaling Pathway by Rhynchophylline, the Major Tetracyclic Oxindole Alkaloid Is...

por Hu, Shengquan, Mak, Shinghung, Zuo, Xialin, Li, Haitao, Wang, Yuqiang, Han, Yifan
Publicado 2018

A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor

por Hu, Shengquan, Hu, Huihui, Mak, Shinghung, Cui, Guozhen, Lee, Mingyuen, Shan, Luchen, Wang, Yuqiang, Lin, Huangquan, Zhang, Zaijun, Han, Yifan
Publicado 2018

Unexpected Neuronal Protection of SU5416 against 1-Methyl-4-Phenylpyridinium Ion-Induced Toxicity via Inhibiting Neuronal Nitric Oxide Synthase

por Cui, Wei, Zhang, Zaijun, Li, Wenming, Mak, Shinghung, Hu, Shengquan, Zhang, Huan, Yuan, Shuai, Rong, Jianhui, Choi, Tony Chunglit, Lee, Simon M. Y., Han, Yifan
Publicado 2012

Interacting with α7 nAChR is a new mechanism for AChE to enhance the inflammatory response in macrophages

por Liu, Etta Y.L., Xia, Yingjie, Kong, Xiangpeng, Guo, Maggie S.S., Yu, Anna X.D., Zheng, Brody Z.Y., Mak, Shinghung, Xu, Miranda L., Tsim, Karl W.K.
Publicado 2020

Tacrine(10)-Hupyridone Prevents Post-operative Cognitive Dysfunction via the Activation of BDNF Pathway and the Inhibition of AChE in Aged Mice

por Chen, Huixin, Wu, Xiang, Gu, Xinmei, Zhou, Yiying, Ye, Luying, Zhang, Ke, Pan, Hanbo, Wang, Jialing, Wei, Hua, Zhu, Binbin, Naman, C. Benjamin, Mak, Shinghung, Carlier, Paul R., Cui, Wei, Han, Yifan
Publicado 2018

Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin

por Chang, Lan, Cui, Wei, Yang, Yong, Xu, Shujun, Zhou, Wenhua, Fu, Hongjun, Hu, Shengquan, Mak, Shinghung, Hu, Juwei, Wang, Qin, Pui-Yan Ma, Victor, Chung-lit Choi, Tony, Dik-lung Ma, Edmond, Tao, Liang, Pang, Yuanping, Rowan, Michael J., Anwyl, Roger, Han, Yifan, Wang, Qinwen
Publicado 2015