Machine learning-coupled combinatorial mutagenesis enables resource-efficient engineering of CRISPR-Cas9 genome editor activities

por Thean, Dawn G. L., Chu, Hoi Yee, Fong, John H. C., Chan, Becky K. C., Zhou, Peng, Kwok, Cynthia C. S., Chan, Yee Man, Mak, Silvia Y. L., Choi, Gigi C. G., Ho, Joshua W. K., Zheng, Zongli, Wong, Alan S. L.
Publicado 2022

High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination

por Yuen, Chaya T L, Thean, Dawn G L, Chan, Becky K C, Zhou, Peng, Kwok, Cynthia C S, Chu, Hoi Yee, Cheung, Maggie S H, Wang, Bei, Chan, Yee Man, Mak, Silvia Y L, Leung, Anskar Y, Choi, Gigi C G, Zheng, Zongli, Wong, Alan S L
Publicado 2022